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    MED27 Mediator complex subunit 27 [ Drosophila melanogaster (fruit fly) ]

    Gene ID: 40696, updated on 9-Dec-2024

    Summary

    Official Symbol
    MED27provided by FlyBase
    Official Full Name
    Mediator complex subunit 27provided by FlyBase
    Primary source
    FLYBASE:FBgn0037359
    Locus tag
    Dmel_CG1245
    See related
    AllianceGenome:FB:FBgn0037359
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Drosophila melanogaster
    Lineage
    Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota; Neoptera; Endopterygota; Diptera; Brachycera; Muscomorpha; Ephydroidea; Drosophilidae; Drosophila; Sophophora
    Also known as
    CG1245; CRSP34; dCrsp34; dCRSP34; Dmel\CG1245; dTRAP37; med27; Med27; Trap37
    Summary
    Predicted to enable transcription coactivator activity. Predicted to contribute to transcription coregulator activity. Predicted to be involved in regulation of transcription by RNA polymerase II. Located in nucleus. Part of mediator complex. Is expressed in several structures, including central brain primordium; ganglia; larval nervous system; and ventral nerve cord primordium. Orthologous to human MED27 (mediator complex subunit 27). [provided by Alliance of Genome Resources, Dec 2024]
    Orthologs
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    Genomic context

    See MED27 in Genome Data Viewer
    Location:
    83B8-83B8; 3-47.5 cM
    Exon count:
    3
    Annotation release Status Assembly Chr Location
    Release 6.54 current Release 6 plus ISO1 MT (GCF_000001215.4) 3R NT_033777.3 (5655139..5656336)
    Release 5.57 previous assembly Release 5 (GCF_000001215.2) 3R NT_033777.2 (1480861..1482058)

    Chromosome 3R - NT_033777.3Genomic Context describing neighboring genes Neighboring gene Secretory 23 Neighboring gene ethanol sensitive with low memory Neighboring gene uncharacterized protein Neighboring gene antisense RNA:CR44093 Neighboring gene WD repeat domain 33 Neighboring gene antisense RNA:CR46134

    Genomic regions, transcripts, and products

    Interactions

    General gene information

    Gene Ontology Provided by FlyBase

    Component Evidence Code Pubs
    part_of mediator complex  
    part_of mediator complex PubMed 
    part_of mediator complex  
    located_in nucleus PubMed 

    General protein information

    Preferred Names
    mediator complex subunit 27
    Names
    CG1245-PA
    MED27-PA

    NCBI Reference Sequences (RefSeq)

    NEW Try the new Transcript table

    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NT_033777.3 Reference assembly

      Range
      5655139..5656336
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_141312.4 → NP_649569.1  mediator complex subunit 27 [Drosophila melanogaster]

      See identical proteins and their annotated locations for NP_649569.1

      Status: REVIEWED

      UniProtKB/Swiss-Prot
      Q9VNG0
      Related
      FBpp0078361
      Conserved Domains (1) summary
      pfam11571
      Location:209 → 287
      Med27; Mediator complex subunit 27
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