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Act79B Actin 79B [ Drosophila melanogaster (fruit fly) ]

Gene ID: 40444, updated on 17-Dec-2024

Summary

Official Symbol
Act79Bprovided by FlyBase
Official Full Name
Actin 79Bprovided by FlyBase
Primary source
FLYBASE:FBgn0000045
Locus tag
Dmel_CG7478
See related
AllianceGenome:FB:FBgn0000045
Gene type
protein coding
RefSeq status
REVIEWED
Organism
Drosophila melanogaster
Lineage
Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota; Neoptera; Endopterygota; Diptera; Brachycera; Muscomorpha; Ephydroidea; Drosophilidae; Drosophila; Sophophora
Also known as
143060_f_at; act 79B; ACT4; act79B; actin; Actin; ArpF; CG7478; D; Dmel\CG7478; mus79B
Summary
Predicted to be involved in mitotic cytokinesis. Predicted to be active in actin cytoskeleton. Is expressed in several structures, including adult head; adult heart; adult somatic muscle cell; male genitalia; and scutellar pulsatile organ. Human ortholog(s) of this gene implicated in Baraitser-Winter syndrome 1 and thrombocytopenia. Orthologous to human ACTB (actin beta). [provided by Alliance of Genome Resources, Dec 2024]
Orthologs
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Genomic context

See Act79B in Genome Data Viewer
Location:
79A6-79A6; 3-47 cM
Exon count:
3
Annotation release Status Assembly Chr Location
Release 6.54 current Release 6 plus ISO1 MT (GCF_000001215.4) 3L NT_037436.4 (21985210..21987190)
Release 5.57 previous assembly Release 5 (GCF_000001215.2) 3L NT_037436.3 (21978310..21980290)

Chromosome 3L - NT_037436.4Genomic Context describing neighboring genes Neighboring gene Chitin synthase 2 Neighboring gene Delta[1]-pyrroline-5-carboxylate synthase Neighboring gene uncharacterized protein Neighboring gene uncharacterized protein

Genomic regions, transcripts, and products

Interactions

General gene information

Gene Ontology Provided by FlyBase

Process Evidence Code Pubs
involved_in mitotic cytokinesis  
Component Evidence Code Pubs
is_active_in actin cytoskeleton  

General protein information

Preferred Names
actin 79B
Names
79B actin
Act79B-PA
Act79B-PB
CG7478-PA
CG7478-PB
F-actin
actin
actin-79B

NCBI Reference Sequences (RefSeq)

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NT_037436.4 Reference assembly

    Range
    21985210..21987190
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NM_001275271.1 → NP_001262200.1  actin 79B, isoform B [Drosophila melanogaster]

    See identical proteins and their annotated locations for NP_001262200.1

    Status: REVIEWED

    UniProtKB/Swiss-Prot
    P02574, Q540X7, Q9VNW5
    UniProtKB/TrEMBL
    C6TP14, M9PFZ6
    Conserved Domains (1) summary
    PTZ00281
    Location:1 → 376
    PTZ00281; actin; Provisional
  2. NM_079486.4 → NP_524210.1  actin 79B, isoform A [Drosophila melanogaster]

    See identical proteins and their annotated locations for NP_524210.1

    Status: REVIEWED

    UniProtKB/Swiss-Prot
    P02574, Q540X7, Q9VNW5
    UniProtKB/TrEMBL
    C6TP14, M9PFZ6
    Related
    FBpp0078131
    Conserved Domains (1) summary
    PTZ00281
    Location:1 → 376
    PTZ00281; actin; Provisional
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