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Colon medullary carcinoma

MedGen UID:
363630
•Concept ID:
C1880119
•
Neoplastic Process
Synonyms: Colon Medullary Carcinoma; colon medullary carcinoma; medullary carcinoma of the colon; medullary colon carcinoma
 
Monarch Initiative: MONDO:0000892

Definition

A rare, invasive colon adenocarcinoma characterized by the presence of sheets of malignant epithelial cells with vesicular nuclei, prominent nucleoli, and abundant eosinophilic cytoplasm. It usually has a favorable prognosis. [from NCI]

Term Hierarchy

CClinical test,  RResearch test,  OOMIM,  GGeneReviews,  VClinVar  
  • CROGVColon medullary carcinoma

Professional guidelines

PubMed

Novel Criteria for Intratumoral Budding with Prognostic Relevance for Colon Cancer and Its Histological Subtypes.
Pour Farid P, Eckstein M, Merkel S, Grützmann R, Hartmann A, Bruns V, Benz M, Schneider-Stock R, Geppert CI
Int J Mol Sci 2021 Dec 3;22(23) doi: 10.3390/ijms222313108. PMID: 34884913Free PMC Article
Clinicopathologic profile, immunophenotype, and genotype of CD274 (PD-L1)-positive colorectal carcinomas.
Inaguma S, Lasota J, Wang Z, Felisiak-Golabek A, Ikeda H, Miettinen M
Mod Pathol 2017 Feb;30(2):278-285. Epub 2016 Nov 4 doi: 10.1038/modpathol.2016.185. PMID: 27813511Free PMC Article
Tumor markers: value and limitations in the management of cancer patients.
Bates SE, Longo DL
Cancer Treat Rev 1985 Sep;12(3):163-207. doi: 10.1016/0305-7372(85)90037-4. PMID: 2416441

Recent clinical studies

Etiology

Risk factor analysis and nomogram development and verification for medullary carcinoma of the colon using SEER database.
Yang L, Yu L, Zhou Q, Liu L, Shen N, Li N
Sci Rep 2024 May 19;14(1):11426. doi: 10.1038/s41598-024-61354-2. PMID: 38763982Free PMC Article

Diagnosis

Risk factor analysis and nomogram development and verification for medullary carcinoma of the colon using SEER database.
Yang L, Yu L, Zhou Q, Liu L, Shen N, Li N
Sci Rep 2024 May 19;14(1):11426. doi: 10.1038/s41598-024-61354-2. PMID: 38763982Free PMC Article
Mismatch repair proteins immunohistochemical null phenotype in colon medullary carcinoma.
Tatsuta K, Sakata M, Iwaizumi M, Shinmura K, Akai T, Kawamura T, Torii K, Morita Y, Kikuchi H, Hiramatsu Y, Fukazawa A, Kurachi K, Takeuchi H
Clin J Gastroenterol 2021 Oct;14(5):1448-1452. Epub 2021 Jul 19 doi: 10.1007/s12328-021-01484-6. PMID: 34279804

Therapy

Risk factor analysis and nomogram development and verification for medullary carcinoma of the colon using SEER database.
Yang L, Yu L, Zhou Q, Liu L, Shen N, Li N
Sci Rep 2024 May 19;14(1):11426. doi: 10.1038/s41598-024-61354-2. PMID: 38763982Free PMC Article

Prognosis

Risk factor analysis and nomogram development and verification for medullary carcinoma of the colon using SEER database.
Yang L, Yu L, Zhou Q, Liu L, Shen N, Li N
Sci Rep 2024 May 19;14(1):11426. doi: 10.1038/s41598-024-61354-2. PMID: 38763982Free PMC Article

Clinical prediction guides

Risk factor analysis and nomogram development and verification for medullary carcinoma of the colon using SEER database.
Yang L, Yu L, Zhou Q, Liu L, Shen N, Li N
Sci Rep 2024 May 19;14(1):11426. doi: 10.1038/s41598-024-61354-2. PMID: 38763982Free PMC Article

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