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AnxB10 Annexin B10 [ Drosophila melanogaster (fruit fly) ]

Gene ID: 33019, updated on 4-Jan-2025

Summary

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Official Symbol
AnxB10provided by FlyBase
Official Full Name
Annexin B10provided by FlyBase
Primary source
FLYBASE:FBgn0000084
Locus tag
Dmel_CG9579
See related
AllianceGenome:FB:FBgn0000084
Gene type
protein coding
RefSeq status
REVIEWED
Organism
Drosophila melanogaster
Lineage
Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota; Neoptera; Endopterygota; Diptera; Brachycera; Muscomorpha; Ephydroidea; Drosophilidae; Drosophila; Sophophora
Also known as
Ann; AnnB10; annexin; Annx; AnnX; ANXB10; anxX; CG9579; Dmel\CG9579
Summary
Enables calcium-dependent phospholipid binding activity. Predicted to be located in membrane. Predicted to be active in several cellular components, including nucleus; plasma membrane; and vesicle membrane. Is expressed in several structures, including adult head; adult heart; embryonic head sensory system; embryonic/larval dorsal vessel; and sensory nervous system primordium. Orthologous to several human genes including ANXA8 (annexin A8) and ANXA8L1 (annexin A8 like 1). [provided by Alliance of Genome Resources, Jan 2025]
Orthologs
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Genomic context

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See AnxB10 in Genome Data Viewer
Location:
19C1-19C1; 1-64 cM
Exon count:
5
Annotation release Status Assembly Chr Location
Release 6.54 current Release 6 plus ISO1 MT (GCF_000001215.4) X NC_004354.4 (20171445..20173514, complement)
Release 5.57 previous assembly Release 5 (GCF_000001215.2) X NC_004354.3 (20065478..20067547, complement)

Chromosome X - NC_004354.4Genomic Context describing neighboring genes Neighboring gene PHD finger protein 7 Neighboring gene uncharacterized protein Neighboring gene uncharacterized protein Neighboring gene uncharacterized protein Neighboring gene Sperm-specific dynein intermediate chain 1 Neighboring gene pseudo

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. Structure of the Drosophila melanogaster annexin X gene. Benevolenskaya EV, et al. DNA Cell Biol, 1995 Apr. PMID 7710691
  2. Two novel annexins from Drosophila melanogaster. Cloning, characterization, and differential expression in development. Johnston PA, et al. J Biol Chem, 1990 Jul 5. PMID 2141610
  3. New gene evolution: little did we know. Long M, et al. Annu Rev Genet, 2013. PMID 24050177, Free PMC Article
  4. Cytoplasmic dynein intermediate-chain isoforms with different targeting properties created by tissue-specific alternative splicing. Nurminsky DI, et al. Mol Cell Biol, 1998 Nov. PMID 9774695, Free PMC Article
  5. Evolutionary biology. A plastic genome. Capy P. Nature, 1998 Dec 10. PMID 9859983

See all (68) citations in PubMed

GeneRIFs: Gene References Into Functions

Interactions

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Products Interactant Other Gene Complex Source Pubs Description

General gene information

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Homology

Gene Ontology Provided by FlyBase

Function Evidence Code Pubs
enables calcium ion binding IEA
Inferred from Electronic Annotation
more info
  
enables calcium-dependent phospholipid binding IBA
Inferred from Biological aspect of Ancestor
more info
  
enables calcium-dependent phospholipid binding IDA
Inferred from Direct Assay
more info
 PubMed 
enables calcium-dependent phospholipid binding IEA
Inferred from Electronic Annotation
more info
  
enables phosphatidylserine binding IBA
Inferred from Biological aspect of Ancestor
more info
  
Process Evidence Code Pubs
involved_in biological_process ND
No biological Data available
more info
  
Component Evidence Code Pubs
is_active_in cytoplasm IBA
Inferred from Biological aspect of Ancestor
more info
  
located_in membrane IC
Inferred by Curator
more info
 PubMed 
is_active_in nucleus IBA
Inferred from Biological aspect of Ancestor
more info
  
is_active_in plasma membrane IBA
Inferred from Biological aspect of Ancestor
more info
  
is_active_in vesicle membrane IBA
Inferred from Biological aspect of Ancestor
more info
  

General protein information

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Preferred Names
annexin B10
Names
AnxB10-PA
AnxB10-PB
CG9579-PA
CG9579-PB
annexin X
dAnnexin X

NCBI Reference Sequences (RefSeq)

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NC_004354.4 Reference assembly

    Range
    20171445..20173514 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NM_057267.4 → NP_476615.1  annexin B10, isoform A [Drosophila melanogaster]

    See identical proteins and their annotated locations for NP_476615.1

    Status: REVIEWED

    UniProtKB/Swiss-Prot
    P22465
    Related
    FBpp0070024
    Conserved Domains (1) summary
    pfam00191
    Location:19 → 84
    Annexin; Annexin

  2. NM_001169333.2 → NP_001162804.1  annexin B10, isoform B [Drosophila melanogaster]

    See identical proteins and their annotated locations for NP_001162804.1

    Status: REVIEWED

    UniProtKB/Swiss-Prot
    E1JJR8, E8NH50, P22465, Q27586, Q9W5W5
    Conserved Domains (1) summary
    pfam00191
    Location:19 → 84
    Annexin; Annexin
Nucleotide Protein
Heading Accession and Version
Protein Accession Links
GenPept Link UniProtKB Link
P22465.3 P22465

Gene LinkOut

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