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Links from GEO DataSets

Items: 20

1.

Time- and phase-dependent expression profile of miRNA and mRNA in human microglial cells (CHME3) infected with Japanese encephalitis virus (JEV) P20778 strain

(Submitter supplied) This SuperSeries is composed of the SubSeries listed below.
Organism:
synthetic construct; Homo sapiens
Type:
Expression profiling by array; Non-coding RNA profiling by array
Platforms:
GPL15207 GPL16384
30 Samples
Download data: CEL
Series
Accession:
GSE57647
ID:
200057647
2.

MicroRNA expression profile in CHME3 cells infected with Japanese encephalitis virus

(Submitter supplied) CHME3 cells grown on six-wells were infected with Japanese encephalitis virus (JEV) (P20778 strain), and total RNA was isolated from cells at 6, 24 and 48 h of post infection. MicroRNA expression was significantly altered in JEV-infected human microglial cells. A time-dependent change in microRNA profile was noted. Bioinformatics analysis identified anti-correlation between differentially expressed miRNAs and the gene expression at different time point which ultimately affected several signalling pathways in microglia cells. more...
Organism:
Homo sapiens; synthetic construct
Type:
Non-coding RNA profiling by array
Platform:
GPL16384
18 Samples
Download data: CEL
Series
Accession:
GSE57410
ID:
200057410
3.

mRNA expression profile in CHME3 cells infected with Japanese encephalitis virus

(Submitter supplied) CHME3 cells grown on six-wells were infected with Japanese encephalitis virus (JEV) (P20778 strain ) and total RNA was isolated from cells at 6, 24 and 48 h of post infection mRNA expression was significantly altered in JEV infected human microglial cells. A time dependant change in microRNA profile was noted. Bioinformatics analysis identified anti correlation between differentially expressed miRNAs and the gene expression at different time point which ultimately affected several signalling pathways in microglia cells. more...
Organism:
Homo sapiens
Type:
Expression profiling by array
Platform:
GPL15207
12 Samples
Download data: CEL
Series
Accession:
GSE57330
ID:
200057330
4.

Short-chain fatty acids abrogate Japanese encephalitis virus-induced inflammation in microglial cells via miR200a-3p/ZBTB20/Ikβα axis

(Submitter supplied) Japanese encephalitis virus (JEV), a member of the Flaviviridae family, is a leading cause of viral encephalitis in humans. Survivors of this infection often develop life-long neurological sequelae. Short-chain fatty acids (SCFAs) produced in the gut are vital mediators of the gut-brain axis. We aimed to study microRNA-based mechanisms of SCFAs in an in vitro model of JEV infection. N9 microglial cells were pre-treated with SCFA cocktail before JEV infection. more...
Organism:
Mus musculus
Type:
Non-coding RNA profiling by high throughput sequencing
Platform:
GPL15103
24 Samples
Download data: XLSX
Series
Accession:
GSE267173
ID:
200267173
5.

Dynamic miRNA-mRNA regulations are essential for maintaining Drosophila immune homeostasis during Micrococcus luteus infection

(Submitter supplied) Pathogen bacteria infections can lead to dynamic changes of microRNA (miRNA) and mRNA expression profiles, which may control synergistically the outcome of immune responses. To reveal the role of dynamic miRNA-mRNA regulation in Drosophila innate immune responses, we have detailedly analyzed the paired miRNA and mRNA expression profiles at three time points during Drosophila adult males with Micrococcus luteus (M. more...
Organism:
Drosophila melanogaster
Type:
Expression profiling by high throughput sequencing
Platform:
GPL13304
18 Samples
Download data: XLSX
Series
Accession:
GSE173733
ID:
200173733
6.

miRNA expression profiles and molecular networks in resting and LPS-activated BV-2 microglia - Effect of cannabinoids

(Submitter supplied) Cannabinoids are known to exert immunosuppressive activities. However, the mechanisms which contribute to these effects are unknown. Using lipopolysaccharide (LPS) to activate BV-2 microglial cells, we examined how Δ9-tetrahydrocannabinol (THC), the major psychoactive component of marijuana, and cannabidiol (CBD) the non-psychoactive component, modulate the inflammatory response through miRNA expression
Organism:
Mus musculus
Type:
Non-coding RNA profiling by high throughput sequencing
Platform:
GPL17021
18 Samples
Download data: TXT
Series
Accession:
GSE123262
ID:
200123262
7.

