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    eIF1A eukaryotic translation initiation factor 1A [ Drosophila melanogaster (fruit fly) ]

    Gene ID: 44260, updated on 9-Dec-2024

    Summary

    Official Symbol
    eIF1Aprovided by FlyBase
    Official Full Name
    eukaryotic translation initiation factor 1Aprovided by FlyBase
    Primary source
    FLYBASE:FBgn0026250
    Locus tag
    Dmel_CG8053
    See related
    AllianceGenome:FB:FBgn0026250
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Drosophila melanogaster
    Lineage
    Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota; Neoptera; Endopterygota; Diptera; Brachycera; Muscomorpha; Ephydroidea; Drosophilidae; Drosophila; Sophophora
    Also known as
    anon-EST:Liang-2.3; anon-EST:Posey4; CG8053; clone 2.3; D-eIF1A; D-eIF4c; Dmel\CG8053; eIF-1A; eIF-4c; EIF1A; EP(3)0935; EP935; group I; Group I; lincRNA.S7087
    Summary
    Predicted to enable translation initiation factor activity. Predicted to be involved in translational initiation. Located in cytosol and nucleoplasm. Is expressed in adult brain and adult brain cell body rind. Orthologous to human EIF1AX (eukaryotic translation initiation factor 1A X-linked) and EIF1AY (eukaryotic translation initiation factor 1A Y-linked). [provided by Alliance of Genome Resources, Dec 2024]
    Orthologs
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    Genomic context

    See eIF1A in Genome Data Viewer
    Location:
    91A1-91A1; 3-63 cM
    Exon count:
    3
    Annotation release Status Assembly Chr Location
    Release 6.54 current Release 6 plus ISO1 MT (GCF_000001215.4) 3R NT_033777.3 (18274665..18283005)
    Release 5.57 previous assembly Release 5 (GCF_000001215.2) 3R NT_033777.2 (14100387..14108727)

    Chromosome 3R - NT_033777.3Genomic Context describing neighboring genes Neighboring gene uncharacterized protein Neighboring gene Vacuolar protein sorting 39 Neighboring gene uncharacterized protein Neighboring gene uncharacterized protein Neighboring gene uncharacterized protein Neighboring gene uncharacterized protein Neighboring gene lethal (3) 05822

    Genomic regions, transcripts, and products

    Bibliography

    GeneRIFs: Gene References Into Functions

    What's a GeneRIF?

    Pathways from PubChem

    Interactions

    General gene information

    Gene Ontology Provided by FlyBase

    Function Evidence Code Pubs
    enables RNA binding  
    enables translation initiation factor activity  
    enables translation initiation factor activity  
    enables translation initiation factor activity PubMed 
    Process Evidence Code Pubs
    involved_in translation PubMed 
    involved_in translational initiation  
    involved_in translational initiation  
    involved_in translational initiation PubMed 
    Component Evidence Code Pubs
    is_active_in cytoplasm  
    located_in cytosol PubMed 
    located_in cytosol PubMed 
    part_of eukaryotic 43S preinitiation complex PubMed 
    located_in nucleoplasm PubMed 

    General protein information

    Preferred Names
    eukaryotic translation initiation factor 1A
    Names
    CG8053-PA
    CG8053-PB
    CG8053-PC
    eIF1A-PA
    eIF1A-PB
    eIF1A-PC
    eukaryotic initiation factor 1A
    eukaryotic initiation factor 4c

    NCBI Reference Sequences (RefSeq)

    NEW Try the new Transcript table

    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NT_033777.3 Reference assembly

      Range
      18274665..18283005
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_206509.1 → NP_996231.1  eukaryotic translation initiation factor 1A, isoform B [Drosophila melanogaster]

      See identical proteins and their annotated locations for NP_996231.1

      Status: REVIEWED

      UniProtKB/TrEMBL
      Q9NJB4, Q9VEA1
      Conserved Domains (1) summary
      PTZ00329
      Location:1 → 147
      PTZ00329; eukaryotic translation initiation factor 1A; Provisional
    2. NM_079989.2 → NP_524728.2  eukaryotic translation initiation factor 1A, isoform A [Drosophila melanogaster]

      See identical proteins and their annotated locations for NP_524728.2

      Status: REVIEWED

      UniProtKB/TrEMBL
      Q9NJB4, Q9VEA1
      Related
      FBpp0082994, FBtr0083572
      Conserved Domains (1) summary
      PTZ00329
      Location:1 → 147
      PTZ00329; eukaryotic translation initiation factor 1A; Provisional
    3. NM_001300457.1 → NP_001287386.1  eukaryotic translation initiation factor 1A, isoform C [Drosophila melanogaster]

      See identical proteins and their annotated locations for NP_001287386.1

      Status: REVIEWED

      UniProtKB/TrEMBL
      Q9NJB4, Q9VEA1
      Conserved Domains (1) summary
      PTZ00329
      Location:1 → 147
      PTZ00329; eukaryotic translation initiation factor 1A; Provisional
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