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| Status |
Public on Mar 01, 2024 |
| Title |
A human iPSC-derived multilineage liver organoid model containing Kupffer cells to study human sepsis-associated liver dysfunction [KuLOs] |
| Organism |
Homo sapiens |
| Experiment type |
Expression profiling by high throughput sequencing
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| Summary |
To recapitulate the pathology of human septic liver, we established hiPSC-derived liver organoids containing Kupffer cells (KuLOs).
We performed gene expression profiling analysis using data obtained from RNA-seq of KuLOs with/without LPS/IFNr stimulation and the KuLOs during recovery after endotoxin elimination.
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| Overall design |
Comparative gene expression profiling analysis of RNA-seq data for KuLOs.
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| Web link |
https://pubmed.ncbi.nlm.nih.gov/38451817/
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| Contributor(s) |
Li Y, Nie Y, Taniguchi H |
| Citation(s) |
38451817 |
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| Submission date |
May 25, 2023 |
| Last update date |
Jun 02, 2024 |
| Contact name |
Yang Li |
| E-mail(s) |
[email protected]
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| Organization name |
The University of Tokyo
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| Street address |
Shirokanedai 4-6-1
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| City |
Minato |
| State/province |
Tokyo |
| ZIP/Postal code |
1080071 |
| Country |
Japan |
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| Platforms (1) |
| GPL17303 |
Ion Torrent Proton (Homo sapiens) |
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| Samples (10)
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| GSM7429230 |
KuLOs, septic, rep2 |
| GSM7429231 |
KuLOs, recovery D1, rep1 |
| GSM7429232 |
KuLOs, recovery D1, rep2 |
| GSM7429233 |
KuLOs, recovery D2, rep1 |
| GSM7429234 |
KuLOs, recovery D2, rep2 |
| GSM7429235 |
KuLOs, recovery D3, rep1 |
| GSM7429236 |
KuLOs, recovery D3, rep2 |
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| This SubSeries is part of SuperSeries: |
| GSE233539 |
A human iPSC-derived multilineage liver organoid model containing Kupffer cells to study human sepsis-associated liver dysfunction |
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| Relations |
| BioProject |
PRJNA976337 |
| Supplementary file |
Size |
Download |
File type/resource |
| GSE233483_Combined_processed_data_KuLOs.txt.gz |
1.2 Mb |
(ftp)(http) |
TXT |
SRA Run Selector |
| Raw data are available in SRA |
| Processed data are available on Series record |
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