U.S. flag

An official website of the United States government

Links from GEO Profiles

    • Showing Current items.

    Zif Zinc-finger protein [ Drosophila melanogaster (fruit fly) ]

    Gene ID: 40795, updated on 9-Dec-2024

    Summary

    Official Symbol
    Zifprovided by FlyBase
    Official Full Name
    Zinc-finger proteinprovided by FlyBase
    Primary source
    FLYBASE:FBgn0037446
    Locus tag
    Dmel_CG10267
    See related
    AllianceGenome:FB:FBgn0037446
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Drosophila melanogaster
    Lineage
    Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota; Neoptera; Endopterygota; Diptera; Brachycera; Muscomorpha; Ephydroidea; Drosophilidae; Drosophila; Sophophora
    Also known as
    anon-WO0118547.391; CC32; CG10267; Dmel\CG10267; zif; ZIF
    Summary
    Enables DNA-binding transcription repressor activity, RNA polymerase II-specific and sequence-specific DNA binding activity. Involved in establishment or maintenance of neuroblast polarity; larval lymph gland hemopoiesis; and negative regulation of transcription by RNA polymerase II. Located in nucleus. Is expressed in several structures, including embryonic/larval midgut; ganglia; gonad; larval neurons; and somatic precursor cell. [provided by Alliance of Genome Resources, Dec 2024]
    Orthologs
    NEW
    Try the new Gene table
    Try the new Transcript table

    Genomic context

    See Zif in Genome Data Viewer
    Location:
    83E8-83E8; 3-47.5 cM
    Exon count:
    5
    Annotation release Status Assembly Chr Location
    Release 6.54 current Release 6 plus ISO1 MT (GCF_000001215.4) 3R NT_033777.3 (6457088..6458822)
    Release 5.57 previous assembly Release 5 (GCF_000001215.2) 3R NT_033777.2 (2282810..2284544)

    Chromosome 3R - NT_033777.3Genomic Context describing neighboring genes Neighboring gene long non-coding RNA:CR44017 Neighboring gene grappa Neighboring gene mir-9375 stem loop Neighboring gene uncharacterized protein Neighboring gene neurochondrin Neighboring gene uncharacterized protein

    Genomic regions, transcripts, and products

    Interactions

    General gene information

    Gene Ontology Provided by FlyBase

    Component Evidence Code Pubs
    located_in nucleus PubMed 
    located_in nucleus  

    General protein information

    Preferred Names
    Zinc-finger protein
    Names
    CG10267-PA
    CG10267-PB
    CG10267-PC
    Zif-PA
    Zif-PB
    Zif-PC

    NCBI Reference Sequences (RefSeq)

    NEW Try the new Transcript table

    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NT_033777.3 Reference assembly

      Range
      6457088..6458822
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_001275390.1 → NP_001262319.1  Zinc-finger protein, isoform C [Drosophila melanogaster]

      See identical proteins and their annotated locations for NP_001262319.1

      Status: REVIEWED

      UniProtKB/TrEMBL
      Q9VI24
      Conserved Domains (4) summary
      COG5048
      Location:250 → 369
      COG5048; FOG: Zn-finger [General function prediction only]
      sd00017
      Location:253 → 273
      ZF_C2H2; C2H2 Zn finger [structural motif]
      pfam07776
      Location:9 → 87
      zf-AD; Zinc-finger associated domain (zf-AD)
      pfam13465
      Location:266 → 288
      zf-H2C2_2; Zinc-finger double domain
    2. NM_001202259.2 → NP_001189188.1  Zinc-finger protein, isoform B [Drosophila melanogaster]

      See identical proteins and their annotated locations for NP_001189188.1

      Status: REVIEWED

      UniProtKB/TrEMBL
      Q9VI24
      Conserved Domains (4) summary
      COG5048
      Location:250 → 369
      COG5048; FOG: Zn-finger [General function prediction only]
      sd00017
      Location:253 → 273
      ZF_C2H2; C2H2 Zn finger [structural motif]
      pfam07776
      Location:9 → 87
      zf-AD; Zinc-finger associated domain (zf-AD)
      pfam13465
      Location:266 → 288
      zf-H2C2_2; Zinc-finger double domain
    3. NM_141400.4 → NP_649657.1  Zinc-finger protein, isoform A [Drosophila melanogaster]

      See identical proteins and their annotated locations for NP_649657.1

      Status: REVIEWED

      UniProtKB/TrEMBL
      Q9VI24
      Related
      FBpp0081225
      Conserved Domains (4) summary
      COG5048
      Location:250 → 369
      COG5048; FOG: Zn-finger [General function prediction only]
      sd00017
      Location:253 → 273
      ZF_C2H2; C2H2 Zn finger [structural motif]
      pfam07776
      Location:9 → 87
      zf-AD; Zinc-finger associated domain (zf-AD)
      pfam13465
      Location:266 → 288
      zf-H2C2_2; Zinc-finger double domain
    External link. Please review our privacy policy.