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| Status |
Public on Sep 06, 2013 |
| Title |
Potentiation of regulatory T cell stability and function via a neuropilin-1:semaphorin-4a axis |
| Organism |
Mus musculus |
| Experiment type |
Expression profiling by array
|
| Summary |
Regulatory T cells (Treg) represent a critical immunoregulatory component of the immune system. The signals that maintain Treg stability and potentiate their function remain obscure. Here we show that the immune cell surface ligand semaphorin-4a (Sema4a)
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| Overall design |
Sema treated and NRP1 knock outs were compared to untreated wild type T cell controls
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| Contributor(s) |
Delgoffe GM, Woo S, Tunis ME, Gravano DM, Guy C, Bettini ML, Vogel P, Finkelstein D, Bonnevier J, Workman CJ, Vignali DA |
| Citation(s) |
23913274 |
| |
| Submission date |
Sep 27, 2012 |
| Last update date |
Feb 11, 2019 |
| Contact name |
David Finkelstein |
| E-mail(s) |
[email protected]
|
| Phone |
9014953931
|
| Organization name |
St Jude Children's Research Hospital
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| Department |
Computational Biology
|
| Street address |
332 N. Lauderdale St.
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| City |
Memphis |
| State/province |
TN |
| ZIP/Postal code |
38105 |
| Country |
USA |
| |
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| Platforms (2) |
| GPL1261 |
[Mouse430_2] Affymetrix Mouse Genome 430 2.0 Array |
| GPL11180 |
[HT_MG-430_PM] Affymetrix HT MG-430 PM Array Plate |
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| Samples (40)
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| Relations |
| BioProject |
PRJNA176124 |
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