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Status |
Public on Oct 01, 2013 |
Title |
Expression data from endthelial cells in ductus arteriosus and aorta in rat fetuses or neonates |
Organism |
Rattus norvegicus |
Experiment type |
Expression profiling by array
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Summary |
Endothelial cells (Ecs) lining the blood vessels have been known to have a variety of functions and play a central role in homeostasis of the circulatory system. Since ductus arteriosus (DA) has unique characteristics comparing other vessels, we hypothesized that ECs were the primary target to investigate the molecular mechanisms of DA-specific vasoconstriction and vascular remodeling.
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Overall design |
Using fluorescence activated cell sorter, we isolated ECs from pooled tissues from the DA or the aorta of Wistar rat fetuses on the 21st day of gestation (e21) or 30 minutes after birth (day0). We prepared 3 sets of ECs in each tissues and time points. We aimed to compare the gene profiles of DA and the aorta at each developmental stage.
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Contributor(s) |
Yokota T, Minamisawa S |
Citation(s) |
24086288 |
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Submission date |
Aug 30, 2012 |
Last update date |
Dec 31, 2013 |
Contact name |
Norika Mengchia Liu |
E-mail(s) |
[email protected]
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Organization name |
Waseda University
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Department |
Dep. Life science & Medical Bioscience
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Street address |
2-2, Wakamatsu-cho
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City |
Shinjuku-ku |
State/province |
Tokyo |
ZIP/Postal code |
162-8480 |
Country |
Japan |
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Platforms (1) |
GPL6247 |
[RaGene-1_0-st] Affymetrix Rat Gene 1.0 ST Array [transcript (gene) version] |
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Samples (12)
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GSM995341 |
term fetuses, DA Ecs-rep1 |
GSM995342 |
term fetuses, DA Ecs-rep2 |
GSM995343 |
term fetuses, DA Ecs-rep3 |
GSM995344 |
30 mins after birth neonates, aorta Ecs-rep1 |
GSM995345 |
30 mins after birth neonates, aorta Ecs-rep2 |
GSM995346 |
30 mins after birth neonates, aorta Ecs-rep3 |
GSM995347 |
30 mins after birth neonates, DA Ecs-rep1 |
GSM995348 |
30 mins after birth neonates, DA Ecs-rep2 |
GSM995349 |
30 mins after birth neonates, DA Ecs-rep3 |
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Relations |
BioProject |
PRJNA174184 |
Supplementary file |
Size |
Download |
File type/resource |
GSE40500_RAW.tar |
45.4 Mb |
(http)(custom) |
TAR (of CEL) |
Processed data included within Sample table |
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