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Pp1-13C Protein phosphatase 1 at 13C [ Drosophila melanogaster (fruit fly) ]

Gene ID: 48531, updated on 4-Jan-2025

Summary

Official Symbol
Pp1-13Cprovided by FlyBase
Official Full Name
Protein phosphatase 1 at 13Cprovided by FlyBase
Primary source
FLYBASE:FBgn0003132
Locus tag
Dmel_CG9156
See related
AllianceGenome:FB:FBgn0003132
Gene type
protein coding
RefSeq status
REVIEWED
Organism
Drosophila melanogaster
Lineage
Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota; Neoptera; Endopterygota; Diptera; Brachycera; Muscomorpha; Ephydroidea; Drosophilidae; Drosophila; Sophophora
Also known as
13C; CG9156; Dmel\CG9156; DmPp1-13C; Pp1; PP1; PP1 13C; PP1 beta13c; pp1-13C; PP1-13C; PP13C; PP1alpha-13C; PP1alpha13C; PP1c
Summary
Enables protein serine/threonine phosphatase activity. Involved in negative regulation of BMP signaling pathway and negative regulation of smoothened signaling pathway. Part of protein phosphatase type 1 complex. Is expressed in adult heart; spermatozoon; and testis. Orthologous to human PPP1CA (protein phosphatase 1 catalytic subunit alpha). [provided by Alliance of Genome Resources, Jan 2025]
Orthologs
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Genomic context

See Pp1-13C in Genome Data Viewer
Location:
13B9-13B9; 1-50 cM
Exon count:
2
Annotation release Status Assembly Chr Location
Release 6.54 current Release 6 plus ISO1 MT (GCF_000001215.4) X NC_004354.4 (15359101..15361061, complement)
Release 5.57 previous assembly Release 5 (GCF_000001215.2) X NC_004354.3 (15253134..15255094, complement)

Chromosome X - NC_004354.4Genomic Context describing neighboring genes Neighboring gene uncharacterized protein Neighboring gene pre-mRNA processing factor 5 Neighboring gene abnormal chemosensory jump 6 Neighboring gene uncharacterized protein Neighboring gene Cyclic nucleotide-gated ion channel-like

Genomic regions, transcripts, and products

Interactions

General gene information

Gene Ontology Provided by FlyBase

Component Evidence Code Pubs
is_active_in cytoplasm  
is_active_in nucleus  
part_of protein phosphatase type 1 complex PubMed 

General protein information

Preferred Names
protein phosphatase 1 at 13C
Names
CG9156-PA
Pp1-13C-PA
protein phosphatase 1
protein phosphatase 1 13C
NP_524921.1

NCBI Reference Sequences (RefSeq)

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NC_004354.4 Reference assembly

    Range
    15359101..15361061 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NM_080182.3 → NP_524921.1  protein phosphatase 1 at 13C [Drosophila melanogaster]

    See identical proteins and their annotated locations for NP_524921.1

    Status: REVIEWED

    UniProtKB/Swiss-Prot
    Q05547, Q9VXW0
    UniProtKB/TrEMBL
    B4F4X2, C0MKX3
    Related
    FBpp0073834
    Conserved Domains (2) summary
    PTZ00480
    Location:5 → 299
    PTZ00480; serine/threonine-protein phosphatase; Provisional
    cd07414
    Location:6 → 296
    MPP_PP1_PPKL; PP1, PPKL (PP1 and kelch-like) enzymes, and related proteins, metallophosphatase domain
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