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| Status |
Public on Feb 21, 2020 |
| Title |
Induction of steatohepatitis and liver tumorigenesis by enforced Snail expression in hepatocytes |
| Organism |
Mus musculus |
| Experiment type |
Expression profiling by array
|
| Summary |
Enforced Snail expression in hepatocytes is sufficient for induction of steatohepatitis and liver tumorigenesis through disruption of the biliary canaliculus and bile acid homeostasis in the liver.
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| Overall design |
We conducted comparative global gene expression analyses between the liver of wild-type (WT) mouse and that of Alb-Cre;CAG-floxed neo-Snail mouse.
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| Contributor(s) |
Miura S, Suzuki A |
| Citation(s) |
32188584 |
| |
| Submission date |
Nov 27, 2019 |
| Last update date |
May 25, 2020 |
| Contact name |
Atsushi Suzuki |
| Organization name |
Medical Institute of Bioreguration, Kyushu University
|
| Department |
Division of Organogenesis and Regeneration
|
| Street address |
3-1-1 Maidashi, Higashi-ku
|
| City |
Fukuoka |
| State/province |
Fukuoka |
| ZIP/Postal code |
812-8582 |
| Country |
Japan |
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| Platforms (1) |
| GPL11202 |
Agilent-026655 Whole Mouse Genome Microarray 4x44K v2 (Probe Name version) |
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| Samples (2) |
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| Relations |
| BioProject |
PRJNA592136 |
