MED14 Mediator complex subunit 14 [Drosophila melanogaster (fruit fly)] - Gene

Summary

Official Symbol: MED14provided by FlyBase
Official Full Name: Mediator complex subunit 14provided by FlyBase
Primary source: FLYBASE:FBgn0035145
Locus tag: Dmel_CG12031
See related: AllianceGenome:FB:FBgn0035145
Gene type: protein coding
RefSeq status: REVIEWED
Organism: Drosophila melanogaster
Lineage: Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota; Neoptera; Endopterygota; Diptera; Brachycera; Muscomorpha; Ephydroidea; Drosophilidae; Drosophila; Sophophora
Also known as: CG12031; Dmel\CG12031; dTRAP170; Med14; p160; Trap170
Summary: Enables transcription coregulator activity. Involved in regulation of transcription by RNA polymerase II. Part of core mediator complex and mediator complex. Is expressed in organism. Orthologous to human MED14 (mediator complex subunit 14). [provided by Alliance of Genome Resources, Jan 2025]
Orthologs: all
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Annotation release	Status	Assembly	Chr	Location
Release 6.54	current	Release 6 plus ISO1 MT (GCF_000001215.4)	3L	NT_037436.4 (593246..599239)
Release 5.57	previous assembly	Release 5 (GCF_000001215.2)	3L	NT_037436.3 (593246..599239)

Chromosome 3L - NT_037436.4 Genomic Context describing neighboring genes

Genomic Sequence:

Go to nucleotide: Graphics FASTA GenBank

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Products	Interactant	Other Gene	Complex	Source	Pubs	Description

Function	Evidence Code	Pubs
enables protein binding	IPI Inferred from Physical Interaction more info	PubMed
enables transcription coregulator activity	IBA Inferred from Biological aspect of Ancestor more info
enables transcription coregulator activity	IEA Inferred from Electronic Annotation more info
enables transcription coregulator activity	IMP Inferred from Mutant Phenotype more info	PubMed
enables transcription coregulator activity	ISS Inferred from Sequence or Structural Similarity more info	PubMed

Process	Evidence Code	Pubs
involved_in regulation of transcription by RNA polymerase II	IBA Inferred from Biological aspect of Ancestor more info
involved_in regulation of transcription by RNA polymerase II	IEA Inferred from Electronic Annotation more info
involved_in regulation of transcription by RNA polymerase II	IMP Inferred from Mutant Phenotype more info	PubMed
involved_in regulation of transcription initiation by RNA polymerase II	ISS Inferred from Sequence or Structural Similarity more info	PubMed

Component	Evidence Code	Pubs
part_of core mediator complex	IBA Inferred from Biological aspect of Ancestor more info
part_of core mediator complex	IPI Inferred from Physical Interaction more info	PubMed
part_of mediator complex	IBA Inferred from Biological aspect of Ancestor more info
part_of mediator complex	IEA Inferred from Electronic Annotation more info
part_of mediator complex	IMP Inferred from Mutant Phenotype more info	PubMed
part_of mediator complex	ISS Inferred from Sequence or Structural Similarity more info	PubMed

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The following sections contain reference sequences that belong to a specific genome build. Explain