|
| Status |
Public on Jan 05, 2010 |
| Title |
Chromosomal aberrations of human bladder cancer cell lines |
| Organism |
Homo sapiens |
| Experiment type |
Genome variation profiling by genome tiling array
|
| Summary |
In order to identify putative targets in human bladder cancer (BC) cell lines, a survey of parallel chromosomal alterations and gene expression studies in 5 BC cell lines were performed using array-CGH and microarray techniques. Predominantly gained loci were observed at 1q21.3, 8q24.2, 8q24.3, 11q13.3, and 20q13.33 in four or more of the cell lines. The focus was on the typical gain locus of 8q24.3, which has not been studied in detail for BC.
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| |
|
| Overall design |
Genomic DNAs from 5 cell lines and normal diploid cells were subjected to array CGH analysis to identify genomic alterations in the each cell lines. These DNAs were labeled with Cy5 and Cy3, respectively.
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| |
|
| Contributor(s) |
Seki N |
| Citation(s) |
21063397 |
| |
| Submission date |
Dec 31, 2009 |
| Last update date |
Oct 26, 2016 |
| Contact name |
Naohiko Seki |
| E-mail(s) |
[email protected]
|
| Phone |
+81-43-226-2971
|
| Organization name |
Chiba University
|
| Department |
Functional Genomics
|
| Street address |
1-8-1, Inohana
|
| City |
Chiba |
| State/province |
Chiba |
| ZIP/Postal code |
260-8670 |
| Country |
Japan |
| |
|
| Platforms (1) |
| GPL4091 |
Agilent-014693 Human Genome CGH Microarray 244A (Feature number version) |
|
| Samples (5)
|
| GSM492490 |
BOY cell line relative to normal diploid cell |
| GSM492491 |
J82 cell line relative to normal diploid cell |
| GSM492492 |
KK47 cell line relative to normal diploid cell |
| GSM492493 |
T24 cell line relative to normal diploid cell |
| GSM492494 |
UMUC cell line relative to normal diploid cell |
|
| Relations |
| BioProject |
PRJNA121907 |
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