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    ScsbetaG Succinyl-coenzyme A synthetase beta subunit, GDP-forming [ Drosophila melanogaster (fruit fly) ]

    Gene ID: 44001, updated on 9-Dec-2024

    Summary

    Official Symbol
    ScsbetaGprovided by FlyBase
    Official Full Name
    Succinyl-coenzyme A synthetase beta subunit, GDP-formingprovided by FlyBase
    Primary source
    FLYBASE:FBgn0029118
    Locus tag
    Dmel_CG10622
    See related
    AllianceGenome:FB:FBgn0029118
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Drosophila melanogaster
    Lineage
    Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota; Neoptera; Endopterygota; Diptera; Brachycera; Muscomorpha; Ephydroidea; Drosophilidae; Drosophila; Sophophora
    Also known as
    142911_at; CG10622; Dmel\CG10622; G-Sbeta; sucb; sucB; Sucb; SucB
    Summary
    Predicted to enable succinate-CoA ligase (GDP-forming) activity. Predicted to be involved in succinyl-CoA metabolic process and tricarboxylic acid cycle. Predicted to be part of succinate-CoA ligase complex (GDP-forming). Predicted to be active in mitochondrion. Is expressed in several structures, including Malpighian tubule primordium; adult head; embryonic/larval midgut; embryonic/larval midgut primordium; and hindgut proper primordium. Orthologous to human SUCLG2 (succinate-CoA ligase GDP-forming subunit beta). [provided by Alliance of Genome Resources, Dec 2024]
    Orthologs
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    Genomic context

    See ScsbetaG in Genome Data Viewer
    Location:
    64D3-64D3; 3-14 cM
    Exon count:
    4
    Annotation release Status Assembly Chr Location
    Release 6.54 current Release 6 plus ISO1 MT (GCF_000001215.4) 3L NT_037436.4 (5561701..5563691, complement)
    Release 5.57 previous assembly Release 5 (GCF_000001215.2) 3L NT_037436.3 (5554801..5556791, complement)

    Chromosome 3L - NT_037436.4Genomic Context describing neighboring genes Neighboring gene farmer Neighboring gene sinuous Neighboring gene severas Neighboring gene bc10

    Genomic regions, transcripts, and products

    Pathways from PubChem

    Interactions

    General gene information

    Gene Ontology Provided by FlyBase

    Function Evidence Code Pubs
    enables ATP binding  
    NOT enables succinate-CoA ligase (ADP-forming) activity  
    enables succinate-CoA ligase (GDP-forming) activity  
    enables succinate-CoA ligase (GDP-forming) activity  
    Process Evidence Code Pubs
    involved_in succinyl-CoA metabolic process  
    involved_in succinyl-CoA metabolic process  
    involved_in tricarboxylic acid cycle  
    involved_in tricarboxylic acid cycle  
    Component Evidence Code Pubs
    is_active_in mitochondrion  
    part_of succinate-CoA ligase complex  
    part_of succinate-CoA ligase complex (GDP-forming)  

    General protein information

    Preferred Names
    Succinyl-coenzyme A synthetase beta subunit, GDP-forming
    Names
    CG10622-PA
    CG10622-PC
    GTP-specific SCSbeta
    GTP-specific form of the succinyl-CoA synthetase beta subunit
    ScsbetaG-PA
    ScsbetaG-PC
    sucb
    succinyl CoA synthetase
    succinyl coenzyme A synthetase GDP-forming beta subunit
    NP_001286941.1
    NP_651963.1

    NCBI Reference Sequences (RefSeq)

    NEW Try the new Transcript table

    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NT_037436.4 Reference assembly

      Range
      5561701..5563691 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_143706.5 → NP_651963.1  Succinyl-coenzyme A synthetase beta subunit, GDP-forming, isoform A [Drosophila melanogaster]

      See identical proteins and their annotated locations for NP_651963.1

      Status: REVIEWED

      UniProtKB/TrEMBL
      Q9V470
      Related
      FBpp0076840
      Conserved Domains (3) summary
      PRK00696
      Location:24 → 416
      sucC; succinyl-CoA synthetase subunit beta; Provisional
      pfam00549
      Location:292 → 412
      Ligase_CoA; CoA-ligase
      cl17255
      Location:24 → 232
      ATP-grasp_4; ATP-grasp domain
    2. NM_001300012.1 → NP_001286941.1  Succinyl-coenzyme A synthetase beta subunit, GDP-forming, isoform C [Drosophila melanogaster]

      See identical proteins and their annotated locations for NP_001286941.1

      Status: REVIEWED

      UniProtKB/TrEMBL
      Q9V470
      Conserved Domains (3) summary
      PRK00696
      Location:24 → 416
      sucC; succinyl-CoA synthetase subunit beta; Provisional
      pfam00549
      Location:292 → 412
      Ligase_CoA; CoA-ligase
      cl17255
      Location:24 → 232
      ATP-grasp_4; ATP-grasp domain
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