|
| Status |
Public on Dec 31, 2012 |
| Title |
Effect of IL-1b treatment on cultured rat aortic smooth muscle cells |
| Organism |
Rattus norvegicus |
| Experiment type |
Expression profiling by array
|
| Summary |
IL-1 plays an important role in atherosclerosis, and alters expression of a number of genes involved in atherosclerotic plaque development and progression. Smooth muscle cells play important roles in atherosclerotic plaque formation and stability, so this study was undertaken to determine the global effects of IL-1b on gene expression in smooth muscle cells in vitro.
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| |
|
| Overall design |
Cultured rat aortic smooth muscle cells were treated with IL-1b (2.5 ng/mL) or vehicle (0.1% BSA) for 24 hours prior to harvest.
|
| |
|
| Contributor(s) |
Owens GK, Alexander MR |
| Citation(s) |
22201681 |
| |
| Submission date |
Apr 20, 2010 |
| Last update date |
Jul 31, 2017 |
| Contact name |
Gary Owens |
| Organization name |
University of Virginia
|
| Department |
Molecular Physiology and Biological Physics
|
| Lab |
Gary Owens' Laboratory
|
| Street address |
415 Lane Road
|
| City |
Charlottesville |
| State/province |
VA |
| ZIP/Postal code |
22908 |
| Country |
USA |
| |
|
| Platforms (1) |
| GPL1355 |
[Rat230_2] Affymetrix Rat Genome 230 2.0 Array |
|
| Samples (4)
|
| GSM534835 |
IL-1b (2.5 ng/mL) treated SMCs rep2 |
|
| Relations |
| BioProject |
PRJNA126405 |
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