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Colonic neoplasm

MedGen UID:
3165
•Concept ID:
C0009375
•
Neoplastic Process
Synonyms: Colonic Neoplasms; Neoplasm of the colon
SNOMED CT: Neoplasm of colon (126838000); Tumor of colon (126838000)
 
HPO: HP:0100273
Monarch Initiative: MONDO:0005401

Definition

A benign or malignant neoplasm that affects the colon. Representative examples of benign neoplasms include lipoma and leiomyoma. Representative examples of malignant neoplasms include carcinoma, lymphoma, and sarcoma. Colonic adenomas always exhibit epithelial dysplasia and are considered premalignant neoplasms. [from NCI]

Term Hierarchy

CClinical test,  RResearch test,  OOMIM,  GGeneReviews,  VClinVar  
  • CROGVColonic neoplasm

Professional guidelines

PubMed

Results of a national survey on the use of stents for the treatment of colonic obstruction.
Alonso-Hernández N, Segura-Sampedro JJ, Soldevila Verdeguer CM, Ochogavía Seguí A, Olea Martinez-Mediero JM, Fernández Isart M, Gamundi Cuesta M, González-Argente XF
Cir Esp (Engl Ed) 2020 Nov;98(9):533-539. Epub 2020 Mar 24 doi: 10.1016/j.ciresp.2020.02.006. PMID: 32220416
Evolution of surgical microwave ablation for the treatment of colorectal cancer liver metastasis: review of the literature and a single centre experience.
Stättner S, Primavesi F, Yip VS, Jones RP, Öfner D, Malik HZ, Fenwick SW, Poston GJ
Surg Today 2015 Apr;45(4):407-15. Epub 2014 Mar 16 doi: 10.1007/s00595-014-0879-3. PMID: 24633931
Symptomatic colonic lipoma: differential diagnosis of large bowel tumors.
Bardají M, Roset F, Camps R, Sant F, Fernández-Layos MJ
Int J Colorectal Dis 1998;13(1):1-2. doi: 10.1007/s003840050122. PMID: 9548092

Recent clinical studies

Etiology

Optimal glycaemic control and the reduced risk of colorectal adenoma and cancer in patients with diabetes: a population-based cohort study.
Mao X, Cheung KS, Tan JT, Mak LY, Lee CH, Chiang CL, Cheng HM, Hui RW, Yuen MF, Leung WK, Seto WK
Gut 2024 Jul 11;73(8):1313-1320. doi: 10.1136/gutjnl-2023-331701. PMID: 38569845
Colon Carcinogenesis: The Interplay Between Diet and Gut Microbiota.
Loke YL, Chew MT, Ngeow YF, Lim WWD, Peh SC
Front Cell Infect Microbiol 2020;10:603086. Epub 2020 Dec 8 doi: 10.3389/fcimb.2020.603086. PMID: 33364203Free PMC Article
The risk of colonic adenomas and colonic cancer in obesity.
Laiyemo AO
Best Pract Res Clin Gastroenterol 2014 Aug;28(4):655-63. Epub 2014 Jul 10 doi: 10.1016/j.bpg.2014.07.007. PMID: 25194182Free PMC Article
Helicobacter pylori but not gastrin is associated with the development of colonic neoplasms.
Selgrad M, Bornschein J, Kandulski A, Hille C, Weigt J, Roessner A, Wex T, Malfertheiner P
Int J Cancer 2014 Sep 1;135(5):1127-31. Epub 2014 Feb 11 doi: 10.1002/ijc.28758. PMID: 24496701
Appendicitis in the elderly.
Lee JF, Leow CK, Lau WY
Aust N Z J Surg 2000 Aug;70(8):593-6. doi: 10.1046/j.1440-1622.2000.01905.x. PMID: 10945554

Diagnosis

Optimal glycaemic control and the reduced risk of colorectal adenoma and cancer in patients with diabetes: a population-based cohort study.
Mao X, Cheung KS, Tan JT, Mak LY, Lee CH, Chiang CL, Cheng HM, Hui RW, Yuen MF, Leung WK, Seto WK
Gut 2024 Jul 11;73(8):1313-1320. doi: 10.1136/gutjnl-2023-331701. PMID: 38569845
Undifferentiated colonic neoplasm with SMARCA4 germline gene mutation and loss of SMARCA4 protein expression: a case report and literature review.
Duan H, Gao W, Wang L, Cao F, Teng L
Diagn Pathol 2021 Apr 9;16(1):30. doi: 10.1186/s13000-021-01091-6. PMID: 33836796Free PMC Article
Factors contributing to time to diagnosis in symptomatic colorectal cancer: A scoping review.
Golding H, Webber CE, Groome PA
Eur J Cancer Care (Engl) 2021 May;30(3):e13397. Epub 2020 Dec 30 doi: 10.1111/ecc.13397. PMID: 33377574
Metabolic dysfunction and early-onset colorectal cancer - how macrophages build the bridge.
Scheurlen KM, Billeter AT, O'Brien SJ, Galandiuk S
Cancer Med 2020 Sep;9(18):6679-6693. Epub 2020 Jul 23 doi: 10.1002/cam4.3315. PMID: 33624450Free PMC Article
Appendicitis in the elderly.
Lee JF, Leow CK, Lau WY
Aust N Z J Surg 2000 Aug;70(8):593-6. doi: 10.1046/j.1440-1622.2000.01905.x. PMID: 10945554

