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Series GSE17459 Query DataSets for GSE17459
Status Public on Jan 13, 2010
Title Down's syndrome with acute lymphoblastic pediatric leukemia (DS-ALL)
Organism Homo sapiens
Experiment type Expression profiling by array
Summary DS-ALL is a highly heterogeneous disease with predominance of an aberrant exp. of CRLF2 cooperating with mutated JAK2

Acute lymphoblastic pediatric leukemia specimens of Down's syndrome are examined for gene expression profiles and specific genetic aberrations. Gene expression profiling and specific genetic variation analysis identify novel pathways involved in DS-ALL pathogenesis.
 
Overall design Gene expression profile analysis and specific genetic data are integrated to find characteristics of DS-ALL's
 
Contributor(s) Herzberg L, te Kronnie G, Bourquin J, Kempski H
Citation(s) 19965641
Submission date Jul 31, 2009
Last update date Mar 25, 2019
Contact name Libi Hertzberg
Organization name Weizmann Institute of Science
Street address Herzel 145
City Rehovot
ZIP/Postal code 76100
Country Israel
 
Platforms (2)
GPL96 [HG-U133A] Affymetrix Human Genome U133A Array
GPL570 [HG-U133_Plus_2] Affymetrix Human Genome U133 Plus 2.0 Array
Samples (119)
GSM435320 DS-ALL, AIEOP data set (SI-DS-ALL-73)
GSM435321 DS-ALL, AIEOP data set (SI-DS-ALL-84)
GSM435322 DS-ALL, AIEOP data set (SI-DS-ALL-69)
Relations
BioProject PRJNA118735

Download family Format
SOFT formatted family file(s) SOFTHelp
MINiML formatted family file(s) MINiMLHelp
Series Matrix File(s) TXTHelp

Supplementary file Size Download File type/resource
GSE17459_DSALL_mutational_analysis.pdf.gz 71.1 Kb (ftp)(http) PDF
GSE17459_RAW.tar 482.7 Mb (http)(custom) TAR (of CEL)
Processed data included within Sample table
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