|
| Status |
Public on Jul 24, 2014 |
| Title |
Regulatory consequences of TARBP2 knock-down in Dicer-null MEFs |
| Organism |
Mus musculus |
| Experiment type |
Expression profiling by array
|
| Summary |
siRNA-mediated knock-down followed by transcriptomic profiling revealed that silencing of TARBP2 resulted in a significant up-regulation of sRSE-carrying transcripts.
|
| |
|
| Overall design |
Two independent siRNAs were used to knock down TARBP2 in metastatic Dicer-null cells. The cells were then subjected to transcripome profiling in comparison to mock-transfected cells.
|
| |
|
| Contributor(s) |
Goodarzi H, Zhang S, Buss CG, Fish L, Tavazoie S, Tavazoie SF |
| Citation(s) |
25043050 |
| |
| Submission date |
Apr 21, 2014 |
| Last update date |
Jun 14, 2018 |
| Contact name |
Hani Goodarzi |
| Organization name |
UCSF
|
| Department |
Biochemistry and Biophysics
|
| Street address |
600 16th St, GH S312D
|
| City |
San Francisco |
| State/province |
CA |
| ZIP/Postal code |
94158 |
| Country |
USA |
| |
|
| Platforms (1) |
| GPL6885 |
Illumina MouseRef-8 v2.0 expression beadchip |
|
| Samples (5)
|
| GSM1372083 |
TARBP2 knock-down (siTARBP2-1)_DICER-null MEF |
| GSM1372084 |
TARBP2 knock-down (siTARBP2-2)_DICER-null MEF |
| GSM1372085 |
Control (siControl-1)_DICER-null MEF |
|
| This SubSeries is part of SuperSeries: |
| GSE49649 |
Metastasis-suppressor transcript destabilization through TARBP2 binding of mRNA hairpins |
|
| Relations |
| BioProject |
PRJNA245040 |
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