GEO DataSets

(Submitter supplied) Reports show that miRNAs have been implicated in various cancers and functions as both oncogenes and tumor suppressors in tumour initiation, progression, and response to treatment. Our study is conducted to identify circulating miRNA profile in NPC patients using whole blood samples with clinical significant diagnostic value. Microarray profiling identified 117 differentially expressed miRNAs (fold change≥1.5) between NPC patients and healthy control and 164 differentially expressed miRNAs (fold change≥1.5) between NPC and HNT patients and healthy control. more...

Organism:

Homo sapiens

Type:

Non-coding RNA profiling by array

Platform:

GPL19888

180 Samples

Download data: GPR

(Submitter supplied) Nasopharyngeal carcinoma (NPC) is a challenging cancer that is rare in the United States but shows exceptionally high incidence in Southern China, Indonesia, and Malaysia. While the hallmark of NPC is striking geographic variation, early detection and clinical management are also critical characteristics of this cancer. The etiology of NPC is complex, involving the interplay of multiple factors, including Epstein Barr Virus (EBV), which appears to play an oncogenic role. more...

Organism:

Homo sapiens

Type:

Non-coding RNA profiling by array

Platform:

GPL16770

8 Samples

Download data: TXT

(Submitter supplied) Nasopharyngeal carcinoma is a squamous cell carcinoma arising from the nasopharynx epithelium. So far, there have been no effective biomarkers to predict the radiosensitivity of NPC. Based on miRNA profile screened out from NPC patients with different radiosensitivity, this study was conducted to explore the correlation between serum miRNAs and radiotherapy response in NPC, and to identify biomarkers for predicting the radiosensitivity of NPC.

Organism:

Homo sapiens

Type:

Non-coding RNA profiling by array

Platform:

GPL25134

12 Samples

Download data: TXT

(Submitter supplied) We performed miRNA microarray analysis to find differentially expressed miRNAs between nasopharyngeal carcinoma patients and normal control subjects

Organism:

synthetic construct; Homo sapiens

Type:

Non-coding RNA profiling by array

Platform:

GPL17107

30 Samples

Download data: GPR, TXT

(Submitter supplied) As the biogenesis of miRNAs depends on the cleavage by the RNase III enzyme Dicer, miR-18a may change the miRNA expression profiles by targeting dicer. We then performed the miRNA array assay to investigate the miRNA profiles change caused by miR-18a.

Organism:

Homo sapiens

Type:

Non-coding RNA profiling by array

Platform:

GPL8179

3 Samples

Download data: TXT

(Submitter supplied) Gene expression patterns can be used as prognostic biomarkers in various types of cancer. We aimed to identify a gene expression pattern for individual distant metastatic risk assessment in patients with locoregionally advanced nasopharyngeal carcinoma (LA-NPC).

Organism:

Homo sapiens

Type:

Expression profiling by array

Platform:

GPL19251

48 Samples

Download data: CEL, CSV, XLSX

(Submitter supplied) Accumulating evidence indicates that human circulating microRNAs (miRNAs) could serve as diagnostic and prognostic biomarkers in various cancers. We aimed to explore novel miRNA biomarkers in the blood of breast cancer patients based on miRNA profiling. A miRCURY™ LNA Array was used to identify differentially altered miRNAs in the whole blood of breast cancer patients (n = 6) and healthy controls (n = 6). more...

Organism:

synthetic construct; Homo sapiens

Type:

Non-coding RNA profiling by array

Platform:

GPL22003

12 Samples

Download data: GPR, TXT

(Submitter supplied) Publication: Identification of a microRNA signature associated with risk of distant metastasis in nasopharyngeal carcinoma Purpose Despite significant improvement in locoregional control in the contemporary era of nasopharyngeal carcinoma (NPC) treatment, patients still suffer from a significant risk of distant metastasis (DM). Identifying those patients at risk of DM would aid in personalized treatment in the future. more...

Organism:

Homo sapiens

Type:

Non-coding RNA profiling by array

Platform:

GPL20699

263 Samples

Download data: RCC, TXT

(Submitter supplied) This SuperSeries is composed of the SubSeries listed below.

Organism:

Homo sapiens

Type:

Expression profiling by array; Non-coding RNA profiling by array

Platforms:

GPL15019 GPL570

10 Samples

Download data: CEL, TXT

(Submitter supplied) Most of the NPC patients suffer from local recurrences and distant metastases within 1.5 years after radiotherapy due to radioresistance. Distinct patterns of miRNa expression and signatures were found in NPC, and have been used to associate them with cell proliferation, apoptosis, invasion and metastasis, but few miRNA expression profiling studies have been focused on the tumor radioresistance.We used miRNA expression microarray analyses to identify the difference of miRNA in radioresistant NPC CNE2-IR cells and radiosensitive CNE2 cells.

