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| Status |
Public on Sep 24, 2022 |
| Title |
Development of gene expression signatures for lnc-URIDS knock down rat dermal fibroblast |
| Organism |
Rattus norvegicus |
| Experiment type |
Expression profiling by array
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| Summary |
In previous study we found that Lnc-URIDS increased in diabetic dermal fibroblast and delayed wound healing.To further verify the roles of lnc-URIDS in fibroblast during wound heaing, A lnc-URIDS shRNA lentivirus and a control lentivirus were transfected into rat dermal fibroblast respectively (three independent replicates for each group) for 48h. Then, differential expressed genes between Control fibroblast and Lnc-URIDS knockdown fibroblast were detected by using microarray expression profiling though Agilent rat 4 x 44K gene expression microarrays (Agilent Technologies, Santa Clara, CA) .
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| Overall design |
Three replicate samples in control group and KD group.
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| Contributor(s) |
Hu M, Yan L, Ren M |
| Citation missing |
Has this study been published? Please login to update or notify GEO. |
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| Submission date |
Sep 23, 2022 |
| Last update date |
Sep 26, 2022 |
| Contact name |
Meng Ren |
| E-mail(s) |
[email protected]
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| Phone |
+862081332286
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| Organization name |
Sun Yat-sen Memorial Hospital, Sun Yat-sen University
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| Department |
endocrinology department
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| Street address |
107 Yanjiang West Road
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| City |
guangzhou |
| ZIP/Postal code |
510120 |
| Country |
China |
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| Platforms (1) |
| GPL14746 |
Agilent-028282 Whole Rat Genome Microarray 4x44K v3 (Probe Name version) |
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| Samples (6)
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| GSM6598127 |
Rat dermal fibroblast, 48h, control lentivirus, replicate1 |
| GSM6598128 |
Rat dermal fibroblast, 48h, control lentivirus, replicate2 |
| GSM6598129 |
Rat dermal fibroblast, 48h, control lentivirus, replicate3 |
| GSM6598130 |
Rat dermal fibroblast, 48h, lnc-URIDS shRNA lentivirus, replicate1 |
| GSM6598131 |
Rat dermal fibroblast, 48h, lnc-URIDS shRNA lentivirus, replicate2 |
| GSM6598132 |
Rat dermal fibroblast, 48h, lnc-URIDS shRNA lentivirus, replicate3 |
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| Relations |
| BioProject |
PRJNA883664 |
| Supplementary file |
Size |
Download |
File type/resource |
| GSE214034_RAW.tar |
12.7 Mb |
(http)(custom) |
TAR (of TXT) |
| GSE214034_processed_data.xls.gz |
6.6 Mb |
(ftp)(http) |
XLS |
| Processed data included within Sample table |
| Processed data are available on Series record |
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