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    chic chickadee [ Drosophila melanogaster (fruit fly) ]

    Gene ID: 33834, updated on 9-Dec-2024

    Summary

    Official Symbol
    chicprovided by FlyBase
    Official Full Name
    chickadeeprovided by FlyBase
    Primary source
    FLYBASE:FBgn0000308
    Locus tag
    Dmel_CG9553
    See related
    AllianceGenome:FB:FBgn0000308
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Drosophila melanogaster
    Lineage
    Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota; Neoptera; Endopterygota; Diptera; Brachycera; Muscomorpha; Ephydroidea; Drosophilidae; Drosophila; Sophophora
    Also known as
    CG9553; chi; Chi; Chic; ChicE1; D88; Dmel\CG9553; GH4; l(2)27/7; prof; profilin; sand
    Summary
    Predicted to enable actin monomer binding activity. Involved in several processes, including nervous system development; positive regulation of cell projection organization; and post-embryonic animal morphogenesis. Located in neuron projection and perinuclear region of cytoplasm. Is expressed in several structures, including adult heart; follicle cell; larval ventral nerve cord; nurse cell; and ovary. Used to study cardiomyopathy and myopathy. [provided by Alliance of Genome Resources, Dec 2024]
    Orthologs
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    Genomic context

    See chic in Genome Data Viewer
    Location:
    26A5-26B2; 2-18 cM
    Exon count:
    6
    Annotation release Status Assembly Chr Location
    Release 6.54 current Release 6 plus ISO1 MT (GCF_000001215.4) 2L NT_033779.5 (5972115..5981018, complement)
    Release 5.57 previous assembly Release 5 (GCF_000001215.2) 2L NT_033779.4 (5972115..5981018, complement)

    Chromosome 2L - NT_033779.5Genomic Context describing neighboring genes Neighboring gene antisense RNA:CR43465 Neighboring gene Uncoupling protein 4C Neighboring gene Uncoupling protein 4B Neighboring gene eukaryotic translation initiation factor 4A Neighboring gene infertile crescent

    Genomic regions, transcripts, and products

    Bibliography

    GeneRIFs: Gene References Into Functions

    What's a GeneRIF?

    Interactions

    General gene information

    Gene Ontology Provided by FlyBase

    Function Evidence Code Pubs
    enables actin binding  
    enables actin monomer binding  
    enables protein binding PubMed 
    Process Evidence Code Pubs
    involved_in actin filament organization PubMed 
    involved_in actin filament polymerization PubMed 
    involved_in actomyosin contractile ring assembly PubMed 
    involved_in brain development PubMed 
    involved_in brain development PubMed 
    involved_in cell morphogenesis PubMed 
    involved_in dorsal closure PubMed 
    involved_in histoblast morphogenesis PubMed 
    involved_in larval central nervous system remodeling PubMed 
    involved_in larval salivary gland morphogenesis PubMed 
    involved_in maintenance of protein location in cell PubMed 
    involved_in male germ-line stem cell population maintenance PubMed 
    involved_in mitotic cytokinesis PubMed 
    involved_in neuron remodeling PubMed 
    involved_in neuron remodeling PubMed 
    involved_in oocyte karyosome formation PubMed 
    involved_in ovarian nurse cell to oocyte transport PubMed 
    involved_in pole plasm oskar mRNA localization PubMed 
    involved_in positive regulation of axon extension involved in axon guidance PubMed 
    involved_in positive regulation of axon regeneration PubMed 
    involved_in positive regulation of filopodium assembly PubMed 
    involved_in sequestering of actin monomers  
    involved_in somatic stem cell population maintenance PubMed 
    involved_in wound healing PubMed 
    Component Evidence Code Pubs
    is_active_in cell cortex  
    located_in cytoplasm PubMed 
    located_in neuron projection PubMed 
    located_in perinuclear region of cytoplasm PubMed 

    General protein information

    Preferred Names
    chickadee
    Names
    CG9553-PA
    CG9553-PB
    CG9553-PC
    CG9553-PD
    CG9553-PE
    CG9553-PF
    DProfilin
    chic-PA
    chic-PB
    chic-PC
    chic-PD
    chic-PE
    chic-PF
    chicadee
    chickaddee
    profilin
    stranded

    NCBI Reference Sequences (RefSeq)

    NEW Try the new Transcript table

    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NT_033779.5 Reference assembly

      Range
      5972115..5981018 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_205913.3 → NP_995635.1  chickadee, isoform D [Drosophila melanogaster]

      See identical proteins and their annotated locations for NP_995635.1

      Status: REVIEWED

      UniProtKB/Swiss-Prot
      P25843, Q3YMV6, Q9VMJ9
      UniProtKB/TrEMBL
      M9NEU5
      Conserved Domains (1) summary
      smart00392
      Location:1 → 126
      PROF; Profilin
    2. NM_164667.2 → NP_723136.1  chickadee, isoform C [Drosophila melanogaster]

      See identical proteins and their annotated locations for NP_723136.1

      Status: REVIEWED

      UniProtKB/Swiss-Prot
      P25843, Q3YMV6, Q9VMJ9
      UniProtKB/TrEMBL
      M9NEU5
      Related
      FBpp0078865, FBtr0079234
      Conserved Domains (1) summary
      smart00392
      Location:1 → 126
      PROF; Profilin
    3. NM_134304.3 → NP_599131.1  chickadee, isoform B [Drosophila melanogaster]

      See identical proteins and their annotated locations for NP_599131.1

      Status: REVIEWED

      UniProtKB/Swiss-Prot
      P25843, Q3YMV6, Q9VMJ9
      UniProtKB/TrEMBL
      M9NEU5
      Related
      FBpp0078866
      Conserved Domains (1) summary
      smart00392
      Location:1 → 126
      PROF; Profilin
    4. NM_001258977.2 → NP_001245906.1  chickadee, isoform F [Drosophila melanogaster]

      See identical proteins and their annotated locations for NP_001245906.1

      Status: REVIEWED

      UniProtKB/Swiss-Prot
      P25843, Q3YMV6, Q9VMJ9
      UniProtKB/TrEMBL
      M9NEU5
      Conserved Domains (1) summary
      smart00392
      Location:1 → 126
      PROF; Profilin
    5. NM_057668.6 → NP_477016.1  chickadee, isoform A [Drosophila melanogaster]

      See identical proteins and their annotated locations for NP_477016.1

      Status: REVIEWED

      UniProtKB/Swiss-Prot
      P25843, Q3YMV6, Q9VMJ9
      UniProtKB/TrEMBL
      M9NEU5
      Related
      FBpp0078864
      Conserved Domains (1) summary
      smart00392
      Location:1 → 126
      PROF; Profilin
    6. NM_001258976.2 → NP_001245905.1  chickadee, isoform E [Drosophila melanogaster]

      See identical proteins and their annotated locations for NP_001245905.1

      Status: REVIEWED

      UniProtKB/Swiss-Prot
      P25843, Q3YMV6, Q9VMJ9
      UniProtKB/TrEMBL
      M9NEU5
      Conserved Domains (1) summary
      smart00392
      Location:1 → 126
      PROF; Profilin
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