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    vig vasa intronic gene [ Drosophila melanogaster (fruit fly) ]

    Gene ID: 34885, updated on 9-Dec-2024

    Summary

    Official Symbol
    vigprovided by FlyBase
    Official Full Name
    vasa intronic geneprovided by FlyBase
    Primary source
    FLYBASE:FBgn0024183
    Locus tag
    Dmel_CG4170
    See related
    AllianceGenome:FB:FBgn0024183
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Drosophila melanogaster
    Lineage
    Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota; Neoptera; Endopterygota; Diptera; Brachycera; Muscomorpha; Ephydroidea; Drosophilidae; Drosophila; Sophophora
    Also known as
    BG:DS00929.13; CG4170; Dmel\CG4170; EP(2)0812; Vig; VIG
    Summary
    Predicted to enable mRNA binding activity. Involved in heterochromatin organization and regulatory ncRNA-mediated post-transcriptional gene silencing. Located in cytoplasm; nucleus; and polytene chromosome puff. Part of RISC complex. Is expressed in several structures, including embryonic/larval midgut primordium; gut section; mesoderm; muscle cell; and visceral muscle primordium. Orthologous to several human genes including SERBP1 (SERPINE1 mRNA binding protein 1). [provided by Alliance of Genome Resources, Dec 2024]
    Orthologs
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    Genomic context

    See vig in Genome Data Viewer
    Location:
    35B10-35C1; 2-51 cM
    Exon count:
    5
    Annotation release Status Assembly Chr Location
    Release 6.54 current Release 6 plus ISO1 MT (GCF_000001215.4) 2L NT_033779.5 (15062931..15070316, complement)
    Release 5.57 previous assembly Release 5 (GCF_000001215.2) 2L NT_033779.4 (15062931..15070316, complement)

    Chromosome 2L - NT_033779.5Genomic Context describing neighboring genes Neighboring gene crinkled Neighboring gene uncharacterized protein Neighboring gene RNA polymerase II elongation factor Neighboring gene sisters on the loose Neighboring gene vasa Neighboring gene white walker Neighboring gene uncharacterized protein

    Genomic regions, transcripts, and products

    Interactions

    General gene information

    Gene Ontology Provided by FlyBase

    Function Evidence Code Pubs
    enables RNA binding  
    enables RNA binding  
    enables mRNA binding PubMed 
    enables protein binding PubMed 
    Component Evidence Code Pubs
    part_of RISC complex PubMed 
    part_of RISC complex PubMed 
    is_active_in cytoplasm  
    located_in cytoplasm PubMed 
    located_in cytosol PubMed 
    is_active_in nucleus  
    located_in nucleus PubMed 
    located_in polytene chromosome PubMed 
    located_in polytene chromosome puff PubMed 

    General protein information

    Preferred Names
    vasa intronic gene
    Names
    CG4170-PA
    CG4170-PB
    CG4170-PC
    CG4170-PD
    vig-PA
    vig-PB
    vig-PC
    vig-PD

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NT_033779.5 Reference assembly

      Range
      15062931..15070316 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_165102.2 → NP_723898.1  vasa intronic gene, isoform D [Drosophila melanogaster]

      See identical proteins and their annotated locations for NP_723898.1

      Status: REVIEWED

      UniProtKB/TrEMBL
      Q9V426
      Related
      FBpp0080277
      Conserved Domains (1) summary
      pfam04774
      Location:217 → 319
      HABP4_PAI-RBP1; Hyaluronan / mRNA binding family
    2. NM_165100.2 → NP_723896.1  vasa intronic gene, isoform B [Drosophila melanogaster]

      See identical proteins and their annotated locations for NP_723896.1

      Status: REVIEWED

      UniProtKB/TrEMBL
      Q9V426
      Related
      FBpp0080280
      Conserved Domains (1) summary
      pfam04774
      Location:217 → 319
      HABP4_PAI-RBP1; Hyaluronan / mRNA binding family
    3. NM_165101.2 → NP_723897.1  vasa intronic gene, isoform C [Drosophila melanogaster]

      See identical proteins and their annotated locations for NP_723897.1

      Status: REVIEWED

      UniProtKB/TrEMBL
      Q9V426
      Related
      FBpp0080278
      Conserved Domains (1) summary
      pfam04774
      Location:217 → 319
      HABP4_PAI-RBP1; Hyaluronan / mRNA binding family
    4. NM_078848.3 → NP_523572.1  vasa intronic gene, isoform A [Drosophila melanogaster]

      See identical proteins and their annotated locations for NP_523572.1

      Status: REVIEWED

      UniProtKB/TrEMBL
      Q9V426
      Related
      FBpp0080279
      Conserved Domains (1) summary
      pfam04774
      Location:217 → 319
      HABP4_PAI-RBP1; Hyaluronan / mRNA binding family
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