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| Status |
Public on Oct 10, 2013 |
| Title |
TET2 loss-of-function mutations associate with a DNA hypermethylation signature in diffuse large B-cell lymphoma (mRNA) |
| Organism |
Homo sapiens |
| Experiment type |
Expression profiling by array
|
| Summary |
Global gene expression in TET2 mutant and Wild type patients. We performed an integrated analysis of global DNA methylation and gene expression data to investigate the effects of DNA hypermethylation on gene expression.
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| Overall design |
Total RNA was isolated from 4 TET2mut and 5 TET2wt were isolated using standard RNAeasy kit protocol (Qiagen). Their gene expression profiles were obtained using the[HuGene-1_0-st] Affymetrix.
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| Contributor(s) |
Asmar F, Punj V, Christensen J, Pedersen MT, Pedersen A, Nielsen AB, Hother C, Ralfkiaer U, Brown PD, Ralfkiaer E, Helin K, Gronbaek K |
| Citation(s) |
23831920 |
| |
| Submission date |
Apr 17, 2012 |
| Last update date |
Jul 26, 2018 |
| Contact name |
Vasu Punj |
| E-mail(s) |
[email protected]
|
| Organization name |
USC
|
| Street address |
Biggy Street
|
| City |
Los Angeles |
| State/province |
CA |
| ZIP/Postal code |
90033 |
| Country |
USA |
| |
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| Platforms (1) |
| GPL6244 |
[HuGene-1_0-st] Affymetrix Human Gene 1.0 ST Array [transcript (gene) version] |
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| Samples (9)
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| This SubSeries is part of SuperSeries: |
| GSE37365 |
TET2 loss-of-function mutations associate with a DNA hypermethylation signature in diffuse large B-cell lymphoma |
|
| Relations |
| BioProject |
PRJNA159821 |
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