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| Status |
Public on Jun 27, 2019 |
| Title |
Gene expression profile in hearts of WT and endothelial S1pr1 knock-out mice 5 days after myocardial infarction |
| Organism |
Mus musculus |
| Experiment type |
Expression profiling by array
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| Summary |
High-throughout RNA microarray results revealed different gene expression, including arg1, VEGF, TGF-beta, and IL-10, in ischemic myocardium of endothelial S1pr1 knock-out mice, compared to WT mice.
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| Overall design |
We generated endothelial S1pr1 knock-out mice, and induced acute myocardial infarction by ligation of the left anterior descending coronary arteries in these mice and their corresponding WT mice. We applied high-throughout RNA microarray to study gene expression profile in the hearts 5 days after myocardial infarction in WT and endothelial S1pr1 conditional knock-out mice.
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| Contributor(s) |
Lin Z, Yashu K |
| Citation missing |
Has this study been published? Please login to update or notify GEO. |
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| Submission date |
Jun 26, 2019 |
| Last update date |
Jun 29, 2019 |
| Contact name |
kuang ya shu |
| E-mail(s) |
[email protected]
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| Phone |
15901901743
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| Organization name |
Shanghai East Hospital, Tongji University School of Medicine
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| Department |
Key Laboratory of Arrhythmias of the Ministry of Education of China, Research Center for Translational Medicine
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| Lab |
Key Laboratory of Arrhythmias of the Ministry of Education of China
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| Street address |
150 Jimo Rd, Pudong New District, Shanghai
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| City |
Shanghai |
| State/province |
Shanghai |
| ZIP/Postal code |
200120 |
| Country |
China |
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| Platforms (1) |
| GPL11202 |
Agilent-026655 Whole Mouse Genome Microarray 4x44K v2 (Probe Name version) |
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| Samples (4)
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| GSM3906200 |
Vivo heart_AMI_5day_VE-Cad-Cre-S1pr1 fl/fl_KO4_rep1 |
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| Relations |
| BioProject |
PRJNA551257 |
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