U.S. flag

An official website of the United States government

Format

Send to:

Choose Destination

Fetal choroid plexus cysts

MedGen UID:
759279
•Concept ID:
C3532166
•
Finding
Synonyms: Fetal choroid plexus cyst; Foetal choroid plexus cysts
SNOMED CT: Fetal choroid plexus cyst (462165005)
 
HPO: HP:0011426

Definition

Fetal choroid plexus cysts (CPCs) are sonographically discrete, small cysts found in the choroid plexus within the lateral cerebral ventricles of the developing fetus at 14 to 24 weeks gestation. Imaging of the choroid plexus is performed in the transverse plane of the fetal head at the same level that the lateral cerebral ventricle is evaluated. The choroid plexus should be inspected bilaterally for the presence of cysts. The size of CPCs is not of clinical relevance (PMID:16100637). [from HPO]

Term Hierarchy

CClinical test,  RResearch test,  OOMIM,  GGeneReviews,  VClinVar  
  • CROGVFetal choroid plexus cysts

Professional guidelines

PubMed

Society for Maternal-Fetal Medicine Consult Series #57: Evaluation and management of isolated soft ultrasound markers for aneuploidy in the second trimester: (Replaces Consults #10, Single umbilical artery, October 2010; #16, Isolated echogenic bowel diagnosed on second-trimester ultrasound, August 2011; #17, Evaluation and management of isolated renal pelviectasis on second-trimester ultrasound, December 2011; #25, Isolated fetal choroid plexus cysts, April 2013; #27, Isolated echogenic intracardiac focus, August 2013).
Society for Maternal-Fetal Medicine (SMFM). Electronic address: [email protected], Prabhu M, Kuller JA, Biggio JR
Am J Obstet Gynecol 2021 Oct;225(4):B2-B15. Epub 2021 Jun 23 doi: 10.1016/j.ajog.2021.06.079. PMID: 34171388
Management of fetal choroid plexus cysts.
Burch D
Br J Obstet Gynaecol 1998 Feb;105(2):245-6. doi: 10.1111/j.1471-0528.1998.tb10070.x. PMID: 9501800
Management of fetal choroid plexus cysts.
Gupta JK, Khan KS, Thornton JG, Lilford RJ
Br J Obstet Gynaecol 1997 Aug;104(8):881-6. doi: 10.1111/j.1471-0528.1997.tb14345.x. PMID: 9255077

Recent clinical studies

Etiology

Society for Maternal-Fetal Medicine Consult Series #57: Evaluation and management of isolated soft ultrasound markers for aneuploidy in the second trimester: (Replaces Consults #10, Single umbilical artery, October 2010; #16, Isolated echogenic bowel diagnosed on second-trimester ultrasound, August 2011; #17, Evaluation and management of isolated renal pelviectasis on second-trimester ultrasound, December 2011; #25, Isolated fetal choroid plexus cysts, April 2013; #27, Isolated echogenic intracardiac focus, August 2013).
Society for Maternal-Fetal Medicine (SMFM). Electronic address: [email protected], Prabhu M, Kuller JA, Biggio JR
Am J Obstet Gynecol 2021 Oct;225(4):B2-B15. Epub 2021 Jun 23 doi: 10.1016/j.ajog.2021.06.079. PMID: 34171388
Management of fetal choroid plexus cysts.
Gupta JK, Khan KS, Thornton JG, Lilford RJ
Br J Obstet Gynaecol 1997 Aug;104(8):881-6. doi: 10.1111/j.1471-0528.1997.tb14345.x. PMID: 9255077
Fetal choroid plexus cysts--is a genetic evaluation indicated?
Sharony R
Prenat Diagn 1997 Jun;17(6):519-24. PMID: 9203210
Clinical significance of fetal choroid plexus cysts.
Gupta JK, Cave M, Lilford RJ, Farrell TA, Irving HC, Mason G, Hau CM
Lancet 1995 Sep 16;346(8977):724-9. doi: 10.1016/s0140-6736(95)91502-8. PMID: 7658872
Fetal choroid plexus cysts: a prospective study and review of the literature.
Twining P, Zuccollo J, Clewes J, Swallow J
Br J Radiol 1991 Feb;64(758):98-102. doi: 10.1259/0007-1285-64-758-98. PMID: 1825933

