U.S. flag

An official website of the United States government

Format

Send to:

Choose Destination

Abnormal fetal morphology

MedGen UID:
1814230
Concept ID:
C5676657
Congenital Abnormality
Synonyms: Structural fetal anomaly; Structural foetal anomaly
 
HPO: HP:0034058

Definition

Any structural anomaly of the fetus. [from HPO]

Term Hierarchy

CClinical test,  RResearch test,  OOMIM,  GGeneReviews,  VClinVar  
  • CROGVAbnormal fetal morphology

Professional guidelines

PubMed

Kosiński P, Wielgoś M
Ginekol Pol 2017;88(1):24-30. doi: 10.5603/GP.a2017.0005. PMID: 28157247
Paek B, Goldberg JD, Albanese CT
World J Surg 2003 Jan;27(1):27-37. doi: 10.1007/s00268-002-6734-5. PMID: 12557035
D'Alton ME, DeCherney AH
N Engl J Med 1993 Jan 14;328(2):114-20. doi: 10.1056/NEJM199301143280208. PMID: 8416422

Recent clinical studies

Etiology

Qin Y, Yao Y, Liu N, Wang B, Liu L, Li H, Gao T, Xu R, Wang X, Zhang F, Song J
BMC Med Genomics 2023 Oct 25;16(1):262. doi: 10.1186/s12920-023-01697-3. PMID: 37880672Free PMC Article
Peyvandi S, Rollins C
Can J Cardiol 2023 Feb;39(2):115-122. Epub 2022 Sep 27 doi: 10.1016/j.cjca.2022.09.020. PMID: 36174913Free PMC Article
Ramcharan TKW, Goff DA, Greenleaf CE, Shebani SO, Salazar JD, Corno AF
Pediatr Cardiol 2022 Oct;43(7):1409-1428. Epub 2022 Apr 23 doi: 10.1007/s00246-022-02908-x. PMID: 35460366
Koren G, Barer Y, Ornoy A
Reprod Toxicol 2020 Apr;93:230-234. Epub 2020 Mar 10 doi: 10.1016/j.reprotox.2020.03.003. PMID: 32169555
Grant P, Pearn JH
Med J Aust 1969 May 17;1(20):1016-9. doi: 10.5694/j.1326-5377.1969.tb49866.x. PMID: 5815070

Diagnosis

Qin Y, Yao Y, Liu N, Wang B, Liu L, Li H, Gao T, Xu R, Wang X, Zhang F, Song J
BMC Med Genomics 2023 Oct 25;16(1):262. doi: 10.1186/s12920-023-01697-3. PMID: 37880672Free PMC Article
Syngelaki A, Hammami A, Bower S, Zidere V, Akolekar R, Nicolaides KH
Ultrasound Obstet Gynecol 2019 Oct;54(4):468-476. doi: 10.1002/uog.20844. PMID: 31408229
Kosiński P, Wielgoś M
Ginekol Pol 2017;88(1):24-30. doi: 10.5603/GP.a2017.0005. PMID: 28157247
Lee H, Hirschl RB
Clin Perinatol 2012 Jun;39(2):xv-xvi. Epub 2012 May 18 doi: 10.1016/j.clp.2012.05.001. PMID: 22682390
Rauskolb R
J Perinat Med 1983;11(5):223-31. doi: 10.1515/jpme.1983.11.5.223. PMID: 6358450

Therapy

Dagge A, Silva LA, Jorge S, Nogueira E, Rebelo M, Pinto L
Fetal Pediatr Pathol 2022 Oct;41(5):800-806. Epub 2021 Jul 19 doi: 10.1080/15513815.2021.1948646. PMID: 34281475
Chan KY, Gilbert-Barness E, Tiller G
Pediatr Pathol Mol Med 2003 Jul-Aug;22(4):277-83. doi: 10.1080/pdp.22.4.277.283. PMID: 14692224
D'Alton ME, DeCherney AH
N Engl J Med 1993 Jan 14;328(2):114-20. doi: 10.1056/NEJM199301143280208. PMID: 8416422
Rauskolb R
J Perinat Med 1983;11(5):223-31. doi: 10.1515/jpme.1983.11.5.223. PMID: 6358450
McBride WG
Teratology 1977 Aug;16(1):79-82. doi: 10.1002/tera.1420160113. PMID: 331548

