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Status |
Public on May 01, 2011 |
Title |
Effect of pressure overload on cardiac gene expression in wild-type and CHIP(-/-) mice |
Organism |
Mus musculus |
Experiment type |
Expression profiling by array
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Summary |
Wild-type mice or mice lacking the expression of CHIP (Stub1) were subjected to either sham surgery (Sham) or trans-aortic banding (TAB). After one week, RNA was extracted from heart and run on the Agilent 4x44K gene expression array to look at differences in the cardiac transcriptional response to pressure overload-induced hypertrophy in the absence of CHIP.
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Overall design |
Four-condition experiment: WT vs. CHIP(-/-) with SHAM or TAB surgery. Biological replicates: 4 per condition.
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Contributor(s) |
Schisler JC, Zhang C, Patterson C |
Citation(s) |
23863712 |
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Submission date |
Sep 17, 2010 |
Last update date |
Jan 12, 2017 |
Contact name |
Jonathan C Schisler |
E-mail(s) |
[email protected]
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Phone |
919-843-8708
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Organization name |
The University of North Carolina at Chapel Hill
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Department |
McAllister Heart Institute
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Lab |
Schisler Lab
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Street address |
MBRB, Rm 2340C
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City |
Chapel Hill |
State/province |
NC |
ZIP/Postal code |
27599-7126 |
Country |
USA |
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Platforms (1) |
GPL7202 |
Agilent-014868 Whole Mouse Genome Microarray 4x44K G4122F (Probe Name version) |
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Samples (16)
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Relations |
BioProject |
PRJNA130189 |