Diagnosis

Society for Maternal-Fetal Medicine Consult Series #57: Evaluation and management of isolated soft ultrasound markers for aneuploidy in the second trimester: (Replaces Consults #10, Single umbilical artery, October 2010; #16, Isolated echogenic bowel diagnosed on second-trimester ultrasound, August 2011; #17, Evaluation and management of isolated renal pelviectasis on second-trimester ultrasound, December 2011; #25, Isolated fetal choroid plexus cysts, April 2013; #27, Isolated echogenic intracardiac focus, August 2013).
Society for Maternal-Fetal Medicine (SMFM). Electronic address: [email protected], Prabhu M, Kuller JA, Biggio JR
Am J Obstet Gynecol 2021 Oct;225(4):B2-B15. Epub 2021 Jun 23 doi: 10.1016/j.ajog.2021.06.079. PMID: 34171388
Fetal choroid plexus cysts: are we there yet?
Walkinshaw SA
Prenat Diagn 2000 Aug;20(8):657-62. PMID: 10951477
Isolated fetal choroid plexus cysts: not an indication for genetic diagnosis?
Sohn C, Gast AS, Krapfl E
Fetal Diagn Ther 1997 Sep-Oct;12(5):255-9. doi: 10.1159/000264480. PMID: 9430203
Clinical significance of fetal choroid plexus cysts.
Gupta JK, Cave M, Lilford RJ, Farrell TA, Irving HC, Mason G, Hau CM
Lancet 1995 Sep 16;346(8977):724-9. doi: 10.1016/s0140-6736(95)91502-8. PMID: 7658872
Choroid plexus cysts and chromosomal defects.
Thorpe-Beeston JG, Gosden CM, Nicolaides KH
Br J Radiol 1990 Oct;63(754):783-6. doi: 10.1259/0007-1285-63-754-783. PMID: 2242475

Therapy

Sonography of fetal choroid plexus cysts: detection depends on cyst size and gestational age.
Turner SR, Samei E, Hertzberg BS, DeLong DM, Vargas-Voracek R, Singer A, Maynor CH, Kliewer MA
J Ultrasound Med 2003 Nov;22(11):1219-27. doi: 10.7863/jum.2003.22.11.1219. PMID: 14620893

Prognosis

Isolated fetal choroid plexus cysts: not an indication for genetic diagnosis?
Sohn C, Gast AS, Krapfl E
Fetal Diagn Ther 1997 Sep-Oct;12(5):255-9. doi: 10.1159/000264480. PMID: 9430203
Isolated fetal choroid plexus cysts and trisomy 18: a review and meta-analysis.
Gross SJ, Shulman LP, Tolley EA, Emerson DS, Felker RE, Simpson JL, Elias S
Am J Obstet Gynecol 1995 Jan;172(1 Pt 1):83-7. doi: 10.1016/0002-9378(95)90088-8. PMID: 7847564
Clinical significance of fetal choroid plexus cysts.
Gupta JK, Cave M, Lilford RJ, Farrell TA, Irving HC, Mason G, Hau CM
Lancet 1995 Sep 16;346(8977):724-9. doi: 10.1016/s0140-6736(95)91502-8. PMID: 7658872
Choroid plexus cysts in the fetus: a benign anatomic variant or pathologic entity? Report of 41 cases and review of the literature.
Chitkara U, Cogswell C, Norton K, Wilkins IA, Mehalek K, Berkowitz RL
Obstet Gynecol 1988 Aug;72(2):185-9. PMID: 3292976
Fetal choroid plexus cysts: prevalence, clinical significance, and sonographic appearance.
DeRoo TR, Harris RD, Sargent SK, Denholm TA, Crow HC
AJR Am J Roentgenol 1988 Dec;151(6):1179-81. doi: 10.2214/ajr.151.6.1179. PMID: 3055893

Clinical prediction guides

Sonography of fetal choroid plexus cysts: detection depends on cyst size and gestational age.
Turner SR, Samei E, Hertzberg BS, DeLong DM, Vargas-Voracek R, Singer A, Maynor CH, Kliewer MA
J Ultrasound Med 2003 Nov;22(11):1219-27. doi: 10.7863/jum.2003.22.11.1219. PMID: 14620893
Fetal choroid plexus cysts--is a genetic evaluation indicated?
Sharony R
Prenat Diagn 1997 Jun;17(6):519-24. PMID: 9203210
Isolated fetal choroid plexus cysts and trisomy 18: a review and meta-analysis.
Gross SJ, Shulman LP, Tolley EA, Emerson DS, Felker RE, Simpson JL, Elias S
Am J Obstet Gynecol 1995 Jan;172(1 Pt 1):83-7. doi: 10.1016/0002-9378(95)90088-8. PMID: 7847564
Clinical significance of fetal choroid plexus cysts.
Gupta JK, Cave M, Lilford RJ, Farrell TA, Irving HC, Mason G, Hau CM
Lancet 1995 Sep 16;346(8977):724-9. doi: 10.1016/s0140-6736(95)91502-8. PMID: 7658872
Choroid plexus cysts in the fetus: a benign anatomic variant or pathologic entity? Report of 41 cases and review of the literature.
Chitkara U, Cogswell C, Norton K, Wilkins IA, Mehalek K, Berkowitz RL
Obstet Gynecol 1988 Aug;72(2):185-9. PMID: 3292976

Supplemental Content

Table of contents

    Clinical resources

    Practice guidelines

    • PubMed
      See practice and clinical guidelines in PubMed. The search results may include broader topics and may not capture all published guidelines. See the FAQ for details.

    Consumer resources

    Reviews

    Related information

    • PMC Articles
      Related information in PubMed Central Links
    • PubMed
      Related literature resources in PubMed

    Recent activity

    Clear Turn Off Turn On

    Your browsing activity is empty.

    Activity recording is turned off.

    Turn recording back on

    See more...