Similar studies for GEO DataSets (Select 200041574) - GEO DataSets

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Items: 20

Select item 2000415741.

MicroRNA expression profile of platelets in sickle cell disease

(Submitter supplied) Circulating platelets from Sickle cell disease (SCD) patients express distinct gene expression patterns that regulate function. The objective of this study is to identify a role of post-transcriptional regulation of the platelet transcriptional signaling by microRNAs.

Organism:: Homo sapiens

Type:: Non-coding RNA profiling by array

Platform:: GPL10850
43 Samples

Download data: TXT

Series

Accession:: GSE41574

ID:: 200041574

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Select item 2000415752.

Role of platelet micrornas in sickle cell disease

(Submitter supplied) This SuperSeries is composed of the SubSeries listed below.

Organism:: Homo sapiens

Type:: Expression profiling by array; Non-coding RNA profiling by array

Platforms:: GPL14550 GPL10850
53 Samples

Download data: TXT

Series

Accession:: GSE41575

ID:: 200041575

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Select item 2000415733.

Gene expression data in Meg-01 cells following transfection with platelet-enriched microRNA-1225-3p

(Submitter supplied) Platelets from sickle cell disease patients have differentially expressed microRNAs as compared to platelets from healthy control subjects. The objective of this study is to overexpress an upregulated miRNA,miR-1225-3p, in MEG01 cells to identify putative targets.

Organism:: Homo sapiens

Type:: Expression profiling by array

Platform:: GPL14550
10 Samples

Download data: TXT

Series

Accession:: GSE41573

ID:: 200041573

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Select item 2000367274.

MicroRNA Profiling in Mucosal Biopsies of Eosinophilic Esophagitis Patients Pre and Post Glucocorticoid Steroid Treatment and Relationship with mRNA Target Expression

(Submitter supplied) This SuperSeries is composed of the SubSeries listed below.

Organism:: Homo sapiens

Type:: Expression profiling by array; Expression profiling by RT-PCR

Platforms:: GPL13328 GPL6244
20 Samples

Download data: CEL

Series

Accession:: GSE36727

ID:: 200036727

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Select item 2000367265.

miRNA Profiling in mucosal biopsies of Eosinophilic Esophagitis patients pre and post glucocorticoid steroid treatment

(Submitter supplied) Eosinophlic esophagitis (EoE) is increasely recognized as an antigen-drived disorder. The goal of this study is to reveal the miRNA expression changes in EoE before and after a successful glucocorticoid steroid treatment.

Organism:: Homo sapiens

Type:: Expression profiling by RT-PCR

Platform:: GPL13328
10 Samples

Download data: TXT

Series

Accession:: GSE36726

ID:: 200036726

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Select item 2000367256.

Gene profiling in mucosal biopsies of Eosinophilic Esophagitis patients pre and post glucocorticoid steroid treatment

(Submitter supplied) Eosinophlic esophagitis (EoE) is increasely recognized as an antigen-drived disorder. The goal of this study is to reveal the gene expression changes in EoE before and after a successful glucocorticoid steroid treatment. We used microarrays to identify distinct genes involving the pathophysiology of EoE.

Organism:: Homo sapiens

Type:: Expression profiling by array

Platform:: GPL6244
10 Samples

Download data: CEL

Series

Accession:: GSE36725

ID:: 200036725

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Select item 2000804017.

Differential expression of plasma miRNAs in immune thrombocytopenia

(Submitter supplied) We investigated the expression profiles of plasma miRNAs in immune thrombocytopenia (ITP) patients. Peripheral blood plasma was used for Agilent miRNA expression microarray analysis to define miRNA profiles and to identify miRNAs with discriminatory levels for ITP and healthy controls. Results were further validated using quantitative realtime PCR on a larger cohort, enabling relative quantification of plasma miRNAs and defining miRNAs with diagnostic value for the disease.

Organism:: Homo sapiens

Type:: Non-coding RNA profiling by array

Platform:: GPL18402
16 Samples

Download data: TXT

Series

Accession:: GSE80401

ID:: 200080401

Select item 2000861868.

miRNA expression data before and after TGF-β treatment and Ago2-associated transcripts in lung fibroblasts

(Submitter supplied) This SuperSeries is composed of the SubSeries listed below.

Organism:: synthetic construct; Homo sapiens

Type:: Other; Non-coding RNA profiling by array

Platforms:: GPL21185 GPL8786
34 Samples

Download data: CEL

Series

Accession:: GSE86186

ID:: 200086186

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Select item 2000861859.

miRNA expression data in unstimulated and TGF-β1-stimulated lung fibroblasts

(Submitter supplied) Lung fibroblasts play an important role in extracellular matrix homeostasis and this process is mainly regulated by transforming growth factor-beta (TGF-β). Hence, lung fibroblasts are postulated to play a crucial role in aberrant lung tissue repair and remodeling, which is a main factor in lung diseases like COPD. In this study, the effect of TGF-β1 on the miRNA expression in parenchymal lung fibroblasts is investigated.

Organism:: Homo sapiens; synthetic construct

Type:: Non-coding RNA profiling by array

Platform:: GPL8786
18 Samples

Download data: CEL

Series

Accession:: GSE86185

ID:: 200086185

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Select item 20008618310.

mRNA expression profiling after Ago2-immunoprecipitation (IP) in unstimulated and TGF-β1-stimulated primary parenchymal lung fibroblasts of two control subjects

(Submitter supplied) To identify the target gene repertoire of miRNAs (i.e. the miRNA-targetome) of unstimulated and TGF-β1-stimulated primary parenchymal lung fibroblasts, Ago2-IP was performed followed by mRNA expression profiling.

