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Sample GSM7871362 Query DataSets for GSM7871362
Status Public on Oct 30, 2024
Title Cortex Entorhinalis_rTg4510_TG [204027420007_R03C01]
Sample type genomic
 
Source name Cortex Entorhinalis
Organism Mus musculus
Characteristics tissue: Cortex Entorhinalis
externalsampleid: rTg4510_M18
Sex: F
dob: 12/8/2015
dod: 6/7/2016
agedays: 182
mousestrain: Mixed
ad_model: rTg4510
genotype: TG
Treatment protocol Mice were terminally anaesthetized with pentobarbital (intraperitoneal injection) and transcardially perfused with phosphate-buffered saline (PBS). The entorhinal cortex was dissected from the left brain hemisphere on wet ice and snap-frozen on dry ice for subsequent analysis
Growth protocol Animals were housed under standard conditions (constant temperature and humidity) with a 12h light/dark cycle in individually ventilated cages, with free access to food (Teklad irradiated global rodent diet (Envigo, United Kingdom)) and water.
Extracted molecule genomic DNA
Extraction protocol Genomic DNA from all samples was isolated from the entorhinal cortex or hippocampus using the AllPrep DNA/RNA Mini Kit (Qiagen)
Label Cy3, Cy5
Label protocol DNA methylation was measured using the the Mammalian Methylation Array (HorvathMammalMethylChip4, GEO: GPL28271)
 
Hybridization protocol Not provided
Scan protocol Illumina HiScan
Data processing Normalized Average Beta calculated using the SeSame package in R
 
Submission date Oct 30, 2023
Last update date Oct 30, 2024
Contact name Emma Walker
E-mail(s) [email protected]
Organization name University of Exeter
Street address RILD Barrack Rd
City Exeter
ZIP/Postal code EX2 5DW
Country United Kingdom
 
Platform ID GPL28271
Series (2)
GSE246559 Methylomic signatures of tau and beta amyloid in transgenic mouse models of Alzheimer’s disease neuropathology [HorvathMammalMethylChip40 Methylation Beadchip]
GSE246561 Methylomic signatures of tau and beta amyloid in transgenic mouse models of Alzheimer’s disease neuropathology

Data table header descriptions
ID_REF
VALUE Normalized Average Beta values

Data table
ID_REF VALUE
cg00001364 0.840913055667024
cg00001582 0.072593300964594
cg00002920 0.690369099404713
cg00003994 0.0529359714493591
cg00004555 0.251260838415042
cg00005271 0.86035114793688
cg00006213 0.766158585608987
cg00010926 0.899193874846933
cg00010977 0.935299402584231
cg00013247 0.743524569852783
cg00014011 0.285069708230115
cg00015319 0.181266657765371
cg00016215 0.679480161233107
cg00017571 0.936724961350176
cg00019068 0.914033638962682
cg00021588 0.941542460685038
cg00022035 0.916731227412717
cg00027030 0.966302661764969
cg00029553 0.944757705351366
cg00029755 0.731758953334795

Total number of rows: 23633

Table truncated, full table size 671 Kbytes.




Supplementary file Size Download File type/resource
GSM7871362_204027420007_R03C01_Grn.idat.gz 381.8 Kb (ftp)(http) IDAT
GSM7871362_204027420007_R03C01_Red.idat.gz 382.4 Kb (ftp)(http) IDAT

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