Expression profiling by array Genome variation profiling by array Genome variation profiling by genome tiling array
Summary
Soybean cultivars RCAT-Angora & Harovinton, comparison of embryos at 30,40,50,60 & 70 days after pollination (dap) and seed development within each cultivar" Keywords: time course
Overall design
42 microarray slides GPL3015; 2 soybean cultivars, RCAT-Angora (with high seed isoflavonoid content)& Harovinton (with low seed isoflavonoid content); 2 technical reps for each time point (dye swap); 4 biological reps from 2 locations at London (L) & Delhi (D) Ontario & 2 consecutive growing seasons 2003 and 2004; 5 time points of 30, 40, 50, 60 & 70 dap for D04, L03, L04 and 4 time points of 30, 40, 50 and 70 dap for D03. In addition 2 slides for seed development confirmation D03 30 vs 70 dap RCAT-Angora and 2 for genomic comparison of RCAT-Angora & Harovinton were included. Slide data was analyzed in GeneSpringGX7.3, Agilent technologies, using background subtracted values. The ratio for RCAT/Hvtn was calculated from the 2 colour hybridization (same slide) and the relative expression for embryo development as a function of time (single channel approach) was calculated for each cultivar. The slide identities are L04 GSM94935 - 94944; genomic GSM95945-94946; L03 GSM94947 - 94956; D04 GSM94957 to 94966; D03 GSM94967 - 94976
Table 1: Cultivar ratio results (Merged normalized data of the ratio, RCAT divided by Harovinton, 4 biological reps merged in GeneSpringGX7.3, full soybean data set (18352), Average raw data intensities are published in the GSE4194 embryo development full data set, Gm-b10BB EST's had 4 replicate spots per array, these results are the average of 32 analyses) header descriptions
Group
A1, 733 EST's up regulated, minimum change 1.5x, greater in RCAT than Hvtn in any time point and average sVOL >10 in any condition; A2, 458 EST's down regulated, minimum change 1.5x, greater in Hvtn than RCAT in any time point and average sVOL >10 in any condition; B, 10337 EST's with very little change in ratio (less than 1.5x change) and average background intensity >10 in any condition; C ,6873 EST's with low average sVOL <10 in all times and both cultivars, these are lower than twice the background intensity and not included in the data mining
Systematic Name
Genbank
RCAT/Hvtn 30 DAP
RCAT/Hvtn 40 DAP
RCAT/Hvtn 50 DAP
RCAT/Hvtn 60 DAP
RCAT/Hvtn 70 DAP
Best match BlastX August 2004
Data table
Group
Systematic Name
Genbank
RCAT/Hvtn 30 DAP
RCAT/Hvtn 40 DAP
RCAT/Hvtn 50 DAP
RCAT/Hvtn 60 DAP
RCAT/Hvtn 70 DAP
Best match BlastX August 2004
B
Gm-b10BB-1
AW318030
1.29
1.04
1.1
1.01
0.88
EF1-a : ELONGATION FACTOR 1-ALPHA
B
Gm-b10BB-2
BE806777
1.36
1.34
1.1
0.98
1.31
PAL PHENYLALANINE AMMONIA-LYASE 1
B
Gm-b10BB-3
AI855764
1.15
0.93
1.17
1.19
0.99
CHS1 :CHALCONE SYNTHASE 1
B
Gm-b10BB-4
AW707011
1.08
1.06
1.12
1.15
1.07
CHS1 : Chalcone synthase gene 1
C
Gm-b10BB-5
L03352
1.3
1
1.07
1.06
1.07
Glycine max chalcone synthase (chs6) gene, complete cds
A1
Gm-b10BB-6
AI437793
1.16
1.5
1.52
0.98
2.55
CHALCONE SYNTHASE 7
A1
Gm-b10BB-7
AI441937
1.28
1.69
1.63
1.04
2.57
CHS8 CHALCONE SYNTHASE 8
B
Gm-b10BB-9
BG157194
1.16
0.97
1.02
1.4
1.18
CI :CHALCONE--FLAVONONE ISOMERASE
B
Gm-b10BB-10
BG157194
1.05
1.02
0.97
1.04
1.08
CI : CHALCONE--FLAVONONE ISOMERASE
B
Gm-b10BB-11
AI930858
1.17
0.89
1.02
1.22
1.07
CI : CHALCONE ISOMERASE
A1
Gm-b10BB-12
AI900038
1.09
1.01
1.02
1.26
2.12
NARINGENIN,2-OXOGLUTARATE 3-DIOXYGENASE
C
Gm-b10BB-13
AW277481
0.74
0.84
0.96
0.88
0.9
NARINGENIN,2-OXOGLUTARATE 3-DIOXYGENASE
B
Gm-b10BB-14
AW156539
0.76
0.89
1.05
0.8
0.85
Fols : FLAVONOL SYNTHASE
B
Gm-b10BB-15
BE059354
0.81
1.19
0.99
0.89
0.86
Fols : FLAVONOL SYNTHASE
B
Gm-b10BB-17
AW830233
1.1
1.01
1
1.18
1.01
F3'5'H :CYTOCHROME P450 71D9
B
Gm-b10BB-18
AW569417
1.23
0.94
0.99
1.43
1.1
F3'5'H :CYTOCHROME P450 71D8
A1
Gm-b10BB-19
BE805102
1.15
0.99
0.98
1.53
0.83
CYTOCHROME P450 71D8
B
Gm-b10BB-20
BG157080
1.02
0.87
1.04
1.3
0.92
F3'5'H :FLAVONOID 3', 5'-HYDROXYLASE LIKE PROTEIN.
C
Gm-b10BB-21
BG041082
1.17
0.99
0.97
0.97
0.82
FLAVONOID 3', 5'-HYDROXYLASE-LIKE PROTEIN.
