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sau sauron [ Drosophila melanogaster (fruit fly) ]

Gene ID: 33402, updated on 27-Dec-2024

Summary

Official Symbol
sauprovided by FlyBase
Official Full Name
sauronprovided by FlyBase
Primary source
FLYBASE:FBgn0267378
Locus tag
Dmel_CG7085
See related
AllianceGenome:FB:FBgn0267378
Gene type
protein coding
RefSeq status
REVIEWED
Organism
Drosophila melanogaster
Lineage
Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota; Neoptera; Endopterygota; Diptera; Brachycera; Muscomorpha; Ephydroidea; Drosophilidae; Drosophila; Sophophora
Also known as
BcDNA:LD10657; BEST:LD28579; CG7085; dGOLPH3; Dmel\CG7085; GOLPH3; l(2)s5379; Rotini; rti; Rti; Sauron; Vps74
Summary
Enables phospholipid binding activity and small GTPase binding activity. Involved in several processes, including cytoskeleton-dependent cytokinesis; retrograde transport, vesicle recycling within Golgi; and spindle assembly. Located in Golgi membrane and cleavage furrow. Is expressed in several structures, including amnioserosa primordium; anterior endoderm anlage; embryonic head epidermis; epithelium; and spermatocyte. Orthologous to several human genes including GOLPH3 (golgi phosphoprotein 3). [provided by Alliance of Genome Resources, Dec 2024]
Orthologs
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Genomic context

See sau in Genome Data Viewer
Location:
22D4-22D4; 2-5 cM
Exon count:
5
Annotation release Status Assembly Chr Location
Release 6.54 current Release 6 plus ISO1 MT (GCF_000001215.4) 2L NT_033779.5 (2226342..2231099)
Release 5.57 previous assembly Release 5 (GCF_000001215.2) 2L NT_033779.4 (2226342..2231099)

Chromosome 2L - NT_033779.5Genomic Context describing neighboring genes Neighboring gene papi Neighboring gene antisense RNA:CR44114 Neighboring gene uncharacterized protein Neighboring gene Secretory 24CD Neighboring gene antisense RNA:CR44115 Neighboring gene Testis EndoG-Like 3

Genomic regions, transcripts, and products

Bibliography

GeneRIFs: Gene References Into Functions

What's a GeneRIF?

Interactions

General gene information

Gene Ontology Provided by FlyBase

Process Evidence Code Pubs
involved_in Golgi organization  
involved_in Golgi organization PubMed 
involved_in Golgi to plasma membrane protein transport  
involved_in Golgi vesicle budding  
involved_in actomyosin contractile ring assembly PubMed 
involved_in cleavage furrow formation PubMed 
involved_in male meiosis cytokinesis PubMed 
involved_in meiosis I cytokinesis PubMed 
involved_in meiosis II cytokinesis PubMed 
involved_in mitotic cytokinesis PubMed 
involved_in mitotic spindle assembly PubMed 
involved_in protein targeting to Golgi apparatus  
involved_in retrograde transport, vesicle recycling within Golgi PubMed 
involved_in retrograde vesicle-mediated transport, Golgi to endoplasmic reticulum  
involved_in spindle assembly PubMed 
involved_in spindle assembly involved in male meiosis PubMed 
involved_in symbiont entry into host cell PubMed 
Component Evidence Code Pubs
located_in Golgi apparatus PubMed 
is_active_in Golgi cisterna  
located_in Golgi cisterna  
located_in Golgi membrane PubMed 
located_in cleavage furrow PubMed 
is_active_in cytosol  
is_active_in trans-Golgi network  

General protein information

Preferred Names
sauron
Names
CG7085-PA
CG7085-PD
CG7085-PE
lethal (2) s5379
rotini
sau-PA
sau-PD
sau-PE

NCBI Reference Sequences (RefSeq)

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NT_033779.5 Reference assembly

    Range
    2226342..2231099
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NM_001014460.3 → NP_001014460.1  sauron, isoform D [Drosophila melanogaster]

    See identical proteins and their annotated locations for NP_001014460.1

    Status: REVIEWED

    UniProtKB/Swiss-Prot
    Q9VQ93
    Conserved Domains (1) summary
    pfam05719
    Location:58 → 267
    GPP34; Golgi phosphoprotein 3 (GPP34)
  2. NM_134814.5 → NP_608658.1  sauron, isoform A [Drosophila melanogaster]

    See identical proteins and their annotated locations for NP_608658.1

    Status: REVIEWED

    UniProtKB/Swiss-Prot
    Q9VQ93
    Related
    FBpp0100138
    Conserved Domains (1) summary
    pfam05719
    Location:58 → 267
    GPP34; Golgi phosphoprotein 3 (GPP34)
  3. NM_001032049.2 → NP_001027220.1  sauron, isoform E [Drosophila melanogaster]

    See identical proteins and their annotated locations for NP_001027220.1

    Status: REVIEWED

    UniProtKB/Swiss-Prot
    Q9VQ93
    Conserved Domains (1) summary
    pfam05719
    Location:58 → 267
    GPP34; Golgi phosphoprotein 3 (GPP34)
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