Organism:: Homo sapiens

Type:: Other

Platform:: GPL21185
16 Samples

Download data: TXT

Series

Accession:: GSE86183

ID:: 200086183

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Select item 20005940111.

Gene expression profiles of rat enamel organs (secretory--stage and maturation stage)

(Submitter supplied) We conducted the genome-wide mRNA expression profiling in parallel with miRNA expression profiling using RNA samples extracted from rat incisor enamel organs, so as to refine the number of predicted gene targets for miRNA regulators.

Organism:: Rattus norvegicus

Type:: Expression profiling by array

Platform:: GPL6101
8 Samples

Download data: TXT

Series

Accession:: GSE59401

ID:: 200059401

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Select item 20004895912.

Mucosal expression profiling in (un)inflamed colon of patients with ulcerative colitis (UC)

(Submitter supplied) This SuperSeries is composed of the SubSeries listed below.

Organism:: synthetic construct; Homo sapiens

Type:: Expression profiling by array; Non-coding RNA profiling by array

Platforms:: GPL14613 GPL6244
48 Samples

Download data: CEL

Series

Accession:: GSE48959

ID:: 200048959

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Select item 20004895813.

Mucosal gene expression profiling in (un)inflamed colon of patients with ulcerative colitis (UC)

(Submitter supplied) In this study, we investigated if miRNA expression in UC mucosa is altered and correlated our findings with mucosal mRNA expression. Integration of mRNA and miRNA expression profiling may allow the identification of functional links between dysregulated miRNAs and their predicted target mRNA.

Organism:: Homo sapiens

Type:: Expression profiling by array

Platform:: GPL6244
21 Samples

Download data: CEL

Series

Accession:: GSE48958

ID:: 200048958

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Select item 20004895714.

Mucosal miRNA expression profiling in (un)inflamed colon of patients with ulcerative colitis (UC)

Organism:: synthetic construct; Homo sapiens

Type:: Non-coding RNA profiling by array

Platform:: GPL14613
27 Samples

Download data: CEL

Series

Accession:: GSE48957

ID:: 200048957

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Select item 20006958015.

Differential miRNA expression profiles betweenHBV-related HCC tumor versus non-tumor liver tissue

(Submitter supplied) miRNA played an important role in the process of carcinogenesis in HBV related hepatocellular carcinoma. Therefore, we performed miRNA microarray to evaluate the miRNAs that expressed differentially between HCC tumor versus non-tumor liver tissues.

Organism:: Homo sapiens

Type:: Non-coding RNA profiling by array

Platform:: GPL10850
10 Samples

Download data: TXT

Series

Accession:: GSE69580

ID:: 200069580

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Select item 20015062216.

miRNA Array of Transformed FTSECs [OCV versus CV & FAC versus UNT]

(Submitter supplied) We implementing a transcriptomic approach to identify global miRNA alterations in chronic iron exposed FTSECs. Chronic iron exposure in fallopian tube secretory epithelial cells (FTSECs) leads to alterations in oncogene expression and functional changes reminescent of early changes in ovarian cancer development (serous epithelial high grade ovarian tumors).

Organism:: Homo sapiens; synthetic construct

Type:: Non-coding RNA profiling by array

Platform:: GPL21572
12 Samples

Download data: CEL, CHP

Series

Accession:: GSE150622

ID:: 200150622

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Select item 20012490017.

Next generation sequencing (NGS) facilitates quantitative analysis of miRNA expression

(Submitter supplied) Using NGS approach we performed the search of multiple sclerosis-related miRNAs. We used PBMC as an informative and easily accessible biological material. To exclude bias in miRNA expression levels caused by disease modifying therapies, miRNA profiling was performed in treatment-naïve RRMS patients. Taking into account hypothetic gender specificity in disease pathogenesis we compared miRNA expression in RRMS patients and HCs separately for men and women. more...

Organism:: Homo sapiens

Type:: Non-coding RNA profiling by high throughput sequencing

Platform:: GPL15520
24 Samples

Download data: TXT

Series

Accession:: GSE124900

ID:: 200124900

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Select item 20006185618.

small RNA analysis in human platelets stored in blood bank

(Submitter supplied) Human platelets collected from healthy donors according to standard international protocols were pooled and stored at 4ºC during 7 days. The small RNA population changes across the days were evaluated by NGS aproach.

Organism:: Homo sapiens

Type:: Non-coding RNA profiling by high throughput sequencing

Platform:: GPL11154
6 Samples

Download data: TXT

Series

Accession:: GSE61856

ID:: 200061856

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Select item 20003103719.

Small RNA sequencing in normal and psoriatic skin

(Submitter supplied) We report the application of Illumina small RNA sequencing to normal human skin, as well as uninvolved and involved psoriatic skin. By obtaining over 600 million qualified reads from 20 healthy controls and 47 psoriasis biopsies (uninvolved/involved), we have generated a complete small RNA profile in normal and diseased human skin, with particular emphasis on miRNAs. We report the discovery of 284 putative novel miRNAs as well as 98 differentially expressed miRNAs in psoriatic skin.