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    Ssrp Structure specific recognition protein [ Drosophila melanogaster (fruit fly) ]

    Gene ID: 37767, updated on 17-Dec-2024

    Summary

    Official Symbol
    Ssrpprovided by FlyBase
    Official Full Name
    Structure specific recognition proteinprovided by FlyBase
    Primary source
    FLYBASE:FBgn0010278
    Locus tag
    Dmel_CG4817
    See related
    AllianceGenome:FB:FBgn0010278
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Drosophila melanogaster
    Lineage
    Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota; Neoptera; Endopterygota; Diptera; Brachycera; Muscomorpha; Ephydroidea; Drosophilidae; Drosophila; Sophophora
    Also known as
    Cf5; CG4817; Dmel\CG4817; dSsrp; dSSRP; DssRP; dSSRP1; ssrp; SSRP; SSRP1
    Summary
    Enables chromo shadow domain binding activity; nucleosomal DNA binding activity; and protein heterodimerization activity. Involved in several processes, including follicle cell of egg chamber development; negative regulation of protein phosphorylation; and positive regulation of actin filament polymerization. Located in cytosol and nucleolus. Part of FACT complex. Colocalizes with polytene chromosome interband and polytene chromosome puff. Is expressed in several structures, including adult head; central brain primordium; ganglia; gut section; and nurse cell. Orthologous to human SSRP1 (structure specific recognition protein 1). [provided by Alliance of Genome Resources, Dec 2024]
    Orthologs
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    Genomic context

    See Ssrp in Genome Data Viewer
    Location:
    60A2-60A2; 2-105 cM
    Exon count:
    3
    Annotation release Status Assembly Chr Location
    Release 6.54 current Release 6 plus ISO1 MT (GCF_000001215.4) 2R NT_033778.4 (23806361..23809004, complement)
    Release 5.57 previous assembly Release 5 (GCF_000001215.2) 2R NT_033778.3 (19693884..19696527, complement)

    Chromosome 2R - NT_033778.4Genomic Context describing neighboring genes Neighboring gene uncharacterized protein Neighboring gene uncharacterized protein Neighboring gene uncharacterized protein Neighboring gene uncharacterized protein Neighboring gene antisense RNA:CR44807 Neighboring gene NTF2-related export protein 1 Neighboring gene pippin

    Genomic regions, transcripts, and products

    Bibliography

    GeneRIFs: Gene References Into Functions

    What's a GeneRIF?

    Pathways from PubChem

    Interactions

    General gene information

    Gene Ontology Provided by FlyBase

    Function Evidence Code Pubs
    enables DNA binding  
    enables chromo shadow domain binding PubMed 
    enables histone binding  
    enables nucleosomal DNA binding PubMed 
    enables nucleosome binding  
    enables nucleosome binding PubMed 
    enables protein binding PubMed 
    enables protein heterodimerization activity PubMed 
    Component Evidence Code Pubs
    part_of FACT complex  
    part_of FACT complex PubMed 
    located_in cytosol PubMed 
    located_in nucleolus PubMed 
    located_in nucleus PubMed 
    located_in nucleus  
    colocalizes_with polytene chromosome interband PubMed 
    colocalizes_with polytene chromosome puff PubMed 

    General protein information

    Preferred Names
    structure specific recognition protein
    Names
    CG4817-PA
    Ssrp-PA
    chorion factor
    structure-specific recognition protein

    NCBI Reference Sequences (RefSeq)

    NEW Try the new Transcript table

    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NT_033778.4 Reference assembly

      Range
      23806361..23809004 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_079106.3 → NP_523830.2  structure specific recognition protein [Drosophila melanogaster]

      See identical proteins and their annotated locations for NP_523830.2

      Status: REVIEWED

      UniProtKB/Swiss-Prot
      Q05344, Q86NM5, Q9W1J4
      UniProtKB/TrEMBL
      B5RJ65
      Related
      FBpp0072151
      Conserved Domains (4) summary
      COG5165
      Location:20 → 499
      POB3; Nucleosome-binding factor SPN, POB3 subunit [Transcription / DNA replication, recombination, and repair / Chromatin structure and dynamics]
      cd13231
      Location:332 → 427
      PH2_SSRP1-like; Structure Specific Recognition protein 1 (SSRP1) Pleckstrin homology (PH) domain, repeat 2
      pfam00505
      Location:557 → 620
      HMG_box; HMG (high mobility group) box
      pfam03531
      Location:75 → 284
      SSrecog; Structure-specific recognition protein (SSRP1)
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