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CG32264 uncharacterized protein [ Drosophila melanogaster (fruit fly) ]

Gene ID: 38438, updated on 4-Jan-2025

Summary

Official Symbol
CG32264provided by FlyBase
Official Full Name
uncharacterized proteinprovided by FlyBase
Primary source
FLYBASE:FBgn0052264
Locus tag
Dmel_CG32264
See related
AllianceGenome:FB:FBgn0052264
Gene type
protein coding
RefSeq status
REVIEWED
Organism
Drosophila melanogaster
Lineage
Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota; Neoptera; Endopterygota; Diptera; Brachycera; Muscomorpha; Ephydroidea; Drosophilidae; Drosophila; Sophophora
Also known as
CG10857; CG10860; CG12604; CG14978; Dmel\CG32264
Summary
Predicted to enable actin binding activity. Predicted to be involved in actin cytoskeleton organization. Predicted to be located in cytosol and nucleus. Is expressed in adult brain; anterior midgut primordium; embryonic/larval midgut; and posterior midgut primordium. Human ortholog(s) of this gene implicated in Parkinson's disease; artery disease (multiple); brain disease (multiple); and multiple sclerosis. Orthologous to several human genes including PHACTR1 (phosphatase and actin regulator 1). [provided by Alliance of Genome Resources, Jan 2025]
Orthologs
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Genomic context

See CG32264 in Genome Data Viewer
Location:
63E8-63F1; 3-9 cM
Exon count:
20
Annotation release Status Assembly Chr Location
Release 6.54 current Release 6 plus ISO1 MT (GCF_000001215.4) 3L NT_037436.4 (3714826..3806459, complement)
Release 5.57 previous assembly Release 5 (GCF_000001215.2) 3L NT_037436.3 (3714826..3806459, complement)

Chromosome 3L - NT_037436.4Genomic Context describing neighboring genes Neighboring gene long non-coding RNA:CR45675 Neighboring gene uncharacterized protein Neighboring gene pickpocket 27 Neighboring gene uncharacterized protein Neighboring gene uncharacterized protein Neighboring gene Integrator 10 Neighboring gene nutcracker

Genomic regions, transcripts, and products

Interactions

General gene information

Gene Ontology Provided by FlyBase

Function Evidence Code Pubs
enables actin binding  
enables actin binding  
Process Evidence Code Pubs
involved_in actin cytoskeleton organization  
involved_in actin cytoskeleton organization  
Component Evidence Code Pubs
located_in cytosol  
located_in nucleus  

General protein information

Preferred Names
uncharacterized protein
Names
CG32264-PB
CG32264-PD
CG32264-PE
CG32264-PG
CG32264-PI
CG32264-PJ
CG32264-PK
CG32264-PL
CG32264-PM

NCBI Reference Sequences (RefSeq)

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NT_037436.4 Reference assembly

    Range
    3714826..3806459 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NM_206268.4 → NP_995990.3  uncharacterized protein Dmel_CG32264, isoform K [Drosophila melanogaster]

    See identical proteins and their annotated locations for NP_995990.3

    Status: REVIEWED

    UniProtKB/TrEMBL
    E0R7R0
    Conserved Domains (2) summary
    smart00707
    Location:703 → 728
    RPEL; Repeat in Drosophila CG10860, human KIAA0680 and C. elegans F26H9.2
    pfam02755
    Location:149 → 171
    RPEL; RPEL repeat
  2. NM_001104025.2 → NP_001097495.2  uncharacterized protein Dmel_CG32264, isoform M [Drosophila melanogaster]

    See identical proteins and their annotated locations for NP_001097495.2

    Status: REVIEWED

    UniProtKB/TrEMBL
    A8JNJ8
    Conserved Domains (2) summary
    smart00707
    Location:808 → 833
    RPEL; Repeat in Drosophila CG10860, human KIAA0680 and C. elegans F26H9.2
    pfam02755
    Location:254 → 276
    RPEL; RPEL repeat
  3. NM_168037.2 → NP_728896.1  uncharacterized protein Dmel_CG32264, isoform I [Drosophila melanogaster]

    See identical proteins and their annotated locations for NP_728896.1

    Status: REVIEWED

    UniProtKB/TrEMBL
    Q9VZM9
    Related
    FBpp0300860
    Conserved Domains (2) summary
    smart00707
    Location:818 → 843
    RPEL; Repeat in Drosophila CG10860, human KIAA0680 and C. elegans F26H9.2
    pfam02755
    Location:254 → 276
    RPEL; RPEL repeat
  4. NM_001274446.1 → NP_001261375.1  uncharacterized protein Dmel_CG32264, isoform L [Drosophila melanogaster]

    See identical proteins and their annotated locations for NP_001261375.1

    Status: REVIEWED

    UniProtKB/TrEMBL
    M9PE70
    Conserved Domains (2) summary
    smart00707
    Location:640 → 665
    RPEL; Repeat in Drosophila CG10860, human KIAA0680 and C. elegans F26H9.2
    pfam02755
    Location:86 → 108
    RPEL; RPEL repeat
  5. NM_001104024.2 → NP_001097494.1  uncharacterized protein Dmel_CG32264, isoform E [Drosophila melanogaster]

    See identical proteins and their annotated locations for NP_001097494.1

    Status: REVIEWED

    UniProtKB/TrEMBL
    Q7YU16
    Conserved Domains (2) summary
    smart00707
    Location:879 → 904
    RPEL; Repeat in Drosophila CG10860, human KIAA0680 and C. elegans F26H9.2
    pfam02755
    Location:325 → 347
    RPEL; RPEL repeat
  6. NM_168038.2 → NP_728897.1  uncharacterized protein Dmel_CG32264, isoform D [Drosophila melanogaster]

    See identical proteins and their annotated locations for NP_728897.1

    Status: REVIEWED

    UniProtKB/TrEMBL
    Q9VZN0
    Related
    FBpp0073043
    Conserved Domains (2) summary
    smart00707
    Location:889 → 914
    RPEL; Repeat in Drosophila CG10860, human KIAA0680 and C. elegans F26H9.2
    pfam02755
    Location:325 → 347
    RPEL; RPEL repeat
  7. NM_001259678.1 → NP_001246607.1  uncharacterized protein Dmel_CG32264, isoform J [Drosophila melanogaster]

    See identical proteins and their annotated locations for NP_001246607.1

    Status: REVIEWED

    UniProtKB/TrEMBL
    D4G7A5
    Conserved Domains (1) summary
    smart00707
    Location:390 → 415
    RPEL; Repeat in Drosophila CG10860, human KIAA0680 and C. elegans F26H9.2
  8. NM_001202114.1 → NP_001189043.1  uncharacterized protein Dmel_CG32264, isoform G [Drosophila melanogaster]

    See identical proteins and their annotated locations for NP_001189043.1

    Status: REVIEWED

    UniProtKB/TrEMBL
    M9MRV3
    Conserved Domains (1) summary
    smart00707
    Location:345 → 370
    RPEL; Repeat in Drosophila CG10860, human KIAA0680 and C. elegans F26H9.2
  9. NM_168039.3 → NP_728898.1  uncharacterized protein Dmel_CG32264, isoform B [Drosophila melanogaster]

    See identical proteins and their annotated locations for NP_728898.1

    Status: REVIEWED

    UniProtKB/TrEMBL
    Q8SZJ7, Q9VZN2
    Related
    FBpp0073044
    Conserved Domains (1) summary
    smart00707
    Location:671 → 696
    RPEL; Repeat in Drosophila CG10860, human KIAA0680 and C. elegans F26H9.2
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