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    Pp1alpha-96A Protein phosphatase 1alpha at 96A [ Drosophila melanogaster (fruit fly) ]

    Gene ID: 42922, updated on 9-Dec-2024

    Summary

    Official Symbol
    Pp1alpha-96Aprovided by FlyBase
    Official Full Name
    Protein phosphatase 1alpha at 96Aprovided by FlyBase
    Primary source
    FLYBASE:FBgn0003134
    Locus tag
    Dmel_CG6593
    See related
    AllianceGenome:FB:FBgn0003134
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Drosophila melanogaster
    Lineage
    Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota; Neoptera; Endopterygota; Diptera; Brachycera; Muscomorpha; Ephydroidea; Drosophilidae; Drosophila; Sophophora
    Also known as
    96A; CG6593; Dmel\CG6593; DmPp1-96A; PP1; PP1 96A; PP1 alpha96a; Pp1-96A; PP1-96A; PP1A-96A; PP1alpha; pp1alpha-96A; PP1alpha-96A; pp1alpha96A; PP1alpha96A; PP1alpha[[1]]; PP1c; PP1c 96A
    Summary
    Predicted to enable protein serine/threonine phosphatase activity. Involved in negative regulation of smoothened signaling pathway and positive regulation of canonical Wnt signaling pathway. Located in cytoplasm. Part of protein phosphatase type 1 complex. Is expressed in adult head and organism. Orthologous to human PPP1CA (protein phosphatase 1 catalytic subunit alpha). [provided by Alliance of Genome Resources, Dec 2024]
    Orthologs
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    Genomic context

    See Pp1alpha-96A in Genome Data Viewer
    Location:
    96A5-96A5; 3-85 cM
    Exon count:
    5
    Annotation release Status Assembly Chr Location
    Release 6.54 current Release 6 plus ISO1 MT (GCF_000001215.4) 3R NT_033777.3 (24518270..24522331)
    Release 5.57 previous assembly Release 5 (GCF_000001215.2) 3R NT_033777.2 (20343992..20348053)

    Chromosome 3R - NT_033777.3Genomic Context describing neighboring genes Neighboring gene nicotinic Acetylcholine Receptor beta2 Neighboring gene DZIP1 Neighboring gene antisense RNA:CR44021 Neighboring gene uncharacterized protein Neighboring gene Juvenile hormone binding protein 12

    Genomic regions, transcripts, and products

    Bibliography

    Interactions

    General gene information

    Gene Ontology Provided by FlyBase

    Component Evidence Code Pubs
    located_in cytoplasm PubMed 
    is_active_in cytoplasm  
    is_active_in nucleus  
    part_of protein phosphatase type 1 complex PubMed 

    General protein information

    Preferred Names
    protein phosphatase 1alpha at 96A
    Names
    CG6593-PA
    CG6593-PB
    Pp1alpha-96A-PA
    Pp1alpha-96A-PB
    protein phosphatase 1
    NP_001262919.1
    NP_524484.1

    NCBI Reference Sequences (RefSeq)

    NEW Try the new Transcript table

    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NT_033777.3 Reference assembly

      Range
      24518270..24522331
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_001275990.1 → NP_001262919.1  protein phosphatase 1alpha at 96A, isoform B [Drosophila melanogaster]

      See identical proteins and their annotated locations for NP_001262919.1

      Status: REVIEWED

      UniProtKB/Swiss-Prot
      P48461, Q5U0Y2, Q9VC69
      UniProtKB/TrEMBL
      A0A0B4KHS9, C0MKX3
      Conserved Domains (1) summary
      cd07414
      Location:6 → 296
      MPP_PP1_PPKL; PP1, PPKL (PP1 and kelch-like) enzymes, and related proteins, metallophosphatase domain
    2. NM_079760.3 → NP_524484.1  protein phosphatase 1alpha at 96A, isoform A [Drosophila melanogaster]

      See identical proteins and their annotated locations for NP_524484.1

      Status: REVIEWED

      UniProtKB/Swiss-Prot
      P48461, Q5U0Y2, Q9VC69
      UniProtKB/TrEMBL
      A0A0B4KHS9, C0MKX3
      Related
      FBpp0084026
      Conserved Domains (1) summary
      cd07414
      Location:6 → 296
      MPP_PP1_PPKL; PP1, PPKL (PP1 and kelch-like) enzymes, and related proteins, metallophosphatase domain
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