|
| Status |
Public on Oct 30, 2020 |
| Title |
Genomic and Epigenomic EBF1 Alterations Modulate TERT Expression in Gastric Cancer [ChIP-Seq - EBF1, EZH2] |
| Organism |
Homo sapiens |
| Experiment type |
Genome binding/occupancy profiling by high throughput sequencing
|
| Summary |
Multiple convergent pathways resulting in inhibition of the transcription factor EBF1 is a major cause of TERT upregulation.
|
| |
|
| Overall design |
NanoChIP-seq, Capture-C, CapStarr-Seq and TF-ChIPSeq were integrated to study the regulation mechanisms of EBF1 and TERT expression in gastric cancer.
|
| |
|
| Contributor(s) |
Xing M, Ooi W, Tan P |
| Citation(s) |
34635154 |
| |
| Submission date |
Oct 18, 2018 |
| Last update date |
Nov 03, 2021 |
| Contact name |
Wen Fong Ooi |
| E-mail(s) |
[email protected]
|
| Organization name |
Genome Institute of Singapore
|
| Street address |
60 Biopolis
|
| City |
Singapore |
| ZIP/Postal code |
470110 |
| Country |
Singapore |
| |
|
| Platforms (2) |
| GPL11154 |
Illumina HiSeq 2000 (Homo sapiens) |
| GPL21290 |
Illumina HiSeq 3000 (Homo sapiens) |
|
| Samples (6)
|
|
| This SubSeries is part of SuperSeries: |
| GSE121140 |
Genomic and Epigenomic EBF1 Alterations Modulate TERT Expression in Gastric Cancer |
|
| Relations |
| BioProject |
PRJNA497465 |
| SRA |
SRP166124 |
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