|
| Status |
Public on Jun 28, 2023 |
| Title |
Transcriptomic analysis reveals distinct adaptive molecular mechanism in the hippocampal CA3 from rats susceptible or not-susceptible to hyperthermia-induced seizures |
| Organism |
Rattus norvegicus |
| Experiment type |
Non-coding RNA profiling by array
|
| Summary |
This study aimed to identify the genomic differences - through differential gene expression, miRNAs, and WGCNA transcriptional modules among animals with or without seizure after insult and non-insulted controls.
|
| |
|
| Overall design |
Use of a rat (Rattus norvegicus) model of hyperthermia-induced seizure to characterize the genomic mechanism underlying febrile seizures in epilepsy. The aim of the study is to identify the genomic differences in hippocampal ventral CA3 region - through differential gene expression, miRNAs, and WGCNA transcriptional modules among animals with (HS) or without (HNS) seizure after insult and non-insulted controls (CT). Here, samples from the animal of all groups in the P30 time-interval.
|
| |
|
| Contributor(s) |
Bando SY, Bertonha FB, Menezes PH, Takahara AK, Khaled NA, Santos P, Junqueira MS, Cesar RM Jr, Moreira-Filho CA |
| Citation(s) |
37355705 |
| |
| Submission date |
Apr 14, 2023 |
| Last update date |
Aug 09, 2023 |
| Contact name |
Carlos Alberto Moreira-Filho |
| E-mail(s) |
[email protected]
|
| Phone |
55-11-3061-8449
|
| Organization name |
Faculdade de Medicina da Universidade de Sao Paulo
|
| Department |
Departments of Pediatrics
|
| Lab |
LIM36
|
| Street address |
Av. Dr. Eneas Carvalho de Aguiar 647
|
| City |
Sao Paulo |
| State/province |
SP |
| ZIP/Postal code |
05403-900 |
| Country |
Brazil |
| |
|
| Platforms (1) |
| GPL14746 |
Agilent-028282 Whole Rat Genome Microarray 4x44K v3 (Probe Name version) |
|
| Samples (15)
|
|
| This SubSeries is part of SuperSeries: |
| GSE229760 |
Transcriptomic analysis reveals distinct adaptive molecular mechanism in the hippocampal CA3 from rats susceptible or not-susceptible to hyperthermia-induced seizures |
|
| Relations |
| BioProject |
PRJNA955782 |
Less...
More...