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Sample GSM7871461 Query DataSets for GSM7871461
Status Public on Oct 30, 2024
Title Hippocampus_rTg4510_WT [204018770003_R01C02]
Sample type genomic
 
Source name Hippocampus
Organism Mus musculus
Characteristics tissue: Hippocampus
externalsampleid: rTg4510_P5
Sex: F
dob: 9/8/2015
dod: 5/10/2016
agedays: 245
mousestrain: Mixed
ad_model: rTg4510
genotype: WT
Treatment protocol Mice were terminally anaesthetized with pentobarbital (intraperitoneal injection) and transcardially perfused with phosphate-buffered saline (PBS). The entorhinal cortex was dissected from the left brain hemisphere on wet ice and snap-frozen on dry ice for subsequent analysis
Growth protocol Animals were housed under standard conditions (constant temperature and humidity) with a 12h light/dark cycle in individually ventilated cages, with free access to food (Teklad irradiated global rodent diet (Envigo, United Kingdom)) and water.
Extracted molecule genomic DNA
Extraction protocol Genomic DNA from all samples was isolated from the entorhinal cortex or hippocampus using the AllPrep DNA/RNA Mini Kit (Qiagen)
Label Cy3, Cy5
Label protocol DNA methylation was measured using the the Mammalian Methylation Array (HorvathMammalMethylChip4, GEO: GPL28271)
 
Hybridization protocol Not provided
Scan protocol Illumina HiScan
Data processing Normalized Average Beta calculated using the SeSame package in R
 
Submission date Oct 30, 2023
Last update date Oct 30, 2024
Contact name Emma Walker
E-mail(s) [email protected]
Organization name University of Exeter
Street address RILD Barrack Rd
City Exeter
ZIP/Postal code EX2 5DW
Country United Kingdom
 
Platform ID GPL28271
Series (2)
GSE246559 Methylomic signatures of tau and beta amyloid in transgenic mouse models of Alzheimer’s disease neuropathology [HorvathMammalMethylChip40 Methylation Beadchip]
GSE246561 Methylomic signatures of tau and beta amyloid in transgenic mouse models of Alzheimer’s disease neuropathology

Data table header descriptions
ID_REF
VALUE Normalized Average Beta values

Data table
ID_REF VALUE
cg00001364 0.773931719250391
cg00001582 0.0660757084368986
cg00002920 0.539286351038805
cg00003994 0.0612147785148574
cg00004555 0.199692815857727
cg00005271 0.810453381413541
cg00006213 0.798668583141948
cg00010926 0.941027740855466
cg00010977 0.933775492511577
cg00013247 0.645886908161111
cg00014011 0.232780443156619
cg00015319 0.120115422516831
cg00016215 0.56575804584995
cg00017571 0.927637197312743
cg00019068 0.942811535671578
cg00021588 0.944993461929969
cg00022035 0.786976534751141
cg00027030 0.949846406457429
cg00029553 0.935860662222584
cg00029755 0.551362792867383

Total number of rows: 23633

Table truncated, full table size 671 Kbytes.




Supplementary file Size Download File type/resource
GSM7871461_204018770003_R01C02_Grn.idat.gz 378.8 Kb (ftp)(http) IDAT
GSM7871461_204018770003_R01C02_Red.idat.gz 382.5 Kb (ftp)(http) IDAT

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