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Metastatic Colon Adenocarcinoma

MedGen UID:: 1685225
•Concept ID:: C4324497
•: Neoplastic Process

Definition

An adenocarcinoma that arises from the colon and has metastasized to another anatomic site. [from NCI]

Term Hierarchy

GTR
MeSH

CClinical test, RResearch test, OOMIM, GGeneReviews, VClinVar

CROGVMetastatic Colon Adenocarcinoma

Neoplasm
- Epithelial neoplasm
  - Carcinoma
    - Adenocarcinoma
      - Adenocarcinoma of the large intestine
        Colon adenocarcinoma
        Metastatic Colon Adenocarcinoma
        Advanced Colon Adenocarcinoma
        Locally Advanced Unresectable Colon Adenocarcinoma

Professional guidelines

PubMed

Surgical management of extensive peristomal pyoderma gangrenosum associated with colon cancer.

Ishikawa K, Minamimoto T, Mizuki T, Furukawa H
J Wound Ostomy Continence Nurs 2015 Jan-Feb;42(1):102-5. doi: 10.1097/WON.0000000000000098. PMID: 25549316

See all (1)

Recent clinical studies

Etiology

Mutational analysis and clinical correlation of metastatic colorectal cancer.

Russo AL, Borger DR, Szymonifka J, Ryan DP, Wo JY, Blaszkowsky LS, Kwak EL, Allen JN, Wadlow RC, Zhu AX, Murphy JE, Faris JE, Dias-Santagata D, Haigis KM, Ellisen LW, Iafrate AJ, Hong TS
Cancer 2014 May 15;120(10):1482-90. Epub 2014 Feb 5 doi: 10.1002/cncr.28599. PMID: 24500602 Free PMC Article

Comprehensive lipidome profiling of isogenic primary and metastatic colon adenocarcinoma cell lines.

Fhaner CJ, Liu S, Ji H, Simpson RJ, Reid GE
Anal Chem 2012 Nov 6;84(21):8917-26. Epub 2012 Oct 10 doi: 10.1021/ac302154g. PMID: 23039336 Free PMC Article

Acute coronary syndrome associated with continuous 5-Fluorouracil infusion in a patient with metastatic colorectal cancer-a case report with a discussion on this clinical dilemma.

Paiva CE, Paiva BS, Garita R, Michelin OC, Okoshi K
J Gastrointest Cancer 2009;40(3-4):133-7. doi: 10.1007/s12029-009-9101-z. PMID: 19936641

Liver transplantation for metastatic colon adenocarcinoma: report of a case with 10 years of follow-up without recurrence.

Honoré C, Detry O, De Roover A, Meurisse M, Honoré P
Transpl Int 2003 Sep;16(9):692-3. Epub 2003 Jun 12 doi: 10.1007/s00147-003-0605-3. PMID: 12802483

An unusual presentation of metastatic colon cancer to the lung.

Zias EA, Owen RP, Borczuk A, Reichel J, Frater RW
Chest 1998 Jan;113(1):244-6. doi: 10.1378/chest.113.1.244. PMID: 9440600

See all (17)

Diagnosis

Hidden colon adenocarcinoma diagnosed from mouth metastasis: case report and literature review.

de Almeida Lança ML, Carvalho YR, Almeida JD, Kaminagakura E
World J Surg Oncol 2023 Mar 10;21(1):88. doi: 10.1186/s12957-023-02978-y. PMID: 36899349 Free PMC Article

Nodular vasculitis associated with lung adenocarcinoma.

Borges AS, Brasileiro A, Apetato M
An Bras Dermatol 2018 Nov/Dec;93(6):887-889. doi: 10.1590/abd1806-4841.20187741. PMID: 30484537 Free PMC Article

Technetium-bevacizumab in a patient with bone and lung metastatic colon adenocarcinoma.

Noguera EC, Palazzo E, Mayoraz MF, Diller A, Burgesser MV, Jaime A, Borello A, Avila R, Mondina JC
J Clin Oncol 2013 Apr 10;31(11):e170-2. Epub 2013 Mar 4 doi: 10.1200/JCO.2012.44.0099. PMID: 23460717

Metastatic Colon Adenocarcinoma Presenting as Left Preauricular Pain.

Matt LB, McGee SW
J Gastrointest Cancer 2012 Sep;43 Suppl 1:S251-3. doi: 10.1007/s12029-012-9410-5. PMID: 22766623

Metastatic colon adenocarcinoma mimicking herpes zoster.

Goodwin TL, Wren SM
J Am Coll Surg 2007 Oct;205(4):625. Epub 2007 Jul 20 doi: 10.1016/j.jamcollsurg.2007.01.073. PMID: 17903740

See all (33)

Therapy

Sclerodermatous eruption in a patient with metastatic colon cancer treated with an FLT3/CDK inhibitor.

