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    Arl2 ADP ribosylation factor-like 2 [ Drosophila melanogaster (fruit fly) ]

    Gene ID: 40993, updated on 9-Dec-2024

    Summary

    Official Symbol
    Arl2provided by FlyBase
    Official Full Name
    ADP ribosylation factor-like 2provided by FlyBase
    Primary source
    FLYBASE:FBgn0004908
    Locus tag
    Dmel_CG7435
    See related
    AllianceGenome:FB:FBgn0004908
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Drosophila melanogaster
    Lineage
    Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota; Neoptera; Endopterygota; Diptera; Brachycera; Muscomorpha; Ephydroidea; Drosophilidae; Drosophila; Sophophora
    Also known as
    Arf; Arf84D; Arf84F; arl2; ARL2; Arl84F; CG 7435; CG7435; Dm Arf84F; Dmel\CG7435; Q06849
    Summary
    Predicted to enable GTP binding activity and GTPase activity. Involved in establishment of mitotic spindle orientation and establishment or maintenance of neuroblast polarity. Predicted to be active in cytoplasm and microtubule cytoskeleton. Is expressed in adult head; embryonic/larval gut; and larval brain. Orthologous to human ARL2 (ADP ribosylation factor like GTPase 2). [provided by Alliance of Genome Resources, Dec 2024]
    Orthologs
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    Genomic context

    See Arl2 in Genome Data Viewer
    Location:
    84F13-84F13; 3-48 cM
    Exon count:
    3
    Annotation release Status Assembly Chr Location
    Release 6.54 current Release 6 plus ISO1 MT (GCF_000001215.4) 3R NT_033777.3 (8341100..8341872)
    Release 5.57 previous assembly Release 5 (GCF_000001215.2) 3R NT_033777.2 (4166822..4167594)

    Chromosome 3R - NT_033777.3Genomic Context describing neighboring genes Neighboring gene Pox meso Neighboring gene uncharacterized protein Neighboring gene Cytochrome c oxidase subunit 7A Neighboring gene Polynucleotide kinase 3'-phosphatase Neighboring gene Cytochrome c oxidase subunit 7A-like Neighboring gene Dipeptidyl aminopeptidase III

    Genomic regions, transcripts, and products

    Pathways from PubChem

    Interactions

    General gene information

    Gene Ontology Provided by FlyBase

    Function Evidence Code Pubs
    enables GTP binding  
    enables GTP binding  
    enables GTP binding PubMed 
    enables GTP binding PubMed 
    enables GTPase activity  
    enables GTPase activity  
    Component Evidence Code Pubs
    is_active_in cytoplasm  
    is_active_in microtubule cytoskeleton  
    located_in mitochondrial intermembrane space  

    General protein information

    Preferred Names
    ADP ribosylation factor-like 2
    Names
    ADP ribosylation factor 84F
    ADP ribosylation factor like-2
    Arl2-PA
    CG7435-PA
    arflike-2

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NT_033777.3 Reference assembly

      Range
      8341100..8341872
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_057538.3 → NP_476886.1  ADP ribosylation factor-like 2 [Drosophila melanogaster]

      See identical proteins and their annotated locations for NP_476886.1

      Status: REVIEWED

      UniProtKB/Swiss-Prot
      B5RJE0, Q06849, Q95TW2, Q9VHS1
      Related
      FBpp0081328
      Conserved Domains (1) summary
      cd04154
      Location:3 → 175
      Arl2; Arf-like 2 (Arl2) GTPase
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