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| Status |
Public on May 25, 2021 |
| Title |
Next Generation Sequencing Facilitates Quantitative Analysis of human multiple myeloma derived CD84 activated G-MDSCs or IgG (control) treated G-MDSCs |
| Organism |
Homo sapiens |
| Experiment type |
Expression profiling by high throughput sequencing
|
| Summary |
Purpose: Next-generation sequencing (NGS) has revolutionized systems-based analysis of cellular pathways. The goals of this study are to compare CD84 activated to control treated primary human G-MDSCs from multiple myeloma patients transcriptome profiling (RNA-seq) to understand the role of CD84 on these cells
Methods: mRNA profiles from sorted G-MDSCs from patient bone marrow samples were generated by deep sequencing, in triplicate, using a bulk adaptation of the MARS-Seq protocol.
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| |
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| Overall design |
mRNA profiles of human multiple myeloma derived CD84 activated G-MDSCs or IgG (control) treated G-MDSCs
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| |
|
| Contributor(s) |
Lewinsky H, Shachar I |
| Citation(s) |
33465053 |
| |
| Submission date |
Jan 12, 2021 |
| Last update date |
May 25, 2021 |
| Contact name |
Idit Shachar |
| E-mail(s) |
[email protected]
|
| Organization name |
Weizmann Institute of science
|
| Department |
Immunology
|
| Lab |
Prof. Idit Shachar
|
| Street address |
Herzl 234
|
| City |
Rehovot |
| ZIP/Postal code |
7610001 |
| Country |
Israel |
| |
|
| Platforms (1) |
| GPL18573 |
Illumina NextSeq 500 (Homo sapiens) |
|
| Samples (6)
|
| GSM5016396 |
patient 1 CD84 activation sorted G-MDSCs |
| GSM5016397 |
patient 2 CD84 activation sorted G-MDSCs |
| GSM5016398 |
patient 3 CD84 activation sorted G-MDSCs |
| GSM5016399 |
patient 1 IgG activation sorted G-MDSCs |
| GSM5016400 |
patient 2 IgG activation sorted G-MDSCs |
| GSM5016401 |
patient 3 IgG activation sorted G-MDSCs |
|
| Relations |
| BioProject |
PRJNA691508 |
| SRA |
SRP301410 |
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