|
| Status |
Public on Aug 09, 2018 |
| Title |
Diagnosis of Kawasaki Disease in children using host RNA expression [Validation_HT12V3_Dataset] |
| Organism |
Homo sapiens |
| Experiment type |
Expression profiling by array
|
| Summary |
Genome-wide analysis of transcriptional profiles in children <17 years of age with inflammatory diseases, bacterial or viral infections or with clinical features suggestive of infection.
|
| |
|
| Overall design |
Patients were recruited at or after presentation to hospital. Main inclusion criteria were presence of illness of sufficient severity to warrant blood tests for clinical reasons, in child aged <17 years. Blood was collected into PAX gene tubes (PreAnalytiX). Total RNA integrity was assessed using an Agilent 2100 Bioanalyzer (Agilent, Palo Alto, CA). Labeled cRNA was hybridized to Illumina Human HT-12 V3 Beadchips (Validation set). Numbers of arrays analysed in the validation set were as follows: Kawasaki Disease (n=1), Healthy controls (n=16), Definite Bacterial infection (n=23), Definite Viral infection (n=28), infections of uncertain bacterial or viral aetiology (n=79).
|
| |
|
| Citation(s) |
30083721 |
| |
| Submission date |
Sep 25, 2015 |
| Last update date |
Aug 16, 2018 |
| Contact name |
Victoria Wright |
| E-mail(s) |
[email protected]
|
| Organization name |
Imperial College London
|
| Department |
Paediatrics
|
| Lab |
Wright Fleming Institute
|
| Street address |
Norfolk Place
|
| City |
London |
| ZIP/Postal code |
W2 1PG |
| Country |
United Kingdom |
| |
|
| Platforms (1) |
| GPL6947 |
Illumina HumanHT-12 V3.0 expression beadchip |
|
| Samples (147)
|
|
| This SubSeries is part of SuperSeries: |
| GSE73464 |
Diagnosis of Kawasaki Disease in children using host RNA expression |
|
| Relations |
| BioProject |
PRJNA297153 |
Less...
More...