Similar studies for GEO DataSets (Select 200056949) - GEO DataSets

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Items: 20

Select item 2000569491.

Regulatory consequences of TARBP2 knock-down in Dicer-null MEFs

(Submitter supplied) siRNA-mediated knock-down followed by transcriptomic profiling revealed that silencing of TARBP2 resulted in a significant up-regulation of sRSE-carrying transcripts.

Organism:: Mus musculus

Type:: Expression profiling by array

Platform:: GPL6885
5 Samples

Download data: TXT

Series

Accession:: GSE56949

ID:: 200056949

PubMed Full text in PMC Similar studies Analyze with GEO2R

Select item 2000569502.

Regulatory consequences of TARBP2 knock-down in MDA-LM2-shDicer cell-line

(Submitter supplied) siRNA-mediated knock-down followed by transcriptomic profiling revealed that silencing of TARBP2 resulted in a significant up-regulation of sRSE-carrying transcripts.

Organism:: Homo sapiens

Type:: Expression profiling by array

Platform:: GPL10558
4 Samples

Download data: TXT

Series

Accession:: GSE56950

ID:: 200056950

PubMed Full text in PMC Similar studies Analyze with GEO2R

Select item 2000569483.

Regulatory consequences of TARBP2 over-expression in MDA-231 cell-line

(Submitter supplied) Transient transfection of TARBP2 expression vectors (along with GFP controls) followed by transcriptomic profiling revealed that over-expression of TARBP2 resulted in a significant enrichment of sRSE-carrying transcripts among the down-regulated transcripts.

Organism:: Homo sapiens

Type:: Expression profiling by array

Platform:: GPL10558
4 Samples

Download data: TXT

Series

Accession:: GSE56948

ID:: 200056948

PubMed Full text in PMC Similar studies Analyze with GEO2R

Select item 2000569474.

Regulatory consequences of TARBP2 knock-down in CN-LM1a cell-line

(Submitter supplied) siRNA-mediated knock-down followed by transcriptomic profiling revealed that silencing of TARBP2 resulted in a significant up-regulation of sRSE-carrying transcripts.

Organism:: Homo sapiens

Type:: Expression profiling by array

Platform:: GPL10558
4 Samples

Download data: TXT

Series

Accession:: GSE56947

ID:: 200056947

PubMed Full text in PMC Similar studies Analyze with GEO2R

Select item 2000569455.

Regulatory consequences of TARBP2 knock-down in293T cell-line

(Submitter supplied) siRNA-mediated knock-down followed by transcriptomic profiling revealed that silencing of TARBP2 resulted in a significant up-regulation of sRSE-carrying transcripts.

Organism:: Homo sapiens

Type:: Expression profiling by array

Platform:: GPL10558
3 Samples

Download data: TXT

Series

Accession:: GSE56945

ID:: 200056945

PubMed Full text in PMC Similar studies Analyze with GEO2R

Select item 2000496496.

Metastasis-suppressor transcript destabilization through TARBP2 binding of mRNA hairpins

(Submitter supplied) This SuperSeries is composed of the SubSeries listed below.

Organism:: Homo sapiens; Mus musculus

Type:: Expression profiling by high throughput sequencing; Expression profiling by array

Platforms:: GPL10558 GPL6885 GPL11154
78 Samples

Download data

Series

Accession:: GSE49649

ID:: 200049649

PubMed Full text in PMC Similar studies Analyze with GEO2R

Select item 2000496487.

TARBP2 HITS-CLIP

(Submitter supplied) In order to identify TARBP2 binding sites on endogenous RNA, we performed HITS-CLIP on a myc-tagged TARBP2 expressing cell-line (transient transfection)

Organism:: Homo sapiens

Type:: Expression profiling by high throughput sequencing

Platform:: GPL11154
2 Samples

Download data: BED

Series

Accession:: GSE49648

ID:: 200049648

PubMed Full text in PMC Similar studies SRA Run Selector

Select item 2000496138.

Regulatory consequences of ZNF395 knock-down in MDA-LM2-shTARBP2 cell-line

(Submitter supplied) shRNA-mediated knock-down followed by transcriptomic profiling revealed that silencing of ZNF395 resulted in a significant up-regulation in several key oncogenes.

Organism:: Homo sapiens

Type:: Expression profiling by array

Platform:: GPL10558
8 Samples

Download data: TXT

Series

Accession:: GSE49613

ID:: 200049613

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Select item 2000496129.

Regulatory consequences of TARBP2 knock-down in MDA-LM2 cell-line [stability experiment]

(Submitter supplied) siRNA-mediated knock-down followed by transcriptomic profiling revealed that silencing of TARBP2 resulted in a significant increase in the stability of sRSE-carrying transcripts.

Organism:: Homo sapiens

Type:: Expression profiling by array

Platform:: GPL10558
8 Samples

Download data: TXT

Series

Accession:: GSE49612

ID:: 200049612

PubMed Full text in PMC Similar studies Analyze with GEO2R

Select item 20004961110.

Regulatory consequences of TARBP2 knock-down in MDA-LM2 cell-line

(Submitter supplied) siRNA-mediated knock-down followed by transcriptomic profiling revealed that silencing of TARBP2 resulted in a significant up-regulation of sRSE-carrying transcripts.

Organism:: Homo sapiens

Type:: Expression profiling by array

Platform:: GPL10558
4 Samples

Download data: TXT

Series

Accession:: GSE49611

ID:: 200049611

PubMed Full text in PMC Similar studies Analyze with GEO2R

Select item 20004960911.