microRNA expression profiles of distinct human and mouse mammary epithelial cell types

(Submitter supplied) This SuperSeries is composed of the SubSeries listed below.
Organism:
Homo sapiens; Mus musculus; Rattus norvegicus
Type:
Expression profiling by RT-PCR
Platforms:
GPL10331 GPL18234
32 Samples
Download data
Series
Accession:
GSE67056
ID:
200067056
8.

microRNA expression profiles of distinct mouse mammary epithelial cell types

(Submitter supplied) RNA samples were prepared from freshly sorted mammary cell subpopulations (MaSC/basal-enriched, luminal progenitor, mature luminal and stromal) from five sets of adult mice. High throughput RT-PCR was used to measure the global microRNA expression profiles of each cell subpopulation. The expression profiles were compared between cell subpopulations to gain insight into the regulation of lineage-restricted genes.
Organism:
Rattus norvegicus; Mus musculus
Type:
Expression profiling by RT-PCR
Platform:
GPL10331
14 Samples
Download data: XLS
Series
Accession:
GSE67055
ID:
200067055
9.

microRNA expression profiles of distinct human mammary epithelial cell types

(Submitter supplied) RNA samples were prepared from freshly sorted mammary cell subpopulations (MaSC/basal-enriched, luminal progenitor, mature luminal and stromal) from five human donors. High throughput RT-PCR was used to measure the global microRNA expression profiles of each cell subpopulation. The expression profiles were compared between cell subpopulations to gain insight into the regulation of lineage-restricted genes.
Organism:
Homo sapiens
Type:
Expression profiling by RT-PCR
Platform:
GPL18234
18 Samples
Download data: XLS
Series
Accession:
GSE67054
ID:
200067054
10.

Mucosal expression profiling in (un)inflamed colon of patients with ulcerative colitis (UC)

(Submitter supplied) This SuperSeries is composed of the SubSeries listed below.
Organism:
Homo sapiens; synthetic construct
Type:
Expression profiling by array; Non-coding RNA profiling by array
Platforms:
GPL14613 GPL6244
48 Samples
Download data: CEL
Series
Accession:
GSE48959
ID:
200048959
11.

Mucosal gene expression profiling in (un)inflamed colon of patients with ulcerative colitis (UC)

(Submitter supplied) In this study, we investigated if miRNA expression in UC mucosa is altered and correlated our findings with mucosal mRNA expression. Integration of mRNA and miRNA expression profiling may allow the identification of functional links between dysregulated miRNAs and their predicted target mRNA.
Organism:
Homo sapiens
Type:
Expression profiling by array
Platform:
GPL6244
21 Samples
Download data: CEL
Series
Accession:
GSE48958
ID:
200048958
12.

Mucosal miRNA expression profiling in (un)inflamed colon of patients with ulcerative colitis (UC)

(Submitter supplied) In this study, we investigated if miRNA expression in UC mucosa is altered and correlated our findings with mucosal mRNA expression. Integration of mRNA and miRNA expression profiling may allow the identification of functional links between dysregulated miRNAs and their predicted target mRNA.
Organism:
synthetic construct; Homo sapiens
Type:
Non-coding RNA profiling by array
Platform:
GPL14613
27 Samples
Download data: CEL
Series
Accession:
GSE48957
ID:
200048957
13.

Integrated expression profiles of mRNA and miRNA in polarized primary murine microglia

(Submitter supplied) This SuperSeries is composed of the SubSeries listed below.
Organism:
Mus musculus; synthetic construct
Type:
Expression profiling by array; Non-coding RNA profiling by array
Platforms:
GPL14613 GPL11078
18 Samples
Download data: CEL
Series
Accession:
GSE49331
ID:
200049331
14.

