|
| Status |
Public on Nov 06, 2012 |
| Title |
Chromatin proteins linked to dosage compensation in Drosophila captured by ChIP-mass spectrometry |
| Organism |
Drosophila melanogaster |
| Experiment type |
Genome binding/occupancy profiling by high throughput sequencing
|
| Summary |
We report the usage of ChIP-mass spectrometry in identifying proteins and histone modifications involved in Drosophila dosage compensation. We identified a chromatin targeting factor, CG4747, that is involved in recognition of H3K36me3 and robust recruitment of the Drosophila MSL complex to its correct targets on the male X chromosome.
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| |
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| Overall design |
ChIP-seq with PAP antibody of Drosophila larvae expressing C-terminally TAP-tagged CG4747.
|
| |
|
| Contributor(s) |
Wang C, Kuroda M |
| Citation missing |
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| |
| Submission date |
Nov 05, 2012 |
| Last update date |
May 15, 2019 |
| Contact name |
Peter Kharchenko |
| Organization name |
Harvard Medical School
|
| Department |
DBMI
|
| Lab |
Kharchenko
|
| Street address |
10 Shattuck St.
|
| City |
Boston |
| State/province |
MA |
| ZIP/Postal code |
02115 |
| Country |
USA |
| |
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| Platforms (1) |
| GPL13304 |
Illumina HiSeq 2000 (Drosophila melanogaster) |
|
| Samples (8)
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| Relations |
| BioProject |
PRJNA178936 |
| SRA |
SRP017042 |
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