Prognosis

Zhi Y, Liu L, Wang H, Chen X, Lv Y, Cui X, Chang H, Wang Y, Cui S
Ultrasound Obstet Gynecol 2023 Nov;62(5):721-726. doi: 10.1002/uog.26254. PMID: 37204857
Lord J, McMullan DJ, Eberhardt RY, Rinck G, Hamilton SJ, Quinlan-Jones E, Prigmore E, Keelagher R, Best SK, Carey GK, Mellis R, Robart S, Berry IR, Chandler KE, Cilliers D, Cresswell L, Edwards SL, Gardiner C, Henderson A, Holden ST, Homfray T, Lester T, Lewis RA, Newbury-Ecob R, Prescott K, Quarrell OW, Ramsden SC, Roberts E, Tapon D, Tooley MJ, Vasudevan PC, Weber AP, Wellesley DG, Westwood P, White H, Parker M, Williams D, Jenkins L, Scott RH, Kilby MD, Chitty LS, Hurles ME, Maher ER; Prenatal Assessment of Genomes and Exomes Consortium
Lancet 2019 Feb 23;393(10173):747-757. Epub 2019 Jan 31 doi: 10.1016/S0140-6736(18)31940-8. PMID: 30712880Free PMC Article
Wilkinson DJ, Thiele P, Watkins A, De Crespigny L
BJOG 2012 Oct;119(11):1302-8. Epub 2012 Jul 25 doi: 10.1111/j.1471-0528.2012.03450.x. PMID: 22827258
Robson WL, Leung AK, Rogers RC
Adv Pediatr 1995;42:575-92. PMID: 8540439
Rosenberg HS
Pediatr Pathol 1990;10(1-2):103-15. doi: 10.3109/15513819009067100. PMID: 2179916

Clinical prediction guides

Karim JN, Bradburn E, Roberts N, Papageorghiou AT; ACCEPTS study
Ultrasound Obstet Gynecol 2022 Jan;59(1):11-25. doi: 10.1002/uog.23740. PMID: 34369613Free PMC Article
Koren G, Barer Y, Ornoy A
Reprod Toxicol 2020 Apr;93:230-234. Epub 2020 Mar 10 doi: 10.1016/j.reprotox.2020.03.003. PMID: 32169555
Lord J, McMullan DJ, Eberhardt RY, Rinck G, Hamilton SJ, Quinlan-Jones E, Prigmore E, Keelagher R, Best SK, Carey GK, Mellis R, Robart S, Berry IR, Chandler KE, Cilliers D, Cresswell L, Edwards SL, Gardiner C, Henderson A, Holden ST, Homfray T, Lester T, Lewis RA, Newbury-Ecob R, Prescott K, Quarrell OW, Ramsden SC, Roberts E, Tapon D, Tooley MJ, Vasudevan PC, Weber AP, Wellesley DG, Westwood P, White H, Parker M, Williams D, Jenkins L, Scott RH, Kilby MD, Chitty LS, Hurles ME, Maher ER; Prenatal Assessment of Genomes and Exomes Consortium
Lancet 2019 Feb 23;393(10173):747-757. Epub 2019 Jan 31 doi: 10.1016/S0140-6736(18)31940-8. PMID: 30712880Free PMC Article
Gournay V
Arch Cardiovasc Dis 2011 Nov;104(11):578-85. Epub 2010 Sep 21 doi: 10.1016/j.acvd.2010.06.006. PMID: 22117910
Wax JR, Mather J, Steinfeld JD, Ingardia CJ
Obstet Gynecol Surv 2000 May;55(5):303-11. doi: 10.1097/00006254-200005000-00024. PMID: 10804537

Recent systematic reviews

Carrera M, Pérez Millan F, Alcázar JL, Alonso L, Caballero M, Carugno J, Dominguez JA, Moratalla E
J Minim Invasive Gynecol 2022 Apr;29(4):465-475. Epub 2021 Oct 11 doi: 10.1016/j.jmig.2021.10.001. PMID: 34648934
Karim JN, Bradburn E, Roberts N, Papageorghiou AT; ACCEPTS study
Ultrasound Obstet Gynecol 2022 Jan;59(1):11-25. doi: 10.1002/uog.23740. PMID: 34369613Free PMC Article
Calì G, Timor-Tritsch IE, Palacios-Jaraquemada J, Monteaugudo A, Buca D, Forlani F, Familiari A, Scambia G, Acharya G, D'Antonio F
Ultrasound Obstet Gynecol 2018 Feb;51(2):169-175. doi: 10.1002/uog.17568. PMID: 28661021
Caputo C, Wood E, Jabbour L
Birth Defects Res C Embryo Today 2016 Jun;108(2):174-80. Epub 2016 Jun 13 doi: 10.1002/bdrc.21129. PMID: 27297122
Banderali G, Martelli A, Landi M, Moretti F, Betti F, Radaelli G, Lassandro C, Verduci E
J Transl Med 2015 Oct 15;13:327. doi: 10.1186/s12967-015-0690-y. PMID: 26472248Free PMC Article

Supplemental Content

Table of contents

    Clinical resources

    Practice guidelines

    • PubMed
      See practice and clinical guidelines in PubMed. The search results may include broader topics and may not capture all published guidelines. See the FAQ for details.
    • Bookshelf
      See practice and clinical guidelines in NCBI Bookshelf. The search results may include broader topics and may not capture all published guidelines. See the FAQ for details.

    Consumer resources

    Recent activity

    Your browsing activity is empty.

    Activity recording is turned off.

    Turn recording back on

    See more...