GSM1447397[Accession] - GEO DataSets

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Items: 4

Select item 2000598601.

Defining CD4 T Cell Memory by the Epigenetic Landscape of CpG DNA Methylation

(Submitter supplied) This SuperSeries is composed of the SubSeries listed below.

Organism:: Homo sapiens

Type:: Expression profiling by array; Expression profiling by high throughput sequencing; Methylation profiling by high throughput sequencing

Platforms:: GPL10999 GPL11154 GPL11532
58 Samples

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Accession:: GSE59860

ID:: 200059860

PubMed Full text in PMC Similar studies Analyze with GEO2R

Select item 2000598462.

Defining CD4 T Cell Memory by the Epigenetic Landscape of CpG DNA Methylation [RNA-Seq]

(Submitter supplied) Memory T cells are primed for rapid responses to antigen; however, the molecular mechanisms responsible for priming remain incompletely defined. CpG methylation in promoters is an epigenetic modification, which regulates gene transcription. Using targeted bisulfite sequencing, we examined methylation of 2100 genes (56,000 CpG) mapped by deep sequencing to T cell activation in human naïve and memory CD4 T cells. more...