Integrated expression profiles of mRNA and miRNA in polarized primary murine microglia (miRNA)

(Submitter supplied) The aim of this study was to determine the role that miRNAs have on influencing murine microgial phenotypes under M1(LPS) and M2a (IL-4) stimulating conditions. This Series includes expression data obtained from miRNA gene expression microarrays; mRNA expression profiles obtained from the same RNA samples were deposited as a separate Series.
Organism:
synthetic construct; Mus musculus
Type:
Non-coding RNA profiling by array
Platform:
GPL14613
9 Samples
Download data: CEL
Series
Accession:
GSE49330
ID:
200049330
15.

Integrated expression profiles of mRNA and miRNA in polarized primary murine microglia (mRNA)

(Submitter supplied) The aim of this study was to determine the role that miRNAs have on influencing murine microgial phenotypes under M1(LPS) and M2a (IL-4) stimulating conditions. This Series includes expression data obtained from mRNA gene expression microarrays; miRNA expression profiles obtained from the same RNA samples were deposited as a separate Series.
Organism:
Mus musculus
Type:
Expression profiling by array
Platform:
GPL11078
9 Samples
Download data: CEL
Series
Accession:
GSE49329
ID:
200049329
16.

Comparative Expression Profile of miRNA and mRNA in Primary Peripheral Blood Mononuclear Cells Infected with Human Immunodeficiency Virus (HIV-1)

(Submitter supplied) This SuperSeries is composed of the SubSeries listed below.
Organism:
Homo sapiens
Type:
Expression profiling by array; Non-coding RNA profiling by array
Platforms:
GPL6947 GPL14907
24 Samples
Download data
Series
Accession:
GSE33879
ID:
200033879
17.

Comparative Expression Profile of miRNA and mRNA in Primary Peripheral Blood Mononuclear Cells Infected with Human Immunodeficiency Virus (HIV-1) [mRNA]

(Submitter supplied) Host cells respond to exogenous infectious agents such as viruses, including HIV-1. Studies have evaluated the changes associated with virus infection at the transcriptional and translational levels of the cellular genes involved in specific pathways. While this approach is useful, in our view it provides only a partial view of genome-wide changes. Recently, technological advances in the expression profiling at the microRNA (miRNA) and mRNA levels have made it possible to evaluate the changes in the components of multiple pathways. more...
Organism:
Homo sapiens
Type:
Expression profiling by array
Platform:
GPL6947
12 Samples
Download data: TXT
Series
Accession:
GSE33877
ID:
200033877
18.

Comparative Expression Profile of miRNA and mRNA in Primary Peripheral Blood Mononuclear Cells Infected with Human Immunodeficiency Virus (HIV-1) [miRNA]

(Submitter supplied) Host cells respond to exogenous infectious agents such as viruses, including HIV-1. Studies have evaluated the changes associated with virus infection at the transcriptional and translational levels of the cellular genes involved in specific pathways. While this approach is useful, in our view it provides only a partial view of genome-wide changes. Recently, technological advances in the expression profiling at the microRNA (miRNA) and mRNA levels have made it possible to evaluate the changes in the components of multiple pathways. more...
Organism:
Homo sapiens
Type:
Non-coding RNA profiling by array
Platform:
GPL14907
12 Samples
Download data: XLS
Series
Accession:
GSE33837
ID:
200033837
19.

Host-influenza A virus(infA) interactions

(Submitter supplied) This SuperSeries is composed of the SubSeries listed below.
Organism:
Homo sapiens
Type:
Non-coding RNA profiling by array; Expression profiling by array
Platforms:
GPL15271 GPL6947
133 Samples
Download data
Series
Accession:
GSE36555
ID:
200036555
20.

mRNA profiling during infection with H1N1 influenza A virus (A/Mexico/InDRE4487/H1N1/2009)

(Submitter supplied) MicroRNAs (miRNAs) repress the expression levels of genes by binding to mRNA transcripts, acting as master regulators of cellular processes. Differential expression of miRNAs has been linked to viral-associated diseases involving members of the hepacivirus, herpesvirus, and retrovirus families. In contrast, limited biological and molecular information has been reported on the potential role of cellular miRNAs in the lifecycle of influenza A viruses (infA). more...
Organism:
Homo sapiens
Type:
Expression profiling by array
Platform:
GPL6947
40 Samples
Download data: TXT
Series
Accession:
GSE36553
ID:
200036553
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