|
| Status |
Public on May 03, 2012 |
| Title |
Effect of interleukin-1 and PDGF-DD on SMCs |
| Organism |
Rattus norvegicus |
| Experiment type |
Expression profiling by array
|
| Summary |
This experiment tests the hypothesis that interleukin-1 promotes SMC phenotypic modulation to a distinct inflammatory state relative to the growth factor PDGF-DD.
|
| |
|
| Overall design |
Cultured rat aortic smooth muscle cells were treated with IL-1b (2.5 ng/mL) or vehicle (0.1% BSA and 10 mM acetic acid) or PDGF-DD (30 ng/mL) or vehicle (0.01% BSA) for 24 hours prior to harvest (n=1).
|
| |
|
| Contributor(s) |
Owens GK, Alexander MR |
| Citation(s) |
22318995 |
| |
| Submission date |
Aug 01, 2011 |
| Last update date |
Jul 31, 2017 |
| Contact name |
Gary Owens |
| Organization name |
University of Virginia
|
| Department |
Molecular Physiology and Biological Physics
|
| Lab |
Gary Owens' Laboratory
|
| Street address |
415 Lane Road
|
| City |
Charlottesville |
| State/province |
VA |
| ZIP/Postal code |
22908 |
| Country |
USA |
| |
|
| Platforms (1) |
| GPL1355 |
[Rat230_2] Affymetrix Rat Genome 230 2.0 Array |
|
| Samples (4)
|
|
| Relations |
| BioProject |
PRJNA144729 |
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