Organism:

Homo sapiens

Type:

Non-coding RNA profiling by array

Platform:

GPL15019

6 Samples

Download data: TXT, XLS

(Submitter supplied) Most of the NPC patients suffer from local recurrences and distant metastases within 1.5 years after radiotherapy due to radioresistance. Distinct patterns of gene expression and signatures were found in NPC, and have been used to associate them with cell proliferation, apoptosis, invasion and metastasis, but few gene expression profiling studies have been focused on the tumor radioresistance.We used gene expression microarray analyses to identify the difference of mRNA in radioresistant NPC CNE2-IR cells and radiosensitive CNE2 cells.

Organism:

Homo sapiens

Type:

Expression profiling by array

Platform:

GPL570

4 Samples

Download data: CEL, XLS

(Submitter supplied) By using NGS-derived retinal transcriptome profiling (RNA-seq) to compare the gene expression profiling between 4 differently treated NPC cells

Organism:

Homo sapiens

Type:

Expression profiling by high throughput sequencing

Platform:

GPL11154

4 Samples

Download data: TXT

(Submitter supplied) Epstein-Barr virus (EBV) has been etiologically linked to human malignancies including Nasopharyngeal Carcinoma (NPC). Although EBV-encoded miRNAs have been shown to contribute to viral latency, host cell survival and immune evasion, their direct impact on cancer progression in their human host remains unclear. In the current study, based on a miRNA expression profiling analysis of a larger number of clinical specimens using a miRNA array platform containing human, EBV and other species miRNA probes., we found that some EBV-miR-BARTs were highly expressed in NPC. more...

Organism:

Rattus norvegicus; Macacine gammaherpesvirus 4; Human gammaherpesvirus 8; Betapolyomavirus macacae; Mus musculus; Homo sapiens

Type:

Non-coding RNA profiling by array

Platform:

GPL16414

40 Samples

Download data: GPR

(Submitter supplied) This SuperSeries is composed of the SubSeries listed below.

Organism:

Homo sapiens; Mus musculus; Human gammaherpesvirus 8; Betapolyomavirus macacae; Rattus norvegicus; Macacine gammaherpesvirus 4

Type:

Expression profiling by high throughput sequencing; Non-coding RNA profiling by array

Platforms:

GPL11154 GPL16414

44 Samples

Download data: GPR, TXT

(Submitter supplied) To identify serum miRNAs for the diagnosis of HCC, the profiling of 754 human miRNAs was analyzed in sera from six histopathologically confirmed HCC patients and eight CHB controls, using TaqMan Array Human MicroRNA A+B Cards Set v3.0 (Applied Biosystems, Foster City, CA). Serum miRNAs with differential levels between HCC and CHB were identified by comparing serum miRNA profiling of HCC patients with that of CHB controls.

Organism:

Homo sapiens

Type:

Other

Platform:

GPL16850

14 Samples

Download data: TXT

(Submitter supplied) Expression profiling of nasopharyngeal carcinoma patients comparing radio-sensitive samples with radio-resistant samples.

Organism:

Homo sapiens

Type:

Expression profiling by array

Platform:

GPL4381

20 Samples

Download data: TXT

(Submitter supplied) MiRNA profiling from whole blood (EDTA) was used to identify a miRNA profile applicable for early stage breast cancer detection

Organism:

Homo sapiens

Type:

Non-coding RNA profiling by array

Platform:

GPL14132

105 Samples

Download data: TXT

(Submitter supplied) microRNA profiling of hepatocellular carcinoma vs. matched noncancerous liver tissue

Organism:

Homo sapiens

Type:

Non-coding RNA profiling by array

Platform:

GPL14140

166 Samples

Download data: GPR

(Submitter supplied) Analysis of the levels of circulating miRNAs from women with early stage breast cancer and matched healthy controls.

Organism:

Homo sapiens

Type:

Non-coding RNA profiling by array

Platform:

GPL8179

40 Samples

Download data: TXT

(Submitter supplied) Peripheral whole blood transcriptome profiles of pregnant women with normal pregnancy and preeclampsia from 10-18 weeks of gestational age enrolled in the “Vitamin D Antenatal Asthma Reduction Trial” (VDAART).

Organism:

Homo sapiens

Type:

Expression profiling by array; Other

Platforms:

GPL6244 GPL19162

316 Samples

Download data: CEL, TXT