GEO DataSets

Analysis of follicular dendritic cell (FDCs) enriched splenocytes. FDCs are important in the formation of lymphoid germinal centers (GCs), where rapid B-cell proliferation and differentiation occur. Results identify transcripts that are overrepresented in cells associated with FDC networks in GCs.

Organism:

Mus musculus

Type:

Expression profiling by array, count, 2 cell type sets

Platform:

GPL81

Series:

GSE2123

5 Samples

Download data: CEL

(Submitter supplied) treatment of mesenteric lymph nodes with soluble lymphotoxin-beta receptor for 0,1,2,3,27 and 35 days Keywords: time-course

Organism:

Mus musculus

Type:

Expression profiling by array

Datasets:

GDS2004 GDS2005

Platforms:

GPL340 GPL339

36 Samples

Download data: CEL

(Submitter supplied) Comparison of follicular dendritic cell-enriched versus -depleted splenocytes Keywords: parallel sample

Organism:

Mus musculus

Type:

Expression profiling by array

Datasets:

GDS1585 GDS1599 GDS1600

Platforms:

GPL81 GPL82 GPL83

14 Samples

Download data: CEL

Analysis of lymph nodes from animals treated with soluble lymphotoxin-beta receptor (LTbetaR)-immunoglobulin fusion protein (LTbetaR-Ig) for up to 35 days. LTbetaR-Ig inhibits LTbetaR activation, important in the differentiation of lymphoid germinal centers and follicular dendritic cells.

Organism:

Mus musculus

Type:

Expression profiling by array, count, 2 agent, 6 time sets

Platform:

GPL340

Series:

GSE2124

18 Samples

Download data: CEL

Analysis of lymph nodes from animals treated with soluble lymphotoxin-beta receptor (LTbetaR)-immunoglobulin fusion protein (LTbetaR-Ig) for up to 35 days. LTbetaR-Ig inhibits LTbetaR activation, important in the differentiation of lymphoid germinal centers and follicular dendritic cells.

Organism:

Mus musculus

Type:

Expression profiling by array, count, 2 agent, 6 time sets

Platform:

GPL339

Series:

GSE2124

18 Samples

Download data: CEL

Analysis of follicular dendritic cell (FDCs) enriched splenocytes. FDCs are important in the formation of lymphoid germinal centers (GCs), where rapid B-cell proliferation and differentiation occur. Results identify transcripts that are overrepresented in cells associated with FDC networks in GCs.

Organism:

Mus musculus

Type:

Expression profiling by array, count, 2 cell type sets

Platform:

GPL83

Series:

GSE2123

5 Samples

Download data: CEL

Analysis of follicular dendritic cell (FDCs) enriched splenocytes. FDCs are important in the formation of lymphoid germinal centers (GCs), where rapid B-cell proliferation and differentiation occur. Results identify transcripts that are overrepresented in cells associated with FDC networks in GCs.

Organism:

Mus musculus

Type:

Expression profiling by array, count, 2 cell type sets

Platform:

GPL82

Series:

GSE2123

4 Samples

Download data: CEL

(Submitter supplied) expression profiles of FDC and BMDC are compared Keywords: cell type comparison

Organism:

Mus musculus

Type:

Expression profiling by array

Platform:

GPL1261

6 Samples

Download data

(Submitter supplied) This SuperSeries is composed of the SubSeries listed below.

Organism:

Mus musculus; synthetic construct

Type:

Non-coding RNA profiling by array

Platforms:

GPL18398 GPL14613

16 Samples

Download data: CEL, TXT

(Submitter supplied) Follicular dendritic cells (FDC) are important stromal cells within the B cell follicles and germinal centres (GC) of secondary lymphoid tissues. FDC trap and retain native antigens on their surfaces in the form of immune complexes which they display to B cells, in order to select those cells with the highest antigen affinity. MicroRNAs are short, non-coding RNAs of approximately 18-25 nucleotides in length that regulate gene expression at the post-transcriptional level by repressing the translation of target genes. more...

Organism:

Mus musculus

Type:

Non-coding RNA profiling by array

Platform:

GPL18398

8 Samples

Download data: TXT

(Submitter supplied) Follicular dendritic cells (FDC) are important stromal cells within the B cell follicles and germinal centres (GC) of secondary lymphoid tissues. FDC trap and retain native antigens on their surfaces in the form of immune complexes which they display to B cells, in order to select those cells with the highest antigen affinity. MicroRNAs are short, non-coding RNAs of approximately 18-25 nucleotides in length that regulate gene expression at the post-transcriptional level by repressing the translation of target genes. more...

Organism:

Mus musculus; synthetic construct

Type:

Non-coding RNA profiling by array

Platform:

GPL14613

8 Samples

Download data: CEL

(Submitter supplied) In human chronic lymphocytic leukemia (CLL) pathogenesis B cell antigen receptor signaling seems important for leukemia B cell ontogeny, whereas the microenvironment influences B cell activation, tumor cell lodging and provision of antigenic stimuli. Using the murine Eμ-Tcl1 CLL model, we demonstrate that CXCR5-controlled access to follicular dendritic cells (FDCs) confers proliferative stimuli to leukemia B cells. more...

Organism:

Mus musculus

Type:

Expression profiling by array

Platform:

GPL19138

18 Samples

Download data: CEL

(Submitter supplied) Comparison between gene expression profiles of splenic stroma from wild type and lymphotoxin beta receptor knockout mice. The goal was to identify a set of genes which expression in splenic stroma is under lymphotoxin control and which can potentially be important for proper stroma development and function in secondary lymphoid organs.

Organism:

Mus musculus

Type:

Expression profiling by array

Platform:

GPL6103

8 Samples

Download data: IDAT, JPG, SDF, TIFF, TXT, XML

(Submitter supplied) This SuperSeries is composed of the SubSeries listed below.

Organism:

Homo sapiens; Mus musculus

Type:

Expression profiling by array

Platforms:

GPL570 GPL1261

16 Samples

Download data: CEL

(Submitter supplied) Microarrays of gene expression in human germinal center light zone and dark zone B cells sorted according to the expression of cell surface molecules CD83 and CXCR4 We used microarray data to identify genes differentially expressed by B cells in the light and dark zones of germinal centers from human tonsil specimens.

Organism:

Homo sapiens

Type:

Expression profiling by array

Platform:

GPL570

8 Samples

Download data: CEL

(Submitter supplied) Microarrays of gene expression in mouse germinal center light zone and dark zone B cells sorted according to the expression of cell surface molecules CD83 and CXCR4 We used microarray data to identify genes differentially expressed by B cells in the light and dark zones of germinal centers from mouse skin-draining lymph nodes 12 days after subcutaneous immunization with NP-OVA in alum.

Organism:

Mus musculus

Type:

Expression profiling by array

Platform:

GPL1261

8 Samples

Download data: CEL

(Submitter supplied) The expression of the Nerve growth factor receptor (NGFR) was described in follicular dendritic cells (FDCs), the major lymphoid stromal cell (LSC) compartment regulating B-cell activation within germinal centers (GCs). However, the role of NGFR in humoral response is not well defined. In this work, we have studied the effect of Ngfr KO in LNs organization and function. Ngfr KO led to spontaneous GC formation and expansion of GC B-cell compartment that were related on Ngfr depletion in non-hematopoietic radioresistant compartment. more...

Organism:

Mus musculus

Type:

Expression profiling by high throughput sequencing

Platform:

GPL17021

7 Samples

Download data: TXT