Zou H, Deirawan H, Uprety D, Daveluy S
Australas J Dermatol 2023 Aug;64(3):e272-e274. Epub 2023 May 31 doi: 10.1111/ajd.14093. PMID: 37255338

Long-term response to sintilimab, bevacizumab and chemotherapy in heavily pretreated microsatellite stable colon cancer.

Cui Z, Wang Q, Deng M, Meng E, Liu S, Niu B, Han Q
Immunotherapy 2023 Feb;15(3):127-133. Epub 2023 Feb 1 doi: 10.2217/imt-2022-0058. PMID: 36722149

Vemurafenib-induced histiocytoid neutrophilic panniculitis simulating myeloid leukaemia cutis.

Richarz NA, Puig L, Pérez N, Cuadra-Urteaga J, Elez E, Fernández-Figueras MT
Cancer Biol Ther 2019;20(3):237-239. Epub 2018 Nov 14 doi: 10.1080/15384047.2018.1529113. PMID: 30426827 Free PMC Article

Disseminated intravascular coagulation and immune hemolytic anemia, possibly Evans syndrome, after oxaliplatin and bevacizumab infusion for metastatic colon adenocarcinoma: a case report and literature review.

Meng L, Romano A, Smith E, Macik G, Grosh WW
Clin Colorectal Cancer 2015 Mar;14(1):e1-3. Epub 2014 Nov 15 doi: 10.1016/j.clcc.2014.11.005. PMID: 25600448

Expressing human interleukin-15 from oncolytic vesicular stomatitis virus improves survival in a murine metastatic colon adenocarcinoma model through the enhancement of anti-tumor immunity.

Stephenson KB, Barra NG, Davies E, Ashkar AA, Lichty BD
Cancer Gene Ther 2012 Apr;19(4):238-46. Epub 2011 Dec 9 doi: 10.1038/cgt.2011.81. PMID: 22158521

See all (13)

Prognosis

Simultaneous occurrence of IgG4-related Tubulointerstitial nephritis and colon adenocarcinoma with hepatic metastasis: a case report and literature review.

Gou SJ, Xue LJ, Hu ZX
BMC Nephrol 2019 Jan 16;20(1):23. doi: 10.1186/s12882-019-1205-5. PMID: 30651091 Free PMC Article

Nodular vasculitis associated with lung adenocarcinoma.

Borges AS, Brasileiro A, Apetato M
An Bras Dermatol 2018 Nov/Dec;93(6):887-889. doi: 10.1590/abd1806-4841.20187741. PMID: 30484537 Free PMC Article

Mutational analysis and clinical correlation of metastatic colorectal cancer.

Metastatic Colon Adenocarcinoma Presenting as Left Preauricular Pain.

Matt LB, McGee SW
J Gastrointest Cancer 2012 Sep;43 Suppl 1:S251-3. doi: 10.1007/s12029-012-9410-5. PMID: 22766623

Liver transplantation for metastatic colon adenocarcinoma: report of a case with 10 years of follow-up without recurrence.

Honoré C, Detry O, De Roover A, Meurisse M, Honoré P
Transpl Int 2003 Sep;16(9):692-3. Epub 2003 Jun 12 doi: 10.1007/s00147-003-0605-3. PMID: 12802483

See all (19)

Clinical prediction guides

Genetic profiling of metastatic colon adenocarcinoma in Iranian patients: Insights into pathogenic variants and tumor characteristics.

Boroonsara P, Esfehani RJ, Kermani AT, Shakour N
Cancer Genet 2024 Nov;288-289:133-136. Epub 2024 Nov 9 doi: 10.1016/j.cancergen.2024.11.003. PMID: 39566319

Hidden colon adenocarcinoma diagnosed from mouth metastasis: case report and literature review.

de Almeida Lança ML, Carvalho YR, Almeida JD, Kaminagakura E
World J Surg Oncol 2023 Mar 10;21(1):88. doi: 10.1186/s12957-023-02978-y. PMID: 36899349 Free PMC Article

Metastatic colon adenocarcinoma has a significantly elevated expression of IL-10 compared with primary colon adenocarcinoma tumors.

Townsend MH, Felsted AM, Piccolo SR, Robison RA, O'Neill KL
Cancer Biol Ther 2018;19(10):913-920. Epub 2018 May 10 doi: 10.1080/15384047.2017.1360453. PMID: 28812429 Free PMC Article

Surgical management of extensive peristomal pyoderma gangrenosum associated with colon cancer.

Ishikawa K, Minamimoto T, Mizuki T, Furukawa H
J Wound Ostomy Continence Nurs 2015 Jan-Feb;42(1):102-5. doi: 10.1097/WON.0000000000000098. PMID: 25549316

Comprehensive lipidome profiling of isogenic primary and metastatic colon adenocarcinoma cell lines.

Fhaner CJ, Liu S, Ji H, Simpson RJ, Reid GE
Anal Chem 2012 Nov 6;84(21):8917-26. Epub 2012 Oct 10 doi: 10.1021/ac302154g. PMID: 23039336 Free PMC Article

See all (21)

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