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| Status |
Public on Sep 19, 2019 |
| Title |
Expression data from stroke patients blood samples |
| Organism |
Homo sapiens |
| Experiment type |
Expression profiling by array
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| Summary |
Ischemic stroke can be classified depending on its etiology as cardioembolic (CE), large-vessel atheroesclerotic (LAA), lacunar, other or cryptogenic. Our aim was to identify gene expression changes that could differentiate CE and LAA stroke in order to guide the optimal secondary treatment .
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| Overall design |
Blood from 26 ischemic stroke patients (18 CE and 8 LAA) was collected into EDTA tubes within the first 4.5h after the onset of neurological symptoms. After centrifugation, buffy coat was mixed with RNAlater solution and preserved at -80°C until RNA isolation. In order to obtain a common signature and to avoid interindividual variability, equal amounts of RNA from individual samples were pooled based on their stroke etiology and according to clinical characteristics: 18 CE strokes were divided among 7 different pools and 8 LAA strokes among 4 pools.
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| Contributor(s) |
García-Berrocoso T, Montaner J, Fernández-Cadenas I |
| Citation(s) |
31475302 |
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| Submission date |
Dec 18, 2018 |
| Last update date |
Jan 07, 2020 |
| Contact name |
Elena Palà |
| E-mail(s) |
[email protected]
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| Organization name |
Institut de Recerca Hospital Vall d’Hebron
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| Lab |
Neurovascular Research Laboratory
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| Street address |
Pg Vall d’Hebron 119-129
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| City |
Barcelona |
| ZIP/Postal code |
08035 |
| Country |
Spain |
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| Platforms (1) |
| GPL5175 |
[HuEx-1_0-st] Affymetrix Human Exon 1.0 ST Array [transcript (gene) version] |
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| Samples (11)
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| Relations |
| BioProject |
PRJNA510578 |
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