In-culture titration experiment for sRSE

(Submitter supplied) In order to test the transcriptome-wide functionality of the identified sRSE instances, we performed an in vivo titration experiment in which synthetic RNA oligonucleotides harboring tandem sRSE1 repeats were used as intracellular decoys that would bind the putative trans factor, preventing it from targeting endogenous transcripts.

Organism:: Homo sapiens

Type:: Expression profiling by array

Platform:: GPL10558
4 Samples

Download data: TXT

Series

Accession:: GSE49609

ID:: 200049609

PubMed Full text in PMC Similar studies Analyze with GEO2R

Select item 20004960812.

Differential transcript stability measurements in MDA-MB-231 vs. MDA-LM2 cells

(Submitter supplied) We performed whole-genome stability measurements for MDA-MB-231 and its highly metastatic derivative MDA-LM2. Our goal was to identify post-transcriptonal regulons that are deregulated en route to higher metastatic capacity.

Organism:: Homo sapiens

Type:: Expression profiling by high throughput sequencing

Platform:: GPL11154
32 Samples

Download data: TXT

Series

Accession:: GSE49608

ID:: 200049608

PubMed Full text in PMC Similar studies Analyze with GEO2R SRA Run Selector

Select item 20007648813.

Muscleblind-like 1 suppresses breast cancer metastatic colonization and stabilizes metastasis suppressor transcripts

(Submitter supplied) This SuperSeries is composed of the SubSeries listed below.

Organism:: Homo sapiens

Type:: Expression profiling by array; Expression profiling by high throughput sequencing; Other

Platforms:: GPL11154 GPL10558
16 Samples

Download data

Series

Accession:: GSE76488

ID:: 200076488

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Select item 20007648714.

MBNL1-dependent modulation of gene expression in MDA-MB-231 breast cancer cells

(Submitter supplied) To identify MBNL1-dependent changes in gene expression, MDA-MB-231 cells expressing either control or MBNL1-targeting shRNAs were transcriptomically profiled.

Organism:: Homo sapiens

Type:: Expression profiling by high throughput sequencing

Platform:: GPL11154
6 Samples

Download data: TXT

Series

Accession:: GSE76487

ID:: 200076487

PubMed Full text in PMC Similar studies Analyze with GEO2R SRA Run Selector

Select item 20007648615.

MBNL1 HITS-CLIP in MDA-MB-231 breast cancer cells

(Submitter supplied) HITS-CLIP was performed to identify endogenous MBNL1 binding sites on RNAs in MDA-MB-231 breast cancer cells.

Organism:: Homo sapiens

Type:: Other

Platform:: GPL11154
2 Samples

Download data: BED

Series

Accession:: GSE76486

ID:: 200076486

PubMed Full text in PMC Similar studies Analyze with GEO2R SRA Run Selector

Select item 20007648516.

MBNL1-dependent modulation of transcript stability

(Submitter supplied) In order to identify MBNL1-dependent changes in MBNL1 target transcript stability, MBNL1 levels in MDA-MB-231 breast cancer cells were stably knocked-down using short-hairpin RNAs. The cells were then treated with alpha-amanitin to inhibit transcription, RNA was isolated at 0 and 9 hours post-alpha-amanitin treatment, and the samples were transcriptomically profiled.

Organism:: Homo sapiens

Type:: Expression profiling by array

Platform:: GPL10558
8 Samples

Download data: TXT

Series

Accession:: GSE76485

ID:: 200076485

PubMed Full text in PMC Similar studies Analyze with GEO2R

Select item 20013174517.

SRSF1 HITS-CLIP in MDA-LM2

(Submitter supplied) To identify SRSF1 binding sites on RNAs, we performed HITS-CLIP of endogenous SRSF1 in MDA-LM2 cells

Organism:: Homo sapiens

Type:: Expression profiling by high throughput sequencing

Platform:: GPL16791
2 Samples

Download data: BED

Series

Accession:: GSE131745

ID:: 200131745

PubMed Full text in PMC Similar studies Analyze with GEO2R SRA Run Selector

Select item 20013089418.

siRNA-mediated knockdown

(Submitter supplied) This SuperSeries is composed of the SubSeries listed below.

Organism:: Homo sapiens

Type:: Expression profiling by high throughput sequencing

Platforms:: GPL20301 GPL18573 GPL16791
40 Samples

Download data: FPKM_TRACKING, TXT

Series

Accession:: GSE130894

ID:: 200130894

PubMed Full text in PMC Similar studies

Select item 20013089319.

MeRIP-seq of control and TARBP2 knockdown cells

(Submitter supplied) To identify changes in methylation patterns following TARBP2 knockdown, m6A-IP followed by RNA-seq was performed on breast cancer cells expressing shRNAs against TARBP2 (and non-targeting shControl cells).

Organism:: Homo sapiens

Type:: Expression profiling by high throughput sequencing

Platform:: GPL16791
8 Samples

Download data: BED, TXT

Series

Accession:: GSE130893

ID:: 200130893

PubMed Full text in PMC Similar studies Analyze with GEO2R SRA Run Selector

Select item 20013087320.

Total RNA-seq of siRNA-mediated WTAP and TPR knockdown

(Submitter supplied) To identify changes in splicing patterns following WTAP and TPR knockdown, RNA-sequencing was performed on breast cancer cells transfected with siRNAs targeting WTAP or TPR.