C
Gm-b10BB-22
BF069512
0.75
1.05
1.1
1
0.86
FLAVONOID 3'-HYDROXYLASE
Total number of rows: 18352
Table truncated, full table size 3369 Kbytes.
Table 2: Embryo development results (merged embryo development, single channel approach,4 biological reps merged in GeneSpringGX7.3, full data set (18352) for cultivarsHarovinton (Hvtn) and RCAT - Angora (RCAT), Gm-b10BB EST's had 4 replicate spots per array, these results are the average of 32 analyses) header descriptions
Group
A, 5910 EST's with significant change over time & average background subtracted intensity >10 in any condition; B, 5570 EST's with very little change over time & average background subtracted intensity >10 in any condition; C, 6872 EST's with average background intensity <10 in all times and both cultivars, these are less than 2x above background and not included in data mining
Systematic name
Genbank
Normalized Hvtn 30 DAP
data normalized in GeneSpring, per chip to 50th percentile and per gene to median of the measurements of that gene, average of 8 measurements single spotted EST's*
sVOL Hvtn 30 DAP
background subtracted intensity, average of readings from 8 hybridizations*
Normalized Hvtn 40 DAP
data normalized in GeneSpring, per chip to 50th percentile and per gene to median of the measurements of that gene, average of 8 measurements single spotted EST's*
sVOL Hvtn 40 DAP
background subtracted intensity, average of readings from 8 hybridizations*
Normalized Hvtn 50 DAP
data normalized in GeneSpring, per chip to 50th percentile and per gene to median of the measurements of that gene, average of 8 measurements single spotted EST's*
sVOL Hvtn 50 DAP
background subtracted intensity, average of readings from 8 hybridizations*
Normalized Hvtn 60 DAP
data normalized in GeneSpring, per chip to 50th percentile and per gene to median of the measurements of that gene, average of 8 measurements single spotted EST's*
sVOL Hvtn 60 DAP
background subtracted intensity, average of readings from 8 hybridizations*
Normalized Hvtn 70 DAP
data normalized in GeneSpring, per chip to 50th percentile and per gene to median of the measurements of that gene, average of 8 measurements single spotted EST's*
sVOL Hvtn 70 DAP
background subtracted intensity, average of readings from 8 hybridizations*
Normalized RCAT 30 DAP
data normalized in GeneSpring, per chip to 50th percentile and per gene to median of the measurements of that gene, average of 8 measurements single spotted EST's*
sVOL RCAT 30 DAP
background subtracted intensity, average of readings from 8 hybridizations*
Normalized RCAT 40 DAP
data normalized in GeneSpring, per chip to 50th percentile and per gene to median of the measurements of that gene, average of 8 measurements single spotted EST's*
sVOL RCAT 40 DAP
background subtracted intensity, average of readings from 8 hybridizations*
Normalized RCAT 50 DAP
data normalized in GeneSpring, per chip to 50th percentile and per gene to median of the measurements of that gene, average of 8 measurements single spotted EST's*
sVOL RCAT 50 DAP
background subtracted intensity, average of readings from 8 hybridizations*
Normalized RCAT 60 DAP
data normalized in GeneSpring, per chip to 50th percentile and per gene to median of the measurements of that gene, average of 8 measurements single spotted EST's*
sVOL RCAT 60 DAP
background subtracted intensity, average of readings from 8 hybridizations*
Normalized RCAT 70 DAP
data normalized in GeneSpring, per chip to 50th percentile and per gene to median of the measurements of that gene, average of 8 measurements single spotted EST's*
sVOL RCAT 70 DAP
background subtracted intensity, average of readings from 8 hybridizations*
Best match BlastX August 2004
Data table
Group
Systematic name
Genbank
Normalized Hvtn 30 DAP
sVOL Hvtn 30 DAP
Normalized Hvtn 40 DAP
sVOL Hvtn 40 DAP
Normalized Hvtn 50 DAP
sVOL Hvtn 50 DAP
Normalized Hvtn 60 DAP
sVOL Hvtn 60 DAP
Normalized Hvtn 70 DAP
sVOL Hvtn 70 DAP
Normalized RCAT 30 DAP
sVOL RCAT 30 DAP
Normalized RCAT 40 DAP
sVOL RCAT 40 DAP
Normalized RCAT 50 DAP
sVOL RCAT 50 DAP
Normalized RCAT 60 DAP
sVOL RCAT 60 DAP
Normalized RCAT 70 DAP
sVOL RCAT 70 DAP
Best match BlastX August 2004
B
Gm-b10BB-1
AW318030
1.02
167
0.78
128
0.83
163
0.79
135
1.72
160
1.24
171
0.84
156
0.96
186
0.77
144
1.63
149
ELONGATION FACTOR 1-ALPHA
A
Gm-b10BB-2
BE806777
0.71
15
0.57
13
1.09
28
1.47
39
1.56
19
0.91
17
0.74
18
1.23
29
1.34
43
2.07
25
PHENYLALANINE AMMONIA-LYASE 1
A
Gm-b10BB-3
AI855764
0.71
11
0.53
8
0.61
11
0.64
12
0.89
9
0.84
12
0.47
9
0.72
12
0.72
13
0.87
9
CHALCONE SYNTHASE 1
A
Gm-b10BB-4
AW707011
0.7
10
0.46
7
0.61
10
0.52
9
0.83
8
0.75
10
0.45
8
0.68
11
0.59
10
0.81
8
CHALCONE SYNTHASE 1
C
Gm-b10BB-5
L03352
0.19
3
0.12
1
0.16
3
0.14
3
0.22
2
0.29
4
0.12
2
0.14
3
0.13
2
0.22
2
Glycine max chalcone synthase (chs6) gene, complete cds