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CG2120 uncharacterized protein [ Drosophila melanogaster (fruit fly) ]

Gene ID: 31737, updated on 4-Jan-2025

Summary

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Official Symbol
CG2120provided by FlyBase
Official Full Name
uncharacterized proteinprovided by FlyBase
Primary source
FLYBASE:FBgn0030005
Locus tag
Dmel_CG2120
See related
AllianceGenome:FB:FBgn0030005
Gene type
protein coding
RefSeq status
REVIEWED
Organism
Drosophila melanogaster
Lineage
Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota; Neoptera; Endopterygota; Diptera; Brachycera; Muscomorpha; Ephydroidea; Drosophilidae; Drosophila; Sophophora
Also known as
Dmel\CG2120
Summary
Predicted to enable DNA-binding transcription repressor activity, RNA polymerase II-specific and RNA polymerase II transcription regulatory region sequence-specific DNA binding activity. Predicted to be involved in negative regulation of transcription by RNA polymerase II. Predicted to be active in nucleus. Is expressed in embryonic hindgut and organism. [provided by Alliance of Genome Resources, Jan 2025]
Orthologs
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Genomic context

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See CG2120 in Genome Data Viewer
Location:
7D14-7D14; 1-22 cM
Exon count:
2
Annotation release Status Assembly Chr Location
Release 6.54 current Release 6 plus ISO1 MT (GCF_000001215.4) X NC_004354.4 (8135824..8137046)
Release 5.57 previous assembly Release 5 (GCF_000001215.2) X NC_004354.3 (8029857..8031079)

Chromosome X - NC_004354.4Genomic Context describing neighboring genes Neighboring gene cypher Neighboring gene uncharacterized protein Neighboring gene uncharacterized protein Neighboring gene Smad on X Neighboring gene uncharacterized protein Neighboring gene Phenylalanyl-tRNA synthetase, alpha-subunit

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. Predictive features of gene expression variation reveal mechanistic link with differential expression. Sigalova OM, et al. Mol Syst Biol, 2020 Aug. PMID 32767663, Free PMC Article
  2. Rapid and efficient cDNA library screening by self-ligation of inverse PCR products (SLIP). Hoskins RA, et al. Nucleic Acids Res, 2005 Dec 2. PMID 16326860, Free PMC Article
  3. Enteric bacterial infection in Drosophila induces whole-body alterations in metabolic gene expression independently of the immune deficiency signaling pathway. Deshpande R, et al. G3 (Bethesda), 2022 Nov 4. PMID 35781508, Free PMC Article
  4. A large-scale, in vivo transcription factor screen defines bivalent chromatin as a key property of regulatory factors mediating Drosophila wing development. Schertel C, et al. Genome Res, 2015 Apr. PMID 25568052, Free PMC Article
  5. Next-generation large-scale binary protein interaction network for Drosophila melanogaster. Tang HW, et al. Nat Commun, 2023 Apr 15. PMID 37061542, Free PMC Article

See all (25) citations in PubMed

GeneRIFs: Gene References Into Functions

Interactions

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Products Interactant Other Gene Complex Source Pubs Description

General gene information

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Homology

Gene Ontology Provided by FlyBase

Function Evidence Code Pubs
enables DNA-binding transcription factor activity, RNA polymerase II-specific IBA
Inferred from Biological aspect of Ancestor
more info
  
enables DNA-binding transcription repressor activity, RNA polymerase II-specific ISS
Inferred from Sequence or Structural Similarity
more info
  
enables RNA polymerase II transcription regulatory region sequence-specific DNA binding IBA
Inferred from Biological aspect of Ancestor
more info
  
enables sequence-specific DNA binding ISS
Inferred from Sequence or Structural Similarity
more info
  
Process Evidence Code Pubs
involved_in negative regulation of transcription by RNA polymerase II ISS
Inferred from Sequence or Structural Similarity
more info
  
involved_in regulation of transcription by RNA polymerase II IBA
Inferred from Biological aspect of Ancestor
more info
  
Component Evidence Code Pubs
is_active_in nucleus IBA
Inferred from Biological aspect of Ancestor
more info
  
located_in nucleus ISS
Inferred from Sequence or Structural Similarity
more info
  

General protein information

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Preferred Names
uncharacterized protein
Names
CG2120-PB

NCBI Reference Sequences (RefSeq)

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NC_004354.4 Reference assembly

    Range
    8135824..8137046
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NM_132218.3 → NP_572446.2  uncharacterized protein Dmel_CG2120 [Drosophila melanogaster]

    See identical proteins and their annotated locations for NP_572446.2

    Status: REVIEWED

    UniProtKB/TrEMBL
    Q0IGR3, Q9W3J7
    Conserved Domains (3) summary
    COG5048
    Location:151 → 264
    COG5048; FOG: Zn-finger [General function prediction only]
    sd00017
    Location:101 → 121
    ZF_C2H2; C2H2 Zn finger [structural motif]
    pfam13465
    Location:142 → 166
    zf-H2C2_2; Zinc-finger double domain
Nucleotide Protein
Heading Accession and Version
Protein Accession Links
GenPept Link UniProtKB Link
Q0IGR3 Q0IGR3

Gene LinkOut

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