Therapy

Results of a national survey on the use of stents for the treatment of colonic obstruction.
Alonso-Hernández N, Segura-Sampedro JJ, Soldevila Verdeguer CM, Ochogavía Seguí A, Olea Martinez-Mediero JM, Fernández Isart M, Gamundi Cuesta M, González-Argente XF
Cir Esp (Engl Ed) 2020 Nov;98(9):533-539. Epub 2020 Mar 24 doi: 10.1016/j.ciresp.2020.02.006. PMID: 32220416
Downregulation of lncRNA CCAT1 enhances 5-fluorouracil sensitivity in human colon cancer cells.
Yang C, Pan Y, Deng SP
BMC Mol Cell Biol 2019 Apr 23;20(1):9. doi: 10.1186/s12860-019-0188-1. PMID: 31039730Free PMC Article
Hepatitis B Virus Infection Is Independently Associated With Advanced Colorectal Adenoma.
Kim SH, Kim JW, Lee KL, Lee S, Koh SJ, Jeong JB, Kim BG
Am J Med Sci 2018 Aug;356(2):141-146. Epub 2018 May 2 doi: 10.1016/j.amjms.2018.04.016. PMID: 30219156
Rethinking Priorities: Cost of Complications After Elective Colectomy.
Zogg CK, Najjar P, Diaz AJ, Zogg DL, Tsai TC, Rose JA Jr, Scott JW, Gani F, Alshaikh H, Canner JK, Schneider EB, Goldberg JE, Haider AH
Ann Surg 2016 Aug;264(2):312-22. doi: 10.1097/SLA.0000000000001511. PMID: 26501705
Appendicitis in the elderly.
Lee JF, Leow CK, Lau WY
Aust N Z J Surg 2000 Aug;70(8):593-6. doi: 10.1046/j.1440-1622.2000.01905.x. PMID: 10945554

Prognosis

Undifferentiated colonic neoplasm with SMARCA4 germline gene mutation and loss of SMARCA4 protein expression: a case report and literature review.
Duan H, Gao W, Wang L, Cao F, Teng L
Diagn Pathol 2021 Apr 9;16(1):30. doi: 10.1186/s13000-021-01091-6. PMID: 33836796Free PMC Article
Metabolic dysfunction and early-onset colorectal cancer - how macrophages build the bridge.
Scheurlen KM, Billeter AT, O'Brien SJ, Galandiuk S
Cancer Med 2020 Sep;9(18):6679-6693. Epub 2020 Jul 23 doi: 10.1002/cam4.3315. PMID: 33624450Free PMC Article
Colorectal neoplasm and acromegaly.
Bhansali A, Dutta P, Bhat MH, Sinha SK, Kochar R, Vaiphi K
Pituitary 2006;9(3):259-61. doi: 10.1007/s11102-006-8816-0. PMID: 17072515
Colonic adenocarcinoma metastasizing as a germ cell neoplasm: a case report and review of the literature.
Petricek CM
Arch Pathol Lab Med 2001 Apr;125(4):558-61. doi: 10.5858/2001-125-0558-CAMAAG. PMID: 11260638
Single-layer continuous colorectal anastomosis.
Bailey HR, LaVoo JW, Max E, Smith KW, Hampton JM
Aust N Z J Surg 1981 Oct;51(5):473-6. doi: 10.1111/j.1445-2197.1981.tb05989.x. PMID: 7032490

Clinical prediction guides

Optimal glycaemic control and the reduced risk of colorectal adenoma and cancer in patients with diabetes: a population-based cohort study.
Mao X, Cheung KS, Tan JT, Mak LY, Lee CH, Chiang CL, Cheng HM, Hui RW, Yuen MF, Leung WK, Seto WK
Gut 2024 Jul 11;73(8):1313-1320. doi: 10.1136/gutjnl-2023-331701. PMID: 38569845
Prediction of advanced colonic neoplasm in symptomatic patients: a scoring system to prioritize colonoscopy (COLONOFIT study).
Fernández-Bañares F, Clèries R, Boadas J, Ribes J, Oliva JC, Alsius A, Sanz X, Martínez-Bauer E, Galter S, Pujals M, Pujol M, Del Pozo P, Campo R
BMC Cancer 2019 Jul 25;19(1):734. doi: 10.1186/s12885-019-5926-4. PMID: 31345180Free PMC Article
The yield of colonic biopsy in the evaluation of chronic unexplained diarrhea.
Genta RM, Sonnenberg A
Eur J Gastroenterol Hepatol 2015 Aug;27(8):963-7. doi: 10.1097/MEG.0000000000000365. PMID: 26114907
Clinical and endoscopic predictors of colorectal adenoma recurrence after colon polypectomy.
Jang ES, Kim JW, Jung YJ, Jeong JB, Kim BG, Lee KL, Kim JS, Jung HC, Song IS
Turk J Gastroenterol 2013;24(6):476-82. doi: 10.4318/tjg.2013.0610. PMID: 24623285
Appendicitis in the elderly.
Lee JF, Leow CK, Lau WY
Aust N Z J Surg 2000 Aug;70(8):593-6. doi: 10.1046/j.1440-1622.2000.01905.x. PMID: 10945554

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