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| Status |
Public on Aug 29, 2018 |
| Title |
Gene expression data from endothelial cells isolated from DNFB-treated ears of mice with inducible endothelial-specific overexpression of constitutively active Notch1 intracellular domain |
| Organism |
Mus musculus |
| Experiment type |
Expression profiling by array
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| Summary |
Notch1 is a key regulator of endothelial cell behaviour. This experiment was designed to identify genes regulated by Notch1 signaling in inflammatory activated mouse endothelial cells.
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| Overall design |
NICD1-iEC-OE mice were treated with 5 daily tamoxifen injections to promote endothelial-specific overexpression of constitutively active Notch1 intracellular domain and used in the DNFB-induced contact hypersensitivity model. Endothelial cells (CD31+ CD45- Ter119-) were isolated from DNFB-treated ears by flow cytometry and submitted for transcriptional analysis.
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| Contributor(s) |
Edelmann RJ, Diegues-Hurtado R, Haraldsen G, Adams RH, Hol J |
| Citation(s) |
29449332 |
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| Submission date |
Aug 24, 2016 |
| Last update date |
Aug 29, 2018 |
| Contact name |
Guttorm Haraldsen |
| E-mail(s) |
[email protected]
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| Organization name |
Oslo University Hospital
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| Department |
Department for Pathology
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| Lab |
LIIPAT
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| Street address |
Sognsvannsveien 20
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| City |
OSLO |
| State/province |
OSLO |
| ZIP/Postal code |
0027 |
| Country |
Norway |
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| Platforms (1) |
| GPL17400 |
[MoGene-2_1-st] Affymetrix Mouse Gene 2.1 ST Array [transcript (gene) version] |
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| Samples (20)
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| GSM2290191 |
Endothelial cells isolated from DNFB-treated ear, control mouse, replicate 1 |
| GSM2290192 |
Endothelial cells isolated from vehicle-treated ear, control mouse, replicate 1 |
| GSM2290193 |
Endothelial cells isolated from DNFB-treated ear, control mouse, replicate 2 |
| GSM2290194 |
Endothelial cells isolated from vehicle-treated ear, control mouse, replicate 2 |
| GSM2290195 |
Endothelial cells isolated from DNFB-treated ear, control mouse, replicate 3 |
| GSM2290196 |
Endothelial cells isolated from vehicle-treated ear, control mouse, replicate 3 |
| GSM2290197 |
Endothelial cells isolated from DNFB-treated ear, control mouse, replicate 4 |
| GSM2290198 |
Endothelial cells isolated from vehicle-treated ear, control mouse, replicate 4 |
| GSM2290199 |
Endothelial cells isolated from DNFB-treated ear, control mouse, replicate 5 |
| GSM2290200 |
Endothelial cells isolated from vehicle-treated ear, control mouse, replicate 5 |
| GSM2290201 |
Endothelial cells isolated from DNFB-treated ear, control mouse, replicate 6 |
| GSM2290202 |
Endothelial cells isolated from vehicle-treated ear, control mouse, replicate 6 |
| GSM2290203 |
Endothelial cells isolated from DNFB-treated ear, NICD1-EC-OE mouse, replicate 1 |
| GSM2290204 |
Endothelial cells isolated from vehicle-treated ear, NICD1-EC-OE mouse, replicate 1 |
| GSM2290205 |
Endothelial cells isolated from DNFB-treated ear, NICD1-EC-OE mouse, replicate 2 |
| GSM2290206 |
Endothelial cells isolated from vehicle-treated ear, NICD1-EC-OE mouse, replicate 2 |
| GSM2290207 |
Endothelial cells isolated from DNFB-treated ear, NICD1-EC-OE mouse, replicate 3 |
| GSM2290208 |
Endothelial cells isolated from vehicle-treated ear, NICD1-EC-OE mouse, replicate 3 |
| GSM2290209 |
Endothelial cells isolated from DNFB-treated ear, NICD1-EC-OE mouse, replicate 4 |
| GSM2290210 |
Endothelial cells isolated from vehicle-treated ear, NICD1-EC-OE mouse, replicate 4 |
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| This SubSeries is part of SuperSeries: |
| GSE85987 |
Inhibition of endothelial Notch signaling attenuates inflammation |
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| Relations |
| BioProject |
PRJNA339957 |
| Supplementary file |
Size |
Download |
File type/resource |
| GSE85992_RAW.tar |
89.2 Mb |
(http)(custom) |
TAR (of CEL) |
| Processed data